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444 (0,146s)

Project

Immunoregulatory function of cytokine and chemokine receptors in pathogenesis and pathophysiology of blood diseases (NI5884)

Study of the expression of cytokine and chemokine receptors on normal and pathological cells and their importance in the immunology, pathogenesis and pathophysiology of blood diseases. The analytic approach for the detection of the main ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2000 - 2002
  • 3 695 tis. Kč
  • 3 335 tis. Kč
  • MZ
Project

genetic analysis of cytokine production in Leishmania major infected mice (GP310/02/P141)

as a model pathology mediated by cytokine imbalance. The cytokine network is important tool of immune system and signals coming from cytokine receptors are critical determinantof immune reactions. Cytokine product...

EB - Genetika a molekulární biologie

  • 2002 - 2002
  • 465 tis. Kč
  • 246 tis. Kč
  • GA ČR
Project

Cytokine regulations of intestinal epithelial cell functions (1P05ME783)

study of cytokine impact on gene expression of enzymes of intestinal cells...

ED - Fyziologie

  • 2005 - 2008
  • 1 516 tis. Kč
  • 1 053 tis. Kč
  • MŠMT
Project

HLA polymorphism and polymorphism of cytokine genes in pemphigus vulgaris (MEB080892)

Research aim of the project is to investigate gene polymorphism (single nucleotide polymorphisms), particularly of TH2 cytokines (IL-4, IL-5, IL-6) and proinflammatory cytokines (IL-1, TNF, IFN-γ) in Slovak patients with pemphi...

EE - Mikrobiologie, virologie

  • 2008 - 2009
  • 24 tis. Kč
  • 24 tis. Kč
  • MŠMT
Project

Th1/Th2 cytokine gene polymorphisms in patients with idiopathic pulmonary fibrosis. Correlation with gene expression and cytokine production in bronchoalveolar lavage fluid and with clinical (NR9131)

of these patients to investigate gene polymorphism of large spectrum of Th1 and Th2 cytokines).We will try to find and identify the polymorphisms of cytokines that are likely to be responsible for a development of IPF.We will compa...

EB - Genetika a molekulární biologie

  • 2007 - 2009
  • 4 622 tis. Kč
  • 4 539 tis. Kč
  • MZ
Project

DOES ANY SPECIFIC IMBALANCE IN CYTOKINES OF T HELPER CELL ORIGINE ASSOCIATE WITH CANCER AND ITS RESPONSE TO CYTOKINE-BASED THERAPY? (NC5571)

The significance of the changes in CD4+ T helper lymphocyte-derived cytokines and CD mononuclear cell profiles in cancer-associated immune impairment and response to cytokine-based immunotherapy of cancer.......

FD - Onkologie a hematologie

  • 1999 - 2001
  • 5 179 tis. Kč
  • 5 179 tis. Kč
  • MZ
Project

Hormonal regulation of leaf senescence in cereals - interactions of cytokinins and ethylene (GP522/02/D058)

of leaf senescence by cytokines specified in the main project (522/02/0503) to another plant hormone, ethylene. Whereas cytokines delay senescence ethylene exhibit theoppositeeffect. It has been shown that ethylene and cytokine...

GD - Hnojení, závlahy, zpracování půdy

  • 2002 - 2005
  • 1 998 tis. Kč
  • 737 tis. Kč
  • GA ČR
Project

The role of cytokines in protection effect of live vaccinal strains of Salmonella (GA524/05/2248)

of inflammatory cytokines. Better understanding of cytokine responses is conditio sine qua non gene deletion on cytokine levels in the small bowel and circulation the role of inflammatory cytokines in defence agai...

EC - Imunologie

  • 2005 - 2007
  • 2 160 tis. Kč
  • 2 160 tis. Kč
  • GA ČR
Project

Polymorphism in genes for chemotactic cytokines and their receptors in Slavonic patients with myocardial infarction (ME 856)

detailed analysis of DNA polymorphisms in genes for chemotactic cytokines and their receptores in patients wit myocardial infaction...

FP - Ostatní lékařské obory

  • 2006 - 2010
  • 1 459 tis. Kč
  • 1 459 tis. Kč
  • MŠMT
Project

Development of recombinant vaccinia viruses with cytokine genes for tumor therapy. (IZ4414)

The use of recombinant vaccinia virus(VV)carrying cytokine genes in tumour therapy.Replicating and nonreplicating VV recombinants with cytokine genes will be prepared. Biological propertttttties of recombinants and of recombinant pr...

FD - Onkologie a hematologie

  • 1997 - 1999
  • 7 226 tis. Kč
  • 5 265 tis. Kč
  • MZ
  • 1 - 10 out of 444