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1 181 (0,119s) •

Project

Photochemical Catch and Release Strategy Towards Novel Molecular Switches and Bioorthogonal Reactions (GA22-20319S)

in the last decades, use click reactions for covalent attachment of an actuating molecule) sequential combination of click and clip processes for precise regulation of biochemical novel molecular systems for the catch and release s...

Organic chemistry

  • 2022 - 2024
    • •
  • 8 075 tis. Kč
    • •
  • 7 092 tis. Kč
    • •
  • GA ČR
Project

Interpenetrating polyacetylene based polymeric networks prepared by "click" chemistry (GA203/09/0803)

copper catalyzed dipolar cycloaddition of Huisgen type "click chemistry". Resulting graft polymers with highly conjugated polymer backbone and several grafts "clicked......

CD - Makromolekulární chemie

  • 2009 - 2011
    • •
  • 2 026 tis. Kč
    • •
  • 2 026 tis. Kč
    • •
  • GA ČR
Project

New metabolic pathways of lipid trafficking (LUAUS24040)

through endosomes using alkyne-azide click chemistry. 1.2 Investigate ceramide of metabolic cycling between triacylglycerols and fatty acids using click chemistry. 2.2......

Biochemistry and molecular biology

  • 2024 - 2027
    • •
  • 10 122 tis. Kč
    • •
  • 10 122 tis. Kč
    • •
  • MŠMT
Project

Nanoliposomes for development of recombinant vaccines and targetted immunotherapeutics (GAP304/10/1951)

for the construction of nanoliposomes. Click-chemistry and metallochelating bonds will by applied, organic chemistry, proteomics and advanced ultrastructural methods for the preparation......

EC - Imunologie

  • 2010 - 2013
    • •
  • 10 879 tis. Kč
    • •
  • 10 879 tis. Kč
    • •
  • GA ČR
Project

Templated synthesis and product characterization focused at development of potent and selective ligands of c-myc G-quadruplex (GA17-04393S)

azide-alkyne click chemistry which has not been studied in this context-alkyne click chemistry will enable discovery of novel binders. Starting point......

CC - Organická chemie

  • 2017 - 2018
    • •
  • 4 135 tis. Kč
    • •
  • 2 994 tis. Kč
    • •
  • GA ČR
Project

Synthesis and characterization of bioactive surfaces via controlled radical polymerizations and click chemistry (GAP106/12/1451)

to protein resistant brushes via copper free click chemistry....

CD - Makromolekulární chemie

  • 2012 - 2014
    • •
  • 6 564 tis. Kč
    • •
  • 6 564 tis. Kč
    • •
  • GA ČR
Project

Electron Attachment to Triazoles and Their Complexes (GF25-16240L)

Triazole is a common product of click chemistry. Consequently, triazoles are the usual motive in many commercially produced chemicals. We will study the attachment of low-energy electrons to different derivatives of 1,2,3-/1,2,4-tri...

Atomic, molecular and chemical physics (physics of atoms and molecules including collision, interaction with radiation, magnetic resonances, Mössbauer effect)

  • 2025 - 2028
    • •
  • 6 496 tis. Kč
    • •
  • 6 496 tis. Kč
    • •
  • GA ČR
Project

Effective Targeted Therapies Development and Commercialization of Modern Antibody Conjugation Approaches (TQ15000018)

This project aims to enhance and streamline the manufacturing process of antibody-drug conjugates (ADCs) by using cutting-edge technologies based on click reactions. Introducing a novel conjugation step that is both quicker and more efficien...

Organic chemistry

  • 2025 - 2026
    • •
  • 5 744 tis. Kč
    • •
  • 4 526 tis. Kč
    • •
  • TA ČR
Project

INJECTABLE POLYPEPTIDE BASED HYDROGELS MIMICKING THE DYNAMIC PROCESSES IN EXTRACELLULAR MATRIX (GA18-03224S)

crosslinked reaction. The biomimetic molecules binding will be achieved using click chemistry and by non-covalent interaction between peptides (e.g. a coiled-coil......

Bioproducts (products that are manufactured using biological material as feedstock) biomaterials, bioplastics, biofuels, bioderived bulk and fine chemicals, bio-derived novel materials

  • 2018 - 2022
    • •
  • 4 367 tis. Kč
    • •
  • 4 292 tis. Kč
    • •
  • GA ČR
Project

Materials with nanostructured surface for biomedical applications (GA16-02702S)

-repulsive sublayer, with alkyn-azide click chemistry reactions (CuAAC) for binding...

CD - Makromolekulární chemie

  • 2016 - 2018
    • •
  • 6 111 tis. Kč
    • •
  • 5 574 tis. Kč
    • •
  • GA ČR
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