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1 309 (0,111s)

Project

Time resolved microfluorimetry in application to cellular monitoring of potential chemoterapetics (7AMB14FR020)

- Test of the applicability of the time-resolved microspectrofluorimetry in order to distinguish various porphyrin binding modes in complexes with oligonucleotides and aptamers. - Spectroscopic study of the complex formation between novel cationic po...

BO - Biofyzika

  • 2014 - 2015
  • 108 tis. Kč
  • 108 tis. Kč
  • MŠMT
Project

Environmental impact of noble metal nanoparticles (GA17-10907S)

on plants will be studied on both cellular and whole plant levels and will cover especially an uptake of various NPs differing in their composition, size and shape......

JJ - Ostatní materiály

  • 2017 - 2021
  • 10 306 tis. Kč
  • 9 016 tis. Kč
  • GA ČR
Project

Peptide Drug Delivery Systems Targeting Macrophages for Antimycobacterial Active Compounds (GJ17-27514Y)

will be investigated additionally for their cellular uptake and intracellular activity in M...

FR - Farmakologie a lékárnická chemie

  • 2017 - 2019
  • 4 525 tis. Kč
  • 4 525 tis. Kč
  • GA ČR
Project

Design and investigation of novel antimicrobial agents active against drug-resistant and biofilm-forming gram-positive bacteria (GJ20-19638Y)

and cellular uptake will be also investigated. The most promising candidates...

Pharmacology and pharmacy

  • 2020 - 2022
  • 6 712 tis. Kč
  • 6 699 tis. Kč
  • GA ČR
Project

A robust reactive-oxygen-species scavenging nanomedicine for antioxidant therapy (GA25-15996S)

nanocarriers in vitro regarding their cytotoxicity, cellular uptake, stimuli-responsive...

Health-related biotechnology

  • 2025 - 2027
  • 12 933 tis. Kč
  • 12 864 tis. Kč
  • GA ČR
Project

Development of USB - International mobility - MSCA IV - F (EH22_010/0012646)

The project will use Gd ions of PS and PVC nanoplastics to systematically study ecotoxicity, interactions and particle deposition in freshwater and marine microalgae. The aim is to assess toxicity at the cellular and population level, analyz...

Other natural sciences

  • 2025 - 2028
  • 18 162 tis. Kč
  • 4 594 tis. Kč
  • MŠMT
Project

Mechanical regulation of functionalized DNA nanostructures processing by hepatic cells (LUAUS24038)

. Growing number of research indicate that the cellular physiological microenvironment uptake and processing of DNs is basically lacking. Thus, we aim to gain deep knowledge about molecular biophysical mechanisms of modulation of DN...

Biophysics

  • 2024 - 2028
  • 12 803 tis. Kč
  • 12 803 tis. Kč
  • MŠMT
Project

Metabolomics and proteostasis in cancer stem cells (GA21-13188S)

It is now known that cancer cells are phenotypically heterogeneous within a given tumor and contain cellular subpopulations with stem cell-like properties) and of energy production (glucose uptake and mitochondrial activity) represe...

Biochemistry and molecular biology

  • 2021 - 2023
  • 8 098 tis. Kč
  • 7 962 tis. Kč
  • GA ČR
Project

Development of novel compounds as tools to address unfavourable epidemiology of resistant fungal infections (NW24-05-00539)

and combinations on mycotic biofilm communities will also be evaluated. Cellular uptake...

Pharmacology and pharmacy

  • 2024 - 2027
  • 14 090 tis. Kč
  • 14 090 tis. Kč
  • MZ
Project

Iron-chelating polymer microparticles (GA19-01438S)

that limits iron entry into the blood. Limiting iron uptake would thus be a way to treat hemochromatosis. The mechanism of iron uptake is however complex due to coexistence of three forms of iron in diet [Fe(II), Fe(III) and heme-c...

Hematology

  • 2019 - 2021
  • 8 901 tis. Kč
  • 8 754 tis. Kč
  • GA ČR
  • 1 - 10 out of 1 309