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19 (0,111s) •

Project

Changes in Chemoresistance/Chemosensitivity of Ovarian Cancer Cells (NS9737)

1)The changes in chemoresistance/chemosensitivity of ovarian cancer cells by means of MTT -WST-1 test and assessment of resistance proteins (MRP, LRP, p170) in a course of treatment. 2) Samples of ascitic fluid or solid tissue will be taken ...

FK - Gynekologie a porodnictví

  • 2008 - 2010
    • •
  • 2 537 tis. Kč
    • •
  • 2 537 tis. Kč
    • •
  • MZ
Project

The use of cultured breast cancer cells for the development of the individualized chemosensitivity/chemoresistance assay in vitro. (NC5614)

The use of cultured breast carcinoma cells for development of predictive chemosensitivity/resistance testing for all currently available chemotherapeutic modalities aimed at finding the best chemotherapy for individual pacients.......

FD - Onkologie a hematologie

  • 1999 - 2001
    • •
  • 2 572 tis. Kč
    • •
  • 2 572 tis. Kč
    • •
  • MZ
Project

Assesment of ventilatory chemosensitivity in men - new method. (IZ1173)

9F - 9

  • 1992 - 1994
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • MZ
Project

Neoadjuvant treatment for oesophageal cancer and its role on short and long-term results after oesophageal resection (ND7169)

The aim of the project is to assess neoadjuvant therapy in the management of oesophageal cancer. This therapy will be given according to chemosensitivity of cancer cells to cytotoxic drugs that could be assessed with the MTT test. An outcome...

FJ - Chirurgie včetně transplantologie

  • 2002 - 2004
    • •
  • 1 256 tis. Kč
    • •
  • 1 226 tis. Kč
    • •
  • MZ
Project

Biology of chemosensitization of ovary and breast tumour cells tested for chemosensitivity/resistance in vitro and consequences for therapeutic indication. (NR8145)

Untargeted chemotherapy of tumours is usually unsuccessful in 30% in the first line. Tests of chemoresistance in vitro should exclude cytostatics to which the cells are resistant. The MTT test will respond to the question only in the yes/no manner. T...

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 2 045 tis. Kč
    • •
  • 1 565 tis. Kč
    • •
  • MZ
Project

The analysis of unique rare entities of pancreatic ductal adenocarcinoma (NV19-03-00097)

prognosis (i/ chemosensitive patients with DNA-repair mutations, and ii/ long surviving...

Oncology

  • 2019 - 2022
    • •
  • 11 506 tis. Kč
    • •
  • 11 258 tis. Kč
    • •
  • MZ
Project

Biodegradable hydrogels for long-term release of cytostatics and their use in combined anticancer therapy (IAB5020201)

days) release of anticancer drugs in combination with chemosensitizers...

FD - Onkologie a hematologie

  • 2002 - 2004
    • •
  • 872 tis. Kč
    • •
  • 504 tis. Kč
    • •
  • AV ČR
Project

Multidrug Resistance in Cancer Molecular, Celular and Clinical Aspects. (IZ4132)

of chemosensitizers into clinical practice....

FD - Onkologie a hematologie

  • 1997 - 2001
    • •
  • 13 372 tis. Kč
    • •
  • 13 079 tis. Kč
    • •
  • MZ
Project

Predictive factors for adjuvant chemotherapy in patients with operable stage of non-small cell lung cancer (NS9959)

with prospective study. Comparison of detected chemosensitivity by MTT test with pathological...

FD - Onkologie a hematologie

  • 2008 - 2010
    • •
  • 4 029 tis. Kč
    • •
  • 3 826 tis. Kč
    • •
  • MZ
Project

Prediction of chemosensitivity / chemoresistance to the target therapy of breast carcinoma with amplification of the Her-2 gene, based on the analysis of Akt signal pathway and serial quantitative (NR8335)

The project is focused on patients with HER-2 positive breast cancer and the aim is to identify new predictive markers of response to trastuzumab. Our focus is the AKT pathway that plays important role in cancer cells chemoresistance and the value of...

FD - Onkologie a hematologie

  • 2005 - 2007
    • •
  • 3 564 tis. Kč
    • •
  • 3 495 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 19