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2 095 (0,224s) •

Project

Functional Organisation of the Cell (LC545)

with membranes and establishing cellular polarity. Determination of transport mechanism of integral proteins towards the cell membrane. To clarify how cytoskeletal interactions and stress. Description of protein topology i...

EA - Morfologické obory a cytologie

  • 2005 - 2011
    • •
  • 131 084 tis. Kč
    • •
  • 96 589 tis. Kč
    • •
  • MŠMT
Project

Role of membrane potential in the lateral microdomain organization of the plasma membrane (GAP205/12/0720)

Depending on their actual chemical composition, membranes are subdivided. Rearrangement of the microdomains strongly modulates biochemical processes on the membrane and cellular responses. The main goal of the project is to...

BO - Biofyzika

  • 2012 - 2014
    • •
  • 6 230 tis. Kč
    • •
  • 6 230 tis. Kč
    • •
  • GA ČR
Project

Self-organization principles of non-membrane-bound organels in eukaryotic cells (GA204/07/0133)

indifferent cellular organelles and, based on these data, model formation and maintenance of these structures. We aim to apply self-organization models on three cellular non-membrane bound compartments: the nucleolus, the ...

EA - Morfologické obory a cytologie

  • 2007 - 2011
    • •
  • 8 107 tis. Kč
    • •
  • 8 107 tis. Kč
    • •
  • GA ČR
Project

Molecular mechanisms of membrane interaction and translocation of adenylate cyclase toxin from Bordetella pertussis (GA15-09157S)

to a pore-forming cytolysin, which inserts into cellular membranes and mediates translocation of the AC domain directly across the membrane into cell cytosol, where it catalyzes conversion of ATP to cAMP, a key molecule su...

CE - Biochemie

  • 2015 - 2017
    • •
  • 5 994 tis. Kč
    • •
  • 5 994 tis. Kč
    • •
  • GA ČR
Project

Peptides controlling membrane curvature (LUC25012)

The project focuses on lipid membrane curvature and peptides that are sensitive to curvature or capable of modulating curvature. Membrane curvature plays a crucial role in many physiological cellular processes, such as endo...

Biophysics

  • 2025 - 2027
    • •
  • 4 689 tis. Kč
    • •
  • 4 689 tis. Kč
    • •
  • MŠMT
Project

Application of fluorescence methods to estimate the role of potassium transporters in the regulation of membrane potential and intracellular pH of yeast cells (KJB500110701)

content, tolerance to osmolytes (and thus regulation of cellular volume), pH, membrane spectroscopy of cellular pH and membrane potential, using the diS-C3(3) fluorescence probe about the transporters role in the ...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 1 349 tis. Kč
    • •
  • 1 349 tis. Kč
    • •
  • AV ČR
Project

Function of specific membrane microdomains in lipid homeostasis (GA19-04052S)

Cellular lipidome is a subject of continuous, multilayer adaptation reacting membranes. Our unpublished data indicate functional interconnection of various types of remote microdomains within the cellular architecture. For ...

Cell biology

  • 2019 - 2022
    • •
  • 5 993 tis. Kč
    • •
  • 5 993 tis. Kč
    • •
  • GA ČR
Project

Role of retroviral matrix protein in virus particle targeting and interaction with plasma membrane. (GAP302/12/1895)

with the cytoplasmic membrane. We aim to study the retroviral matrix protein (MA), a key determinant for the interaction of viral proteins with cellular transport machinery and the plasma membrane. We propose to use NMR sp...

EE - Mikrobiologie, virologie

  • 2012 - 2016
    • •
  • 8 835 tis. Kč
    • •
  • 8 835 tis. Kč
    • •
  • GA ČR
Project

Investigation of the mechanism of membrane translocation of the adenylate cyclase toxin (IAA5020907)

of spontaneous protein translocation directly across the cellular membrane. Elucidation-membrane interactions and is the principal aim of this proposal. Here, dynamics of membrane interaction, membrane to...

CE - Biochemie

  • 1999 - 2003
    • •
  • 7 321 tis. Kč
    • •
  • 4 975 tis. Kč
    • •
  • AV ČR
Project

Protein Affinity and Selectivity to Cellular Membranes (GA20-20152S)

at membranes of specific organelles to perform specialized functions. However, the relationship between the protein sequence and its membrane preference is not yet known for membranes with specific composition and curvatur...

Physical chemistry

  • 2020 - 2022
    • •
  • 8 105 tis. Kč
    • •
  • 8 105 tis. Kč
    • •
  • GA ČR
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