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539 (0,115s)

Project

Fate of aneuploid cells in developing embryo and stem cell population (GA15-04844S)

Errors during chromosome segregation might cause whole chromosome aneuploidy, while DNA replication might cause partial aneuploidy. This has usually deteriorating organisms, aneuploidy is associated with a...

EB - Genetika a molekulární biologie

  • 2015 - 2019
  • 7 214 tis. Kč
  • 7 214 tis. Kč
  • GA ČR
Project

Maternal ageing effect on activities of major protein kinases regulating mammalian meiosis. (GAP502/10/0944)

Chromosomal aneuploidy is the major cause of premature abortions in humans. Most of the chromosomal abnormalities have been shown to be of maternal origin of chromosomal aneuploidy. Although predisposition...

EB - Genetika a molekulární biologie

  • 2010 - 2013
  • 3 628 tis. Kč
  • 3 628 tis. Kč
  • GA ČR
Project

Algoritm of ultrasonogtaphical fetal markers in relationship to chromosomal aneuploidies (GA302/95/1235)

EB - Genetika a molekulární biologie

  • 1995 - 1997
  • 1 809 tis. Kč
  • 1 809 tis. Kč
  • GA ČR
Project

Investigations into aneuploides in gametes and embryos of farm animals using the in situ fluorescence hybridization technique (GA523/98/0261)

of aneuploidies of chromosomes in early bovine embryos and to test its applicability tooocytes. of fluorescence in situ hybridisation (FISH) as a method of investigation of chromosomal differences in the numbers of ane...

EB - Genetika a molekulární biologie

  • 1998 - 2000
  • 3 749 tis. Kč
  • 3 569 tis. Kč
  • GA ČR
Project

Role of the regulatory factors acting at 3’end of mRNA in correct progression of mammalian oocyte meiotic maturation. (GA15-22765S)

of chromosome segregation errors leading to increased rate of abortions and developmental disorders. Most of the chromosomal abnormalities are of maternal origin and higher maternal age seems to be responsible for increase in the f...

EB - Genetika a molekulární biologie

  • 2015 - 2019
  • 6 781 tis. Kč
  • 6 781 tis. Kč
  • GA ČR
Project

The changes in chromatin structure during meiotic maturation of pig oocytes correlation to chromosomal aneuploidy (GA204/06/1297)

complex subunits, as well as Aurora B kinase in the process of chromosome condensation samples will be used for the study of possible occurrence of aneuploidy and other chromosomal abnormalities in females from our breed o...

ED - Fyziologie

  • 2006 - 2008
  • 2 308 tis. Kč
  • 2 308 tis. Kč
  • GA ČR
Project

Quantitative fluorescent PCR in prenatal and postnatal diagnosis of aberrations of chromosome number and structure,and of their parental origin. (NE6411)

The aim of the project is to improve the screening and the diagnostic possibilities of chromosomal anomalies since the ITS to the end of IIIrd trimesters QFPCR detection of the most frequent aneuploidies and interstitial deletions o...

FD - Onkologie a hematologie

  • 2000 - 2002
  • 1 722 tis. Kč
  • 1 722 tis. Kč
  • MZ
Project

The detection of mosaicism in mouse embryos (GPP502/12/P785)

Chromosome abnormalities are presented in human and animal embryos and have individual. Besides chromosomes abnormalities coming from oocyte or sperm, such errors, when individual blastomeres bear different chromosome set. ...

EB - Genetika a molekulární biologie

  • 2012 - 2014
  • 1 724 tis. Kč
  • 1 724 tis. Kč
  • GA ČR
Project

Chromosomal disorders and chromatin integrity in bull sperm (GP523/07/P077)

analysis. The impact of frequency of aneuploidies in selected sperm chromosomes on frequency of aneuploidies in embryos from selected bulls will be investigated. Results......

EB - Genetika a molekulární biologie

  • 2007 - 2009
  • 735 tis. Kč
  • 735 tis. Kč
  • GA ČR
Project

Examination of DNA instability in gametes, embryos and somatic cells following oncological therapy for improvement of reproductive success in treated patients. (NT13770)

or mitotic spindle, which leads to chromosomal aneuploidies. Single-cell arrayCGH will detect deletions, duplications and aneuploidies, thereby assuring efficacious in chromosomal aberrations of somatic cells, gam...

FD - Onkologie a hematologie

  • 2012 - 2015
  • 9 783 tis. Kč
  • 9 783 tis. Kč
  • MZ
  • 1 - 10 out of 539