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Treatment of deep cartilage defects in the knee by mosaicplasty combined with autologous cultivated chondrocytes in Tissucol - prospective study (ND5972)
Study evaluated longtime results following mosaicplasty in combination with autologous cultivated chondrocytes. Further we want to find the optimal place for cartilage pick-up and to improve the mechanical characteristic of chondrocyte
FI - Traumatologie a ortopedie
- 2000 - 2002 •
- 2 168 tis. Kč •
- 2 111 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2000 - 1. 1. 2002
Uznané náklady
Podpora ze státního rozpočtu (97%)
Poskytovatel: Ministerstvo zdravotnictví
Reconstruction of the Joint Surface using autologous osteochondral Grafts, autologous cultured Chondrocytes in Suspension and in bioactive Glass-Ceramic Material. An experimental and clinical Study. (ND6042)
of chondrocytes. Conductivity of bioioactive glass-ceramic materials and morphological changes of human chondrocytes cultivated in Tissue culture on used material surface. Transplantation of autologous chondrocytes. Transp...
FI - Traumatologie a ortopedie
- 2000 - 2002 •
- 1 469 tis. Kč •
- 1 279 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2000 - 1. 1. 2002
Uznané náklady
Podpora ze státního rozpočtu (87%)
Poskytovatel: Ministerstvo zdravotnictví
Treatment of deep cartilage defects in the Knee and in the ankle with autologous chondrocyte transplantation. (IZ3461)
FJ - Chirurgie včetně transplantologie
- 1996 - 1998 •
- 2 394 tis. Kč •
- 2 390 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1996 - 1. 1. 1998
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Human Stem Cells Differentiation in Chondrocytes, Cartilage Mechanical Property - Experimental Study, Part I. (NR8121)
Determination of cartilage model using stem cells extracted from human bone marrow. Determination of the cartilage tissue using cultivated human chondrocytes. Evaluatuin of the basic mechanical properties of the tissue after the human stem c...
FI - Traumatologie a ortopedie
- 2004 - 2006 •
- 3 418 tis. Kč •
- 3 235 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2004 - 1. 1. 2006
Uznané náklady
Podpora ze státního rozpočtu (95%)
Poskytovatel: Ministerstvo zdravotnictví
Treatment of deep chondral defects with autologous chondrocyte implantation on porous matrices (ND7375)
The project investigates possibilities of chondral defect treatment with autologous chondrocyt implantation on a porous matrix ( hyaluronic ac., collagen). Histologic, imunohistologic and mechanical features of the newly formed cartilage are...
FI - Traumatologie a ortopedie
- 2003 - 2005 •
- 4 539 tis. Kč •
- 4 165 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2003 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (92%)
Poskytovatel: Ministerstvo zdravotnictví
Scaffolds from liposome nanofibers for tissue engineering (IAA500390702)
Cartilages breakdown due to disease results in a severe pain and disability. A new approach has recently appeared: implantation of the autologous chondrocytes and construction of artificial cartilages based on seeding of autologous chond...
BO - Biofyzika
- 2007 - 2011 •
- 4 391 tis. Kč •
- 4 391 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2007 - 31. 12. 2011
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Akademie věd České republiky
Miniinvasive osteosynthesis and autogenous chondrocytic transplantation in the treatment of trauma to the physeal grouwth plate - a complex experimental study (ND6849)
The experimental study is thoroughly engaged with the trabsolantation of autogenous chondrocytic grafts into the area of injured growth plates as part of treating long bone fractures in the physis. It is the aim of the project to elaborate i...
FJ - Chirurgie včetně transplantologie
- 2001 - 2002 •
- 1 131 tis. Kč •
- 1 104 tis. Kč •
- MZ
Řešení projektu: 1. 1. 2001 - 1. 1. 2002
Uznané náklady
Podpora ze státního rozpočtu (98%)
Poskytovatel: Ministerstvo zdravotnictví
Identification of novel therapeutic approaches to achondroplasia via analysis of FGFR3 interaction with adapter protein Frs2 (NV15-33232A)
Activating mutations in fibroblast growth factor receptor 3 (FGFR3) account for the most prevalent form of dwarfism in humans, the achondroplasia. Excessive activation of FGFR3 causes premature chondrocyte growth arrest, abnormal extracellul...
EB - Genetika a molekulární biologie
- 2015 - 2018 •
- 9 730 tis. Kč •
- 9 730 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2015 - 31. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Caspase-1 and chondrocytes integration of osteoarthritis oriented research (LUABA22019)
chondrocytes. However, the impact of individual caspases and underlying mechanisms need of the caspase-1 inhibitory effect in chondrocytes with focus on both, healthy and OA-like chondrocytes (in mouse and human model...
Technologies involving identifying the functioning of DNA, proteins and enzymes and how they influence the onset of disease and maintenance of well-being (gene-based diagnostics and therapeutic interventions [pharmacogenomics, gene-based therapeutics])
- 2022 - 2024 •
- 1 190 tis. Kč •
- 1 190 tis. Kč •
- MŠMT
Řešení projektu: 1. 7. 2022 - 31. 12. 2024
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo školství, mládeže a tělovýchovy
The correlation between expression of matrix metalloproteinases and their tissue inhibitors the influence of olomoucin (IZ3640)
FP - Ostatní lékařské obory
- 1996 - 1998 •
- 815 tis. Kč •
- 815 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1996 - 1. 1. 1998
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
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