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413 (0,165s) •

Project

Diagnostic utility of hTERC and MYCC genes amplifications in initiations and development of cervical intraepithelial dysplasia and cervical carcinoma (NT11089)

1. In cervical precancerous lesion and cervical carcinoma were repeatedly diagnosed specific genetic abnormalities (hTERC and MYCC genes amplifications), which can be considered as important genetic markers predicting malig...

EB - Genetika a molekulární biologie

  • 2010 - 2013
    • •
  • 4 975 tis. Kč
    • •
  • 4 975 tis. Kč
    • •
  • MZ
Project

Genetic prediction of late toxicity of radiotherapy for cervical cancer (NT11334)

The aim of the project is to analyse a predictive influence of ATM gene mutation and TGFß protein polymorphism upon the risk of late treatment complications in patients with locally advanced cervical carcinoma treated with radical c...

FD - Onkologie a hematologie

  • 2010 - 2013
    • •
  • 7 448 tis. Kč
    • •
  • 7 448 tis. Kč
    • •
  • MZ
Project

A Study on HPV- Induced Pathogenesis of Cervical Neoplasias. (IZ4070)

The elucidation of the qualitative and quantitative aspects of the interaction between papilomaviruses and infected organism,determination of the relation of HPV to the development of cervical carcinoma with reference to other ris f...

FD - Onkologie a hematologie

  • 1997 - 1999
    • •
  • 41 000 tis. Kč
    • •
  • 4 865 tis. Kč
    • •
  • MZ
Project

Plant production of human papillomavirus proteins and immunogenic properties of transgenic plant tissues (GA521/05/2092)

The aim of the project is the regeneration of transformed plants of tomato, potato, carrot and lettuce that produce large amounts of human papillomavirus 16 proteins LI and E7. The major etiological role of particular types of human papillomaviruses ...

EI - Biotechnologie a bionika

  • 2005 - 2007
    • •
  • 4 356 tis. Kč
    • •
  • 4 356 tis. Kč
    • •
  • GA ČR
Project

Significance of preoperation risk factors, perioperational evaluation and ultramicrostanding of sentinel lymph-nodes in the early stages of uterine cervical and vulvar cancer. (NR8434)

of the micrometastasis and metastasis in early stages of uterine cervical carcinoma and vulval carcinoma. Elaboration of the optimal treatment management in the womenin accordance......

FK - Gynekologie a porodnictví

  • 2005 - 2007
    • •
  • 3 211 tis. Kč
    • •
  • 3 070 tis. Kč
    • •
  • MZ
Project

Gene Therapy of Cancer - Optimization of Therapeutic Protocols (NC45012)

therapy of a carcinoma etiologically identical to human cervical carcinThe project is aimed at the optimization of therapeutic protocols for gene therapy of tumours in preclinical models of three basic types of neoplasms-carcin...

FD - Onkologie a hematologie

  • 1998 - 2000
    • •
  • 595 tis. Kč
    • •
  • 595 tis. Kč
    • •
  • MZ
Project

Gene Therapy of Cancer - Optimization of Therapeutic Protocols (NC45011)

. for gene therapy of a carcinoma etiologically identical to human cervical carcinThe project is aimed at the optimization of therapeutic protocols for gene therapy of tumours in preclinical models of three basic types of neoplasms-...

FD - Onkologie a hematologie

  • 1998 - 2000
    • •
  • 6 055 tis. Kč
    • •
  • 5 365 tis. Kč
    • •
  • MZ
Project

Combined therapy of metastazising tumours induced by HPV 16 E8/E7 and ras oncogenes (GA301/01/0985)

The proposed project is aimed at the therapy of murine tumours induced by the aetiological agent of human cervical carcinoma, HPV16, resp. by the E6/E7 oncogenes of this virus. Another aim is to study the effect of therapy of the su...

FD - Onkologie a hematologie

  • 2001 - 2003
    • •
  • 5 402 tis. Kč
    • •
  • 4 545 tis. Kč
    • •
  • GA ČR
Project

Detection of subclinical metastasis in lymphatic nodes in early stages cervical cancers using detection of human papillomavirus DNA (NS10037)

The evidence of micro-metastases in catchment pelvic lymphatic nodes is a prognostic parameter in early- stage cervical carcinoma recently discussed in the literature. The assessment of the presence of infection by human papillomavi...

FK - Gynekologie a porodnictví

  • 2008 - 2010
    • •
  • 3 180 tis. Kč
    • •
  • 3 180 tis. Kč
    • •
  • MZ
Project

A promotor methylation of TSGs associated with HPV-driven carcinogenesis as a screening tool for anal carcinoma at risk population - validation study (NV17-31777A)

and biological behavior very similar to cervical cancer, therefore the investigative of cervical cancer. This research should therefore validate DNA methylation as a potential......

EB - Genetika a molekulární biologie

  • 2017 - 2021
    • •
  • 8 456 tis. Kč
    • •
  • 8 152 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 413