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257 (0,134s) •

Project

Biophysical analysis of DNA condensation. Effect of new organometallic compounds of biological significance. (GA13-08273S)

DNA condensation in vitro serves as a model system for many processes of physics, biochemistry and biology. Structures of several of metal-based agents of biological significance make it possible to predict that they can also condense DNA. To enhance...

BO - Biofyzika

  • 2013 - 2016
    • •
  • 5 414 tis. Kč
    • •
  • 5 414 tis. Kč
    • •
  • GA ČR
Project

PLATELETS - use of cryopreserved platelets for treatment of massive bleeding in combat casualties (OWUVN20170002)

, reconstitution and use of cryopreserved platelets in clinical use and in the field, based and solutions for reconstitution. This objective is based on conducting of a research study separated into two parts: 1. To discern and veri...

KA - Vojenství

  • 2017 - 2019
    • •
  • 8 833 tis. Kč
    • •
  • 8 833 tis. Kč
    • •
  • MO
Project

CMV specific immune reconstitution after allogeneic hematopoietic stem cell transplantation (NS9996)

that are at risk of progressionto CMV disease and those that reconstituted their immunity well...

FD - Onkologie a hematologie

  • 2008 - 2011
    • •
  • 9 854 tis. Kč
    • •
  • 9 854 tis. Kč
    • •
  • MZ
Project

Molecular nature of DNA replication-coupled chromatin modulation (GA304/06/1691)

dependent modulation of early replicating chromatin domains manifested in situ by antibody-detected epiC positivity. By means of native chromatin immunoprecipitation and amino acid sequence analysis we want to identify chromati...

EA - Morfologické obory a cytologie

  • 2006 - 2008
    • •
  • 4 731 tis. Kč
    • •
  • 4 731 tis. Kč
    • •
  • GA ČR
Project

Molecular structure of artificially reconstituted phycobilin-protein complex (ME 483)

Scientific target of the project is to progress in determination of structure of mutant myoglobin in its free form and in the form with bound co-factor, open tetrapyrol. Organisational target of the project is to start collaboration between Universit...

CE - Biochemie

  • 2001 - 2001
    • •
  • 50 tis. Kč
    • •
  • 50 tis. Kč
    • •
  • MŠMT
Project

Organization of human nuclear chromatin (GA204/09/0973)

In this project, we want to deepen the knowledge of interphase chromatin organization. Human aneuploid carcinoma cell line and human diploid fibroblasts will serve in replicated human chromatin and its role in the organization of re...

EA - Morfologické obory a cytologie

  • 2009 - 2011
    • •
  • 4 237 tis. Kč
    • •
  • 4 237 tis. Kč
    • •
  • GA ČR
Project

The SMC5/6 complex in nucleome organization (LTC20033)

a) Characterization of activities of the SMC5/6 complexes b) Determination of the chromatin localization and dynamics of SMC5/6 c) Identification of chromatin loops dependent on SMC5/6 activities d) Development of visual models o...

Biochemistry and molecular biology

  • 2020 - 2023
    • •
  • 7 289 tis. Kč
    • •
  • 7 289 tis. Kč
    • •
  • MŠMT
Project

Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus (ME09101)

Identification of principles of collaborative action of actin-related (Arp6) and mypson (NM1) proteins in functional organization of the cell nucleus and chromatin. The project aims to asses especially their contribution to the organization ...

EB - Genetika a molekulární biologie

  • 2009 - 2010
    • •
  • 1 336 tis. Kč
    • •
  • 1 336 tis. Kč
    • •
  • MŠMT
Project

Cooperative contribution of actin- and myosin-families to the chromatin dynamics and tranion in the cell nucleus (LH12143)

Identification of principles of collaborative action of actin-related Arp6) and myosin (NM1) proteins in functional organization of the cell nucleus and chromatin, to the dynamics of chromatin movements, and to the formation of tran...

EB - Genetika a molekulární biologie

  • 2012 - 2014
    • •
  • 3 635 tis. Kč
    • •
  • 3 635 tis. Kč
    • •
  • MŠMT
Project

High throughput analysis of chromatin structure for development of novel diagnostic and therapeutic approaches in cancer. (2B06077)

DNA in nucleus is wrapped into nucleo-protein structure known as chromatin. Any transaction on DNA requires interactions of chromatin with transcription, replication-associated transcription and chromatin-modifying factors ...

EB - Genetika a molekulární biologie

  • 2006 - 2011
    • •
  • 53 217 tis. Kč
    • •
  • 47 631 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 257