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9 (0,133s)

Project

Cyklosporin A in the treatment of high - risk perforated keratoplasty (IZ3729)

FP - Ostatní lékařské obory

  • 1996 - 1998
  • 845 tis. Kč
  • 845 tis. Kč
  • MZ
Project

Cyklosporin in renal transplantation a risk factor for lipid matabolism (IZ3065)

FP - Ostatní lékařské obory

  • 1995 - 1997
  • 530 tis. Kč
  • 499 tis. Kč
  • MZ
Project

FK 506 after organs transplantation. (IZ3012)

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 1995 - 1997
  • 590 tis. Kč
  • 590 tis. Kč
  • MZ
Project

Cyclosporin nephrotoxicity in patients with autoimmune diseases - early diagnosis and monitoring (IZ3587)

FP - Ostatní lékařské obory

  • 1996 - 1998
  • 1 110 tis. Kč
  • 1 110 tis. Kč
  • MZ
Project

Effective immunosupressive treatment methods in patients with systemic lupus erytematodes and renal affection - lupus nephritis. (IZ2148)

9F - 9

  • 1994 - 1996
  • 540 tis. Kč
  • 810 tis. Kč
  • MZ
Project

CTLA-4 Ig prophylactic monotherapy and combination with anti-CD4 and anti-TCR in rat aortic allograft model (IZ3060)

9F - 9

  • 1995 - 1996
  • 227 tis. Kč
  • 227 tis. Kč
  • MZ
Project

Multidrug Resistance in Cancer Molecular, Celular and Clinical Aspects. (IZ4132)

The objective of the study is to elucidate the molecular,cellular and clinical aspects of multidrug resistance in cancer.We intend to evaluate the prognostic value of multidrug resistance in haematological and solid tissue malignancies. Further,we pl...

FD - Onkologie a hematologie

  • 1997 - 2001
  • 13 372 tis. Kč
  • 13 079 tis. Kč
  • MZ
Project

Plasma level of cyclosporine A and its metabolites and incidence of unwanted effects (hypertension, renal toxicity, graft rejection) in transplant patients. A Pk/Pd modelling. (OC B15.20)

Cyklosporine (CyA), the potent immunosupressive agent, is used in the prevention of graft rejection in bone marrow, solid organ transplantation, kidney, heart, heart-lung liver and pancreas. This drug exhibits a narrow therapeutic window bet...

FR - Farmakologie a lékárnická chemie

  • 1999 - 2003
  • 2 491 tis. Kč
  • 1 870 tis. Kč
  • MŠMT
Project

New Possibilities of TDM of Cyclosporine A and its Metabolites after kidney transplantation (1A8655)

Cyklosporin A (CsA) is the major imunossupresive drug for organ transplantations. Optimal immunossupresive effect so as reduction of adverse effects is done through terapeutic monitoring of CsA levels (TDM). Methods used for estimation of Cs...

FR - Farmakologie a lékárnická chemie

  • 2005 - 2009
  • 11 512 tis. Kč
  • 8 562 tis. Kč
  • MZ
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