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Immunological properties of human progenitor cells and their clinical utilization (NI7540)
Detection od chemokine receptors on the human progenitor cells. ( CD34+) Study of the expression of chemokine receptors on normal and pathological cells and their importance for the detection of the main chemokine receptors...
FN - Epidemiologie, infekční nemoci a klinická imunologie
- 2003 - 2005 •
- 3 741 tis. Kč •
- 3 561 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (95%)
Poskytovatel: Ministerstvo zdravotnictví
Immunoregulatory function of cytokine and chemokine receptors in pathogenesis and pathophysiology of blood diseases (NI5884)
Study of the expression of cytokine and chemokine receptors on normal and pathological cells and their importance in the immunology, pathogenesis and pathophysiology of blood diseases. The analytic approach for the detection of the main cyto...
FN - Epidemiologie, infekční nemoci a klinická imunologie
- 2000 - 2002 •
- 3 695 tis. Kč •
- 3 335 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2000 - 1. 1. 2002
Uznané náklady
Podpora ze státního rozpočtu (90%)
Poskytovatel: Ministerstvo zdravotnictví
The role of selected chemokine receptors and interferone-beta in the pathogenesis of rheumatoid arthritis (NI6459)
Identification of the role for CXCR3 and CCR5 and their ligands in the synovial tissue of patients with early rheumatoid arthritis. Exploration of the role of interferon beta in the synovial inflammation and assessment of its suppresive effect in vit...
FN - Epidemiologie, infekční nemoci a klinická imunologie
- 2001 - 2003 •
- 3 146 tis. Kč •
- 3 120 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2001 - 1. 1. 2003
Uznané náklady
Podpora ze státního rozpočtu (99%)
Poskytovatel: Ministerstvo zdravotnictví
Expression-profiling of chemokine ligands and receptors in pulmonary sarcoidosis (GA310/05/2614)
patients, mRNA expression of genes, relevant for chemokine-driven migration processes will be investigated in bronchoalveolar fluid in a proteomic study. Besides chemokine ligand......
EC - Imunologie
- 2005 - 2007 •
- 3 297 tis. Kč •
- 3 297 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Mechanism of tissue inflammation in patients with polymyositis and dermatomyositis (NI5369)
Mechanisms of immune changes and muscle damage in patients with polymyositis and dermatomyositis. Comparison of immunohistology from affected and non - affected muscles detected by magnetic resonance. CC chemokine and chemokine rece...
FE - Ostatní obory vnitřního lékařství
- 1999 - 2001 •
- 2 624 tis. Kč •
- 2 624 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1999 - 1. 1. 2001
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Molecular and cellular mechanisms in ethiopathogenesis of nasal polyposis (NS10054)
Signaling pathways and changes in expression of intracellular signaling molecules in nasal polyps. Expression of Toll-like receptors as potential markers for identifying etiological environmental factors in nasal polyps. Changes in expression of ...
FF - ORL, oftalmologie, stomatologie
- 2008 - 2011 •
- 2 140 tis. Kč •
- 2 140 tis. Kč •
- MZ
Řešení projektu: 1. 7. 2008 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
PAR´s, chemokines and their receptors´ expression changes in pulmonary fibrosing processes and in pulmonary processes with alveolar number reduction without scaring (IPF vs. COPD) (NS10423)
We assume differences between expression of cytokines, chemokines and their receptors in patients diseased by IPF and COPD. It could be expected that the level of PAR´s expression will be significantly higher in chronic inflamatory process (...
FC - Pneumologie
- 2009 - 2011 •
- 4 179 tis. Kč •
- 4 179 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2009 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
The role of adhesion molecules and cytokines in hematopoirtic stem cell mobilization in healthy donors (NR9268)
1. Analysis of differences in secretion of chemokines playing role in CD34+ mobilization mechanism before and during granulocyte- colony stimulating factor administration using ELISA methods and multiplex analysis. Flow cytometric analysis i...
FD - Onkologie a hematologie
- 2007 - 2009 •
- 1 981 tis. Kč •
- 1 981 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2007 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Analysis of the role of transmembrane adaptor protein OPAL1 in the regulation of leukocyte receptor signaling with focus on chemokine receptor CXCR4 (GA16-07425S)
Chemokine receptor CXCR4 governs retention and homing of hematopoietic stem and progenitor cells and other leukocytes to the bone marrow. It is also involved in tumor metastasis and HIV infection and it is targeted in a number of disease the...
EC - Imunologie
- 2016 - 2020 •
- 7 917 tis. Kč •
- 7 134 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 22. 7. 2020
Uznané náklady
Podpora ze státního rozpočtu (90%)
Poskytovatel: Grantová agentura České republiky
Study of mediators of fibrotic processes in patients with diffuse lung diseases and their clinical application (NT11117)
1.The project will investigate mRNA & protein expression profile (EP) of selected molecules, related to pro-fibrotic processes in diffuse lung diseases (DLDs). 2. The EP of chemokines, cytokines and other regulatory molecules contributing to...
EC - Imunologie
- 2010 - 2015 •
- 9 746 tis. Kč •
- 9 746 tis. Kč •
- MZ
Řešení projektu: 1. 9. 2010 - 31. 12. 2015
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
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