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29 (0,16s) •

Project

Impact of repetitive sequences on structure, evolution and function of plant centromeres (GAP501/11/1843)

Centromere is one of the most important chromosome domains as it is essential of centromere is conserved in all eukaryotes, underlying DNA is surprisingly variable between species and its role in centromere determination an...

EB - Genetika a molekulární biologie

  • 2011 - 2015
    • •
  • 7 210 tis. Kč
    • •
  • 7 210 tis. Kč
    • •
  • GA ČR
Project

A pangenomic view of expanding centromere (GA24-10036S)

Centromeres are essential chromosomal regions that facilitate proper, centromeres exhibit high variation in size, structure, and sequence composition. However, compromising our understanding of the general principles of centrome...

Genetics and heredity (medical genetics to be 3)

  • 2024 - 2026
    • •
  • 10 483 tis. Kč
    • •
  • 10 483 tis. Kč
    • •
  • GA ČR
Project

Utilizing new models and technologies to elucidate centromere determination in plants (GA17-09750S)

Centromeres are chromosomal structures which are essential for the proper for hereditary processes, the principles of centromere determination are only poorly understood. This is mainly due to the lack of knowledge about centrom...

EB - Genetika a molekulární biologie

  • 2017 - 2021
    • •
  • 6 501 tis. Kč
    • •
  • 6 207 tis. Kč
    • •
  • GA ČR
Project

Evolutionary new centromeres in plants (GA23-06840S)

Centromeres are required for regular segregation of monocentric chromosomes. Centromere repositioning (CR) and evolutionary new centromeres (ENCs) refer to the formation of a centromere at a different position on t...

Plant sciences, botany

  • 2023 - 2025
    • •
  • 12 446 tis. Kč
    • •
  • 12 446 tis. Kč
    • •
  • GA ČR
Project

REGULATION OF CHROMOSOME SEGREGATION DURING MEIOSIS (IAA501620801)

first meiosis whereas centromeric cohesin is removed during second meiosis. However, separase is active in both divisions, therefore the centromeric cohesin must to the protection of centromeric cohesion in yeast meiosis. ...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 3 528 tis. Kč
    • •
  • 3 528 tis. Kč
    • •
  • AV ČR
Project

Evolutionary conserved structural features of centromeric and telomeric DNA (GA13-28310S)

NMR and CD spectroscopy will be used to characterize conformational plasticity of centromeric and telomeric DNA from Saccharomyces cerevisiae, Arabidoptis thaliana of non-canonical (non-B) DNA motifs in centromeric and telomeric DNA...

BO - Biofyzika

  • 2013 - 2016
    • •
  • 6 882 tis. Kč
    • •
  • 6 882 tis. Kč
    • •
  • GA ČR
Project

Evolution of genome size - a new role for the centromere drive (GA20-15989S)

Maintaining the size ratio of chromosomes (“luggage”) and their kinetochores (“handles”) should mean that the kinetochore size divergence caused by centromere drive the drive is absent. This so far unrecognized effect of centromere ...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2020 - 2023
    • •
  • 8 866 tis. Kč
    • •
  • 8 866 tis. Kč
    • •
  • GA ČR
Project

Changes in kinetochore composition and structure associated with holocentric chromosome formation (GA20-25440S)

The centromere and kinetochore are essential for proper chromosome segregation, therefore, understanding the principles of their organization, structure and function is of great importance. Most research into centromeres and kinetoc...

Genetics and heredity (medical genetics to be 3)

  • 2020 - 2023
    • •
  • 8 008 tis. Kč
    • •
  • 8 008 tis. Kč
    • •
  • GA ČR
Project

Composition of plant kinetochores and its evolutionary plasticity in the context of centromere organization (GA25-15809S)

, focusing on species that differ in their mode of centromere organization. Deciphering...

Genetics and heredity (medical genetics to be 3)

  • 2025 - 2027
    • •
  • 10 332 tis. Kč
    • •
  • 10 332 tis. Kč
    • •
  • GA ČR
Project

Evolution of holocentric chromosomes (GA13-29362S)

An adaptive origin of holocentric chromosomes (without localized centromere) as a defense against centromere drive will be analyzed using selection regimes acting on kinetochore proteins. To explain surprisingly negative 2C/2n corre...

EF - Botanika

  • 2013 - 2016
    • •
  • 9 996 tis. Kč
    • •
  • 9 996 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 29