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12 542 (0,113s)

Project

Novel Tools for Cell Cycle Analysis (TA03010719)

The determination of the cell proliferation activity is a basic methodological approach for the evaluation of the cell population conditions in many situations e.g. in the evaluation of the genotoxicity or in the a...

EI - Biotechnologie a bionika

  • 2013 - 2015
  • 9 600 tis. Kč
  • 6 000 tis. Kč
  • TA ČR
Project

Molecular mechanism of proliferation of leukemic monoblasts activated by v-Myb oncoprotein (IAA5052309)

oncoprotein activates mitogenic pathways of myeloid cells and thus makes them to proliferate autonomously. The v-myb region resposible for this activity has been precisely proliferation of transformed leu...

EB - Genetika a molekulární biologie

  • 2003 - 2005
  • 3 474 tis. Kč
  • 1 852 tis. Kč
  • AV ČR
Project

The role of glial cells during ischemia/reperfusion and in the course of nervous tissue regeneration. (GA305/06/1316)

/apoptosis or proliferation of the cells, and to the proliferation, migration and differentiation of endogenous neural stem cells. Using immunohistochemical activation,reactive gliosis, apoptosis, and the ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2008
  • 3 148 tis. Kč
  • 3 148 tis. Kč
  • GA ČR
Project

Influence of inositol hexaphosphate, inositol and sodium selenite on proliferation and apoptosis colorectal carcinoma cells (GP301/06/P047)

substances on cells will be determined from the point of view ofcell proliferation (metabolic activity assay - WST, bromodeoxyuridine incorporation assay - BrdU), cell in treatment of colorectal malignant cell...

FD - Onkologie a hematologie

  • 2006 - 2008
  • 764 tis. Kč
  • 764 tis. Kč
  • GA ČR
Project

Principal signaling pathways regulating NG2 glia proliferation and differentiation following brain injuries (GA17-04034S)

an important role in proliferation and cell-fate decision of NG2-glia. The main objective of this study is to define the role of the Shh and Wnt pathways in NG2-glia proliferationIn the adult brain NG2-glia represent an im...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2019
  • 12 507 tis. Kč
  • 11 937 tis. Kč
  • GA ČR
Project

Transcription factor MITF ? critical regulator of proliferation and viability of melanoma cells and a target of molecular anticancer therapy. (NT11229)

the viability and proliferation of melanoma cells. The aim of this project is to identify a suitable molecular approach to fully inhibit expression and/or activity of MITF) is a key regulator of the development of embryoni...

FD - Onkologie a hematologie

  • 2010 - 2012
  • 4 638 tis. Kč
  • 4 638 tis. Kč
  • MZ
Project

Role of truncated PPM1D in genome instability and cancer development (GA20-11931S)

its impact on proliferation of the hematopoietic stem cells and its roleGenome instability is one of the hallmarks of cancer. Healthy cells protect their genome integrity by activating DNA damage response pathway ...

Oncology

  • 2020 - 2022
  • 8 339 tis. Kč
  • 8 150 tis. Kč
  • GA ČR
Project

Aligned Conductive Nanofibers for Tissue Engineering (GJ16-02316Y)

of these conductive scaffolds towards biomolecules enhancing cell adhesion, proliferation, activity or possessing other desired features will be studied. Such system will provide scaffolds will be tested for cell ...

CC - Organická chemie

  • 2016 - 2018
  • 3 508 tis. Kč
  • 3 508 tis. Kč
  • GA ČR
Project

Analysis of PTEN gene interactions in prostate cancer cell lines (NC6779)

activity and DNA sequence similarity to some cytoskeleletal proteins. The aim of our study is: 1) the verification of PTEN impact on the inhibition of proliferation in the prostate cancer cell lines LNCaP, DU-145, PC-3 2) ...

EB - Genetika a molekulární biologie

  • 2001 - 2003
  • 904 tis. Kč
  • 875 tis. Kč
  • MZ
Project

Interactions of genotoxic and non-genotoxic effects of polycyclic aromatic hydrocarbons in regulation of cell proliferation (KJB6004407)

after exposure to a set of PAHs, selected on basis of effects on cell proliferation. The proposed project aims to test the hypothesis that ultimate fate of cells affected by PAH exposure might be determined both by accumul...

ED - Fyziologie

  • 2004 - 2006
  • 1 550 tis. Kč
  • 1 550 tis. Kč
  • AV ČR
  • 1 - 10 out of 12 542