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10 580 (0,105s) •

Project

Dynamic structure and function of the cell nucleus after irradiation (1P05OC084)

changes of structure of chromatin caused by low doses of ionizating radiation, changes of nucleus topology of chromatine...

BO - Biofyzika

  • 2005 - 2007
    • •
  • 2 522 tis. Kč
    • •
  • 1 043 tis. Kč
    • •
  • MŠMT
Project

High throughput analysis of chromatin structure for development of novel diagnostic and therapeutic approaches in cancer. (2B06077)

DNA in nucleus is wrapped into nucleo-protein structure known as chromatin. Any transaction on DNA requires interactions of chromatin with transcription, replication genome high throughput analysis of chromatin

EB - Genetika a molekulární biologie

  • 2006 - 2011
    • •
  • 53 217 tis. Kč
    • •
  • 47 631 tis. Kč
    • •
  • MŠMT
Project

Chromatin dynamics during DNA repair (GAP302/10/1022)

to this knowledgeby the elucidation of the processes changing the chromatin structure in the DSB vicinity. Chromatin changes represent the fundamental response of the cell to DSB andrepair. It should be found how the c...

EA - Morfologické obory a cytologie

  • 2010 - 2014
    • •
  • 6 265 tis. Kč
    • •
  • 6 265 tis. Kč
    • •
  • GA ČR
Project

Replication and chromatin organization in human cells (GA304/05/0374)

replication results in the structural chromatin changes in the vicinity of replicatedIn this project, we want to show the high-resolution view of chromatin cells and human diploid fibroblasts. Recently, we showed that ...

EA - Morfologické obory a cytologie

  • 2005 - 2007
    • •
  • 4 362 tis. Kč
    • •
  • 4 362 tis. Kč
    • •
  • GA ČR
Project

The interplay between the LEDGF chromatin reader and protein interaction modules (GA22-03028S)

the roles of disordered regions in structural coupling between chromatin reader chromatin and targets cellular partners to these areas. It has a modular composition, where the N-terminal chromatin reader domain is...

Biochemistry and molecular biology

  • 2022 - 2024
    • •
  • 9 022 tis. Kč
    • •
  • 7 842 tis. Kč
    • •
  • GA ČR
Project

*Development of kit for testing molecular effects of anti-tumor drugs on chromatin structure (FR-TI2/509)

these molecular defects and targeting the chromatin structure represents one of the promising chromatin changes closed to key hematopoietic genes to optimize and rationalize therapy......

EB - Genetika a molekulární biologie

  • 2010 - 2014
    • •
  • 20 016 tis. Kč
    • •
  • 14 812 tis. Kč
    • •
  • MPO
Project

Epigenetic toolbox to control plant telomere maintenance (GA16-04653S)

Telomeres, nucleoprotein structures at the ends of eukaryotic chromosomes, represent important structural and functional component of the chromatin. Epigenetic properties of telomeric chromatin were analysed using ...

EB - Genetika a molekulární biologie

  • 2016 - 2018
    • •
  • 5 339 tis. Kč
    • •
  • 5 144 tis. Kč
    • •
  • GA ČR
Project

Chromosome dynamics and organization during the cell cycle in normal and pathologic conditions (LC535)

and in the characterization of chromatin structure with respect to replication, transcription and dynamic changes of 3D-structure of chromosomal territories. The high-resolution analysis of chromatin organization ...

EA - Morfologické obory a cytologie

  • 2005 - 2011
    • •
  • 81 960 tis. Kč
    • •
  • 54 481 tis. Kč
    • •
  • MŠMT
Project

Chromatin Regulation of Phaseolin Transcrption (ME10038)

of a repressive chromatin structure and the presence of a nucleosome over three phased TATA in chromatin structure over the phas promoter are orchestrated to permit tranion by a two-step process. Step 1 involves <...

EB - Genetika a molekulární biologie

  • 2010 - 2012
    • •
  • 2 280 tis. Kč
    • •
  • 2 280 tis. Kč
    • •
  • MŠMT
Project

Cytogenetic study of nuclear chromatin organization in plants (GA522/03/0354)

on mitotic chromosomes. Linear structure of chromosomes (ordered arrangement of genes, heterochromatin domains, location of prominent chromosomal structures as telomeres. Inourprevious work with we elaborated immunocytochemical det...

ED - Fyziologie

  • 2003 - 2005
    • •
  • 6 924 tis. Kč
    • •
  • 3 226 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 10 580