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5 880 (0,175s)

Project

The relationship between cell size and the size of cellular organelles during early embryonic development in mammals (GA19-24528S)

conditions are characterized by changes in cell sizes. A maintenance of cell volume cells are actually measuring their volume. Preliminary hypotheses suppose adjustment of cell volume to...

Technologies involving the manipulation of cells, tissues, organs or the whole organism (assisted reproduction)

  • 2019 - 2022
  • 7 954 tis. Kč
  • 7 588 tis. Kč
  • GA ČR
Project

Role of the aquaporin channel AQP4 in the development of cytotoxic brain edema following brain ischemia/reperfusion (GA15-02760S)

the molecular-level mechanisms responsible for cell swelling. The main objective of the project is to elucidate the detailed mechanisms of cell swelling/volume regulation with focus on AQP4 and TRPV4 channels and their mut...

FH - Neurologie, neurochirurgie, neurovědy

  • 2015 - 2018
  • 9 426 tis. Kč
  • 9 426 tis. Kč
  • GA ČR
Project

Cell volume regulation in glial cells during brain ischemia/reperfusion (GAP303/10/1338)

in vivo. The effect of specific ion channel or transporter inhibitors on cell volume cells to regulate their volume, changes in cell membrane properties during ischemia participating in astrocyte and NG2 ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010 - 2012
  • 3 996 tis. Kč
  • 3 996 tis. Kč
  • GA ČR
Project

Highly precise temperature mapping and heat balance monitoring of living cells (GA17-20716S)

temperature and monitor energy balance in living cells. This microcalorimetric (C) system will have minimal volume surrounded with vacuum. Living cells will be inside the C in conventional cell culturing media a...

BO - Biofyzika

  • 2017 - 2021
  • 8 405 tis. Kč
  • 7 562 tis. Kč
  • GA ČR
Project

Diffusion parameters in the brain and spinal cord during injury (GA309/99/0657)

Changes in extracellular space (ECS) ionic composition, volume and geometry by cell death and astrogliosis. We shall study how injury-related glial swelling, cell-glia communication. Cellular swelling is compensated for by ...

FH - Neurologie, neurochirurgie, neurovědy

  • 1999 - 2001
  • 3 521 tis. Kč
  • 2 953 tis. Kč
  • GA ČR
Project

High precision quantification of rodent and human pancreatic islets for transplantation (NU22-01-00141)

of functional beta-cells in the graft. The current methods for islet graft assessment volume estimation assumes spherical islet shape, grossly overestimating the volumes of individual islets, and leading to exaggerated exp...

Transplantation

  • 2022 - 2025
  • 11 544 tis. Kč
  • 11 544 tis. Kč
  • MZ
Project

Relationships of ploidy level, genome and cell size in model polyploid fish with cytological and physiological impacts on conservation and culture. (GA523/08/0824)

Genome size in fishes is positively correlated to cell and nuclear size and volume. Increases in genome size due to shifts in ploidy level influence these cytological correlates causatively, with this effect persisting on both ancie...

EB - Genetika a molekulární biologie

  • 2008 - 2012
  • 7 245 tis. Kč
  • 7 245 tis. Kč
  • GA ČR
Project

KERI a.s. - robotization of production (FX03030008)

The main goal of the project is to increase the automation and robotization of production processes in the company KERI a.s. The subject of the project is the development, production and implementation of a self-service robotic cell in the <...

Mechanical engineering

  • 2021 - 2022
  • 10 095 tis. Kč
  • 5 047 tis. Kč
  • MPO
Project

Metabolomic analysis of single cells by mass spectrometry (KJB400310903)

system for small volume sample analysis of biological materials with the capability for a single cell analysis. For this work we have selected one the industrially important for the single cell analysis. Preliminary experi...

CB - Analytická chemie, separace

  • 2009 - 2009
  • 584 tis. Kč
  • 584 tis. Kč
  • AV ČR
Project

Electrophysiological and morfhological properties of glial cells after brain injury and transplantation (GA305/99/0655)

and morphology of glial cells under normal conditions. Since glial cell swelling is anaccompanying phenomenon of many pathological states, regulation of glial cell volume channels and neurotransmitter receptors of...

EA - Morfologické obory a cytologie

  • 1999 - 2001
  • 3 158 tis. Kč
  • 2 590 tis. Kč
  • GA ČR
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