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8 (0,071s) •

Project

Adoptive Immunotherapy - ex vivo Generation of Lymphokines Activated Cytotoxic Cells and Their Clinical Applications. (IZ2945)

FD - Onkologie a hematologie

  • 1995 - 1997
    • •
  • 2 558 tis. Kč
    • •
  • 2 558 tis. Kč
    • •
  • MZ
Project

Gold and silver surfaces modified with functional derivatives of boron hydrides (IAA400320901)

Gold and silver polyhedral particles with narrow size distribution and average diameter ranging from micrometer to nanometer dimensions will be prepared and securely deposited on titanium containing substrates (Ti or its alloys). The particles assemb...

CA - Anorganická chemie

  • 2009 - 2011
    • •
  • 3 791 tis. Kč
    • •
  • 3 791 tis. Kč
    • •
  • AV ČR
Project

Betulinic acid derivatives, identification of mechanism of anticancer action based on expression profiling. (GP301/09/P433)

Czech Republic is a country with a relatively high rate of cancer. The unsatisfactory results of anticancer therapy to date and the narrow spectrum of targeted drugs require active search for compounds with novel mechanisms of antitumour action. Our ...

FR - Farmakologie a lékárnická chemie

  • 2009 - 2011
    • •
  • 1 167 tis. Kč
    • •
  • 1 167 tis. Kč
    • •
  • GA ČR
Project

Development of broad-spectrum disinfectants with enhanced virucidal activity (NU23-09-00334)

The recent coronavirus pandemic (SARS-CoV-2) is not the only rapidly spreading viral disease. Recently, diseases that we considered eradicated (measles, whooping cough) or diseases that we know more from tropical areas (eg monkeypox) have been increa...

Microbiology

  • 2023 - 2026
    • •
  • 10 006 tis. Kč
    • •
  • 10 006 tis. Kč
    • •
  • MZ
Project

A comprehensive in vitro, ex vivo and in vivo experimental study of an osteoinductive phosphate adhesive intended for the bonding of bone fractures and the performance of arthrodesis (NW24-08-00367)

The aging of the European population is associated with an increased incidence of bone fractures. As a result of osteoporosis, the estimated number of fractures will further increase by 25% to 4.5 million by 2025. In addition, fractures and bone defe...

Orthopaedics

  • 2024 - 2027
    • •
  • 15 188 tis. Kč
    • •
  • 15 188 tis. Kč
    • •
  • MZ
Project

Experimental development of new antibacterial compounds and assessment of their potential towards combination therapy (NU21-05-00482)

Bacterial infections are a problem that threatens the health of both individuals and whole society, even in economically developed countries. Many staphylococci (methicillin-resistant S. aureus, or coagulase-negative staphylococci resistant to glycop...

Medicinal chemistry

  • 2021 - 2024
    • •
  • 8 073 tis. Kč
    • •
  • 8 073 tis. Kč
    • •
  • MZ
Project

Development of novel compounds as tools to address unfavourable epidemiology of resistant fungal infections (NW24-05-00539)

An increasing incidence of systemic, invasive infections caused by microscopic fungi and their natural and acquired resistance, combined with a limited number of systemic antifungal drugs, represents a serious and escalating health problem worldwide....

Pharmacology and pharmacy

  • 2024 - 2027
    • •
  • 14 090 tis. Kč
    • •
  • 14 090 tis. Kč
    • •
  • MZ
Project

Pre-clinical study of non-platinum metalodrugs for lung cancer therapy (NU22-08-00236)

Lung cancer is the malignant tumour disease, that is, together with breast cancer, the most diagnosed cancer type world-wide, with about 11% of 19 million of new patients. Importantly, lung cancer is the most frequent cause of death within all cancer...

Organic chemistry

  • 2022 - 2025
    • •
  • 11 593 tis. Kč
    • •
  • 11 593 tis. Kč
    • •
  • MZ
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