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3 (0,091s)

Project

Molecular mechanisms of nuclear structure formation (LTAUSA18103)

coilin and assembly of Cajal bodies. We will also test our prediction that incomplete is divided into three particular aims: 1. To determine a role of coilin N-terminal domain for formation of Cajal bodies 2. To determine a role of...

Cell biology

  • 2019 - 2022
  • 5 459 tis. Kč
  • 5 459 tis. Kč
  • MŠMT
Project

Molecular mechanisms of snRNP quality control (GA24-11157S)

of snRNP biogenesis. We will also test the hypothesis that coilin is a factor that specifically controls final steps of snRNP assembly. We will explore whether coilin will investigate the molecular details of coilin intera...

Biochemistry and molecular biology

  • 2024 - 2026
  • 12 007 tis. Kč
  • 11 830 tis. Kč
  • GA ČR
Project

Spliceosomal snRNP assembly and surveillance in Drosophila melanogaster (LH14033)

The main aim of this project is to characterize and compare key mechanisms that control formation of snRNPs in human and fruit fly. We will mainly concentrate on newly imported snRNPs to the nucleus and the role of coilin and Cajal bodies

EB - Genetika a molekulární biologie

  • 2014 - 2016
  • 1 769 tis. Kč
  • 1 769 tis. Kč
  • MŠMT
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