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12 (0,097s)

Project

Signaling pathways and genes regulating gonadotropin-induced maturation of pig cumulus-oocyte complexes (GAP502/11/0593)

activated in cumulus-oocyte complexes (COCs) during resumption of meiosis in vitro in vitro. The gonadotropins induce synthesis of EGF-like peptides in cumulus cells resumption of oocyte meiosis, expansion of cumulus cells...

ED - Fyziologie

  • 2011 - 2014
  • 9 315 tis. Kč
  • 9 315 tis. Kč
  • GA ČR
Project

Role of luteinizing hormone receptors in maturationof pig oocyte-cumulus cell complexes in vivo and in vitro (GA523/04/0574)

In preovulatory follicles, oocytes resume meiosis, cumulus cells undergo of luteinizinghormone (LH). However, in cumulus cells, a lack of very low concentration of specific affects expression of specific genes in cumulus ce...

ED - Fyziologie

  • 2004 - 2006
  • 2 850 tis. Kč
  • 2 230 tis. Kč
  • GA ČR
Project

Relationship between Meiotic Competence and Cumulus Expansion in Mammalian Oocytes The Role of Cumulus Expansion Enabling Factor (IAA745401)

FR - Farmakologie a lékárnická chemie

  • 1994 - 1996
  • 511 tis. Kč
  • 841 tis. Kč
  • AV ČR
Project

Effect of epidermal growth (EGF) and meiosis activating sterols (MAS) on cumulus expansion and resumption of meiosis in the pig (GA524/98/0231)

differentiate into two populations: mural granulosa cells and cumulus cells, surrounding major events occur in the oocyte-cumulus cell complex. First, the oocyte arresteat, the cumulus cells undergo expansion or mucificati...

ED - Fyziologie

  • 1998 - 2000
  • 2 224 tis. Kč
  • 1 835 tis. Kč
  • GA ČR
Project

Cumulus oophorus - early embryo relationships in in vitro cultivation (IZ2703)

9F - 9

  • 1995 - 1996
  • 286 tis. Kč
  • 286 tis. Kč
  • MZ
Project

Potential of EGF-like peptides and synthetic analogues of cAMP to enhance developmental capacity of pig oocytes cultured in vitro (GA523/08/0111)

in pig oocyte-cumulus complexes (OCCs) during resumption of meiosis and to design and cumulus cellsunder in vivo and in vitro conditions. Signaling pathways and genes activated in cumulus cells by EGF-like peptides will be...

ED - Fyziologie

  • 2008 - 2010
  • 2 444 tis. Kč
  • 2 444 tis. Kč
  • GA ČR
Project

Immunodetection of structural constituents in cumulus -extracellular matrix, that are crucial for female fertility. (GA305/05/0960)

The formation of the hyaluronan-rich cumulus extracellular matrix (ECM) is crucial for female fertility and accompanied by a transesterification reaction in which the heavy chains (HC) of inter-+-trypsin inhibitor (I+I)-related proteins in t...

FK - Gynekologie a porodnictví

  • 2005 - 2007
  • 2 027 tis. Kč
  • 1 551 tis. Kč
  • GA ČR
Project

Interplay between an oocyte and granulosa cells Secretion of paracrine factors enablig expansion of cumulus cells (IAA5045102)

. In addition, secretion of paractine factors enabling expansion of cumulus cells...

FK - Gynekologie a porodnictví

  • 2001 - 2003
  • 3 084 tis. Kč
  • 2 411 tis. Kč
  • AV ČR
Project

Identification of Peroxisomes and Their Role in Germinal Cells Protection From Free Oxygen Radicals in Human In Vitro Fertilization (NH5164)

The aim this project is to identify peroxisomes in human cumulus-oocyte complexes by meons of electron microscopy and cytochemical demonstration of catalase and their reactions on various levels of free oxygen radicalis in cultive environmen...

FK - Gynekologie a porodnictví

  • 1999 - 2001
  • 1 538 tis. Kč
  • 1 513 tis. Kč
  • MZ
Project

Advanced methods of evaluation of male ejaculate and human sperm separation techniques (LUC23009)

chemotaxis of human sperm to progesterone, charged by human cumulus cells. Recently, a 3D cumulus cell culture system was developed in our laboratory, thanks to which......

Obstetrics and gynaecology

  • 2023 - 2025
  • 2 271 tis. Kč
  • 2 271 tis. Kč
  • MŠMT
  • 1 - 10 out of 12