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Projects

4 814 projects (0,168s)

Project

Comparison of dendritic cells from healthy volunteers, patients with monoclonal gammopathy and multiple myeloma according to their functional properties (NR8081)

The aim of project is analysis of function state of dendritic cells generated volunteers. The aim of project is finding of possible defects of dendritic cells result inhibitors from seras can be used to regenerate ...

EC - Imunologie

  • 2004 - 2006
  • 1 367 tis. Kč
  • 1 315 tis. Kč
  • MZ
Project

Glycobiological characterization of head and neck tumors (GP304/03/P027)

Dendritic cells represent the most potent antigen-presenting cells in the human reaction. The expression of dendritic cells in normal human squamous epithelia of dendritic cells focusing ...

EA - Morfologické obory a cytologie

  • 2003 - 2005
  • 738 tis. Kč
  • 738 tis. Kč
  • GA ČR
Project

Optimized dendritic cells loaded with universal tumor antigens as a potent individualized cancer vaccine (NS9871)

This study aims to prepare a clinical grade cancer vaccine based on optimized dendritic cells loaded with tumor associated antigens tailored for each individual patient.......

FD - Onkologie a hematologie

  • 2008 - 2011
  • 8 171 tis. Kč
  • 8 171 tis. Kč
  • MZ
Project

The ability of dendritic cells to stimulate the tumor specific immune response in patients with lymphoid malignancies (NR8092)

The ability of intranodally injected dendritic cells, pulsed with tetanus toxm toxoid or apoptotic tumor cells will be studied in 20-40 patients with chronic dendritic cells will be compared with a respons...

FD - Onkologie a hematologie

  • 2004 - 2006
  • 1 660 tis. Kč
  • 1 513 tis. Kč
  • MZ
Project

Induction of immunity against HPV16 E6/E7 oncogenes-induced tumours with peptide- and dendritic cell-based vaccines; immunotherapy of minimal residual tumour disease. (IAA500520605)

This project is focused on the analysis of the differences in the effectiveness of the antigen presentation by dendritic cells in healthy, tumour-bearing and surgically treated animals. Peptide-loaded dendritic cells

EC - Imunologie

  • 2006 - 2009
  • 3 329 tis. Kč
  • 3 329 tis. Kč
  • AV ČR
Project

Impact of the digestion and absorption processes on the final biological activity of diet phytonutrients real health added-value (8X20023)

reaching the targeted cells (such as ovarian cells, mononuclear and dendritic cells). 2 dendritic cells developed from CD14+ blood mononuclear cells and on human blood BDCA-1+ (CD1c+)

Cell biology

  • 2020 - 2022
  • 203 tis. Kč
  • 203 tis. Kč
  • MŠMT
Project

Follicular dentritic cells in non-Hodgkin lymphomas - diagnostic significance (NC6037)

Follicular dendritic cells remain partly preserved in some lymphomas.Their numbers,patterns of distribution and immunophenotype may be characteristic for different types of lymphomas,an thus can assist in differential diagnosis.......

FD - Onkologie a hematologie

  • 2000 - 2002
  • 606 tis. Kč
  • 585 tis. Kč
  • MZ
Project

Anti-tumour therapy - vaccination with dendritic cells in patients with metastatic renal cell carcinoma. Phase II clinical study. (NT11137)

on interleukin-12 producing autologous dendritic cells. University Cell Immunotherapy Center Control to produce dendritic cell vaccines for clinical application. VaccinePrognosis of patients with metastat...

FD - Onkologie a hematologie

  • 2010 - 2013
  • 5 619 tis. Kč
  • 5 619 tis. Kč
  • MZ
Project

Immunotherapy Using Different Tumor Antigens in The Treatment of Multiple Myeloma (NR8945)

The aim of this project is to find an optimal strategy of T cell stimulation using dendritic cells loaded with different myeloma antigens. Irradiated myeloma cells, myeloma mRNA or peptides derived from tumor assoc...

FD - Onkologie a hematologie

  • 2006 - 2009
  • 6 929 tis. Kč
  • 6 587 tis. Kč
  • MZ
Project

Evaluation of impact of phytonutrients on immune cells in 3D culture systems (8J23FR005)

The main objective of the project is to evaluate the effects of punicalagine and berberine on bovine dendritic cells functions. We will study cell proliferation. For this goal we have to set up in vitro conditions suitable ...

Cell biology

  • 2023 - 2024
  • 156 tis. Kč
  • 156 tis. Kč
  • MŠMT
  • 1 - 10 out of 4 814