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129 (0,146s)

Project

Human urinary exosomes - the source of new biomarkers for the diagnosis and follow-up of kidney diseases (NV15-31662A)

The project will study new diagnostic and predictive biomarkers in urinary exosomes in patients with immune-based kidney diseases (lupus nephrititis and ANCA-associated vasculitis) and IgA nephropathy, Urinary exosomes contain proteins and nucleic ac...

FE - Ostatní obory vnitřního lékařství

  • 2015 - 2019
  • 7 500 tis. Kč
  • 7 441 tis. Kč
  • MZ
Project

Iron stores- relation to clinical manifestation of anemia - pathogenesis,diagnosis and treatment (IZ1918)

9F - 9

  • 1994 - 1996
  • 2 000 tis. Kč
  • 3 150 tis. Kč
  • MZ
Project

Longitudinal trends in major cardiovascular risk factors and their predictive value in a population random sample, Czech post-MONICA study (NV15-27109A)

The Czech Republic (CR) is a country with high CV mortality decreasing since 1985. Using the validated IMPACT mortality model, more than half of the substantial fall in CHD mortality in the CR was attributable to reduction in major CV risk factors; i...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2015 - 2019
  • 16 648 tis. Kč
  • 16 648 tis. Kč
  • MZ
Project

Unconventional Methods of Ventilation in Therapy of RDS of Very Low Birth Weight Newborns and the Comparison of Conventional and Unconventional Methods of Venti (IZ3178)

FG - Pediatrie

  • 1995 - 1997
  • 2 448 tis. Kč
  • 2 427 tis. Kč
  • MZ
Project

Heart failure in patients with advanced chronic kidney disease improvement of diagnostics, understanding of less explored mechanisms (CZecking Heart Failure in Chronic Kidney Disease trial) (NU22-02-00014)

Most patients with advanced chronic kidney disease (CKD) are affected by cardiovascular complications. Heart failure (HF) is the main cause of death in this population. The main aim of this project is to improve HF diagnostics in a middle-sized obse...

Cardiac and Cardiovascular systems

  • 2022 - 2025
  • 8 297 tis. Kč
  • 8 297 tis. Kč
  • MZ
Project

Identification and characterization of genetic factors contributing to inherited tubulointerstitial kidney disease (NV17-29786A)

Autosomal dominant tubuloinsterstitial kidney diseases (ADTKD) are characterized by autosomal dominant inheritance, pathologic tubular changes and interstitial fibrosis resulting in slowly progressive chronic kidney disease. There are four major cond...

EB - Genetika a molekulární biologie

  • 2017 - 2020
  • 11 703 tis. Kč
  • 11 703 tis. Kč
  • MZ
Project

New pharmacological approaches for the treatment of heart failure with reduced ejection fraction combined with chronic kidney disease. (NU23J-02-00015)

Heart failure with reduced ejection fraction (HFrEF) and chronic kidney diseases (CKD) represent serious medical problems and especially when combined, patients have extremely poor prognosis in the term of survival rate. Therefore, new treatment stra...

Cardiac and Cardiovascular systems

  • 2023 - 2026
  • 6 842 tis. Kč
  • 6 842 tis. Kč
  • MZ
Project

Immunohistochemistry of cellular infiltrate and vascular changes in biopsy of allotransplanted kidney,and its importance in clinical diagnosis (IZ2602)

FP - Ostatní lékařské obory

  • 1995 - 1997
  • 953 tis. Kč
  • 953 tis. Kč
  • MZ
Project

Identification and characterization of genetic factors contributing to inherited tubulointerstitial kidney disease II (NU21-07-00033)

Autosomal dominant tubuloinsterstitial kidney diseases (ADTKD) refers to a clinical syndrome characterized by autosomal dominant inheritance, pathologic tubular changes and interstitial fibrosis resulting in slowly progressive chronic kidney disease....

Human genetics

  • 2021 - 2024
  • 12 754 tis. Kč
  • 12 754 tis. Kč
  • MZ
Project

The role of renal dysfunction in the progression of congestive heart failure and its potential clinical implications preclinical studies in animal models (NV18-02-00053)

Congestive heart failure (CHF) presents a serious medical problem and when combined with the development of renal dysfunction, long term prognosis and survival rate are extremely poor. Therefore, new treatment strategies that would prevent developmen...

Cardiac and Cardiovascular systems

  • 2018 - 2021
  • 9 499 tis. Kč
  • 9 499 tis. Kč
  • MZ
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