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Project

Aspects of proteomics of chalcone synthases and chalcone synthase-like proteins in hop important for lupulin biosynthesis (GP521/06/P323)

the enzyme activities of chalcone synthases and chalcone synthase-like proteins, which members of hop chalcone synthase gene family, which were detected in hop genome......

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 1 200 tis. Kč
    • •
  • 1 200 tis. Kč
    • •
  • GA ČR
Project

Antisense and sense RNA targeting of chalcone synthase - related sequences study of genes involved in bitter acid biosynthesis in hop (H. lupulus) (GA521/99/1591)

Characteristics of the project (an abstract of max. 15 lines): Chalcone synthase (CHS)-like enzyme(s) is considered to play a key role in initial step of biosynthesis of bitter acids in hop (Zuurbier et al.:Phytochemistry,38:77,1995...

EB - Genetika a molekulární biologie

  • 1999 - 2001
    • •
  • 6 258 tis. Kč
    • •
  • 4 474 tis. Kč
    • •
  • GA ČR
Project

Phenolic metabolism, antioxidants and stress tolerance in algae (GA14-28933S)

and activities of related proteins (phenylalanine/tyrosine ammonia-lyase and chalcon synthase...

ED - Fyziologie

  • 2014 - 2018
    • •
  • 3 120 tis. Kč
    • •
  • 3 120 tis. Kč
    • •
  • GA ČR
Project

Functional genomics of hop (H. lupulus L.) with respect to genes co-determining lupulin production (GA521/03/0072)

It is proposed to analyse structural and functional aspects of genomic organization of chalcone synthase (chs) homologues, which have been found recently to be involved in biosynthesis of bitter acids valuable for bitterness of beer...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 5 517 tis. Kč
    • •
  • 2 944 tis. Kč
    • •
  • GA ČR
Project

Combinatorial regulation and network of transcription factors involved in the biosynthesis of medicinal prenylflavonoids in hop (Humulus lupulus L.). (GA13-03037S)

Hop is source of bitter acids and medicinal prenylchalcones, including xanthohumol. During last years we have characterized lupulin-specific chalcone synthase chs_H1 and transcription factors from Myb, bHLH and WDR families that act...

EB - Genetika a molekulární biologie

  • 2013 - 2017
    • •
  • 14 323 tis. Kč
    • •
  • 14 323 tis. Kč
    • •
  • GA ČR
Project

Callose synthases - dynamics and mechanisms of secretion. (GA18-12579S)

Callose synthases are transmembrane enzymes producing callose (β-1,3-glucan synthase paralogs, acting in different tissues and processes. So far, most for their function. In our previous project, we showed that callose synthase<...

Plant sciences, botany

  • 2018 - 2023
    • •
  • 4 949 tis. Kč
    • •
  • 4 949 tis. Kč
    • •
  • GA ČR
Project

DAPIT protein and its role in biogenesis of mitochondrial ATP synthase (GA16-01813S)

FoF1-ATP synthase composed of 15 core structural subunits is the key enzyme of this novel protein for biogenesis of ATP synthase, its structural properties, lipid synthase energetics, we will also test possible involvement ...

EB - Genetika a molekulární biologie

  • 2016 - 2020
    • •
  • 6 121 tis. Kč
    • •
  • 5 839 tis. Kč
    • •
  • GA ČR
Project

Computational and Experimental Characterization of Enzymes for Sustainable Design of Bioplastics (GM25-17459M)

depolymerases exists, its counterpart summarizing knowledge of PHA synthases is missing a novel classification of PHA synthases. Moreover, we will experimentally characterize in vitro and in vivo experiments to describe the propert...

Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

  • 2025 - 2029
    • •
  • 24 955 tis. Kč
    • •
  • 24 955 tis. Kč
    • •
  • GA ČR
Project

Mechanism of ATP synthase biogenesis and the role of TMEM70 protein (GAP303/11/0970)

ATP synthase is the key enzyme of mitochondrial energy provision, responsible that are assembled into a functional ATP synthase in a stepwise process that depends on several helper proteins. Recently we have discovered a new type of...

CE - Biochemie

  • 2011 - 2015
    • •
  • 8 963 tis. Kč
    • •
  • 8 963 tis. Kč
    • •
  • GA ČR
Project

Supramolecular organization of mitochondrial ATP synthase in metabolic regulations (GA17-08565S)

Oligomers of mitochondrial ATP-synthase form cristae edges and determine cristae morphology in relation to metabolism. This relationship will be elucidated antibodies against ATP-synthase subunits; or by homo-FRET (energy transfer b...

EA - Morfologické obory a cytologie

  • 2017 - 2019
    • •
  • 6 594 tis. Kč
    • •
  • 6 462 tis. Kč
    • •
  • GA ČR
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