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582 (0,216s) •

Project

NTpro-BNP - noninvasive marker of acute rejection in heart transplant recipients (NR8058)

1. Can the NTpro-BNP level be used as a noninvasive marker of allograft rejection after heart transplantation? 2. Does the NTpro-BNP profile (over time) reflect the regression of treated acute rejection episode? 3. May the donor´s N...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2004 - 2006
    • •
  • 3 226 tis. Kč
    • •
  • 3 219 tis. Kč
    • •
  • MZ
Project

The novel molecular biology methods in early diagnosis of acute and chronic rejection. Determination of gene expression within rejecting renal allografts. (NM7544)

Diagnosis of acute and chronic rejection of renal allograft using IL-6, IL-10, TNF-alpha, TGF-beta, RANTES, MCP-1 and CD3 gene expression (RT-PCR in real time and IL-10 genes on development of acute and chronic rejection after renal...

FJ - Chirurgie včetně transplantologie

  • 2003 - 2005
    • •
  • 3 342 tis. Kč
    • •
  • 3 321 tis. Kč
    • •
  • MZ
Project

Early diagnosis of chronic rejection in patients after kidney transplantation (ND6373)

Chronic rejection has long been the main problem in kidney transplantation. Its procedures are searched for. In 100 patients, correlation between chronic rejection will be investigated. In a group of patients with signs of chronic <...

FJ - Chirurgie včetně transplantologie

  • 2000 - 2002
    • •
  • 1 714 tis. Kč
    • •
  • 1 714 tis. Kč
    • •
  • MZ
Project

Antidotes against HLA antigens and their importance for formation of chronical rejection. (ME 669)

We presuppose,that we will be able to prove asotiation between occurrence of antisubstance against HLA antigens of donor and chronical rejection of kidneys graft.......

FJ - Chirurgie včetně transplantologie

  • 2003 - 2004
    • •
  • 1 494 tis. Kč
    • •
  • 609 tis. Kč
    • •
  • MŠMT
Project

HLA antibody monitoring after kidney transplantation and its contribution to the prediction of the antibody-mediated allograft rejection risk (NT13562)

antibody-mediated allograft rejection will be compared with the aim to evaluate rejection risk. Pre-transplant HLA antibody analysis might be useful for stratification of recipients into the groups with low/high rejection ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2012 - 2015
    • •
  • 4 879 tis. Kč
    • •
  • 4 879 tis. Kč
    • •
  • MZ
Project

Circulating microRNAs as non-invasive markers of graft rejection in patients after heart transplantation (NV16-30537A)

rejection from those without rejection; different miRNA profile during cellular and antibody-mediated rejection will be identified. We will further validate panel of rejection without the need of economically and ...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2016 - 2020
    • •
  • 15 167 tis. Kč
    • •
  • 14 149 tis. Kč
    • •
  • MZ
Project

Diagnostics of antibody-mediated rejection after liver transplantation (NV16-27477A)

Antibody-mediated rejection (AMR) is a severe immunological complication transplants, the diagnosis of antibody-mediated (humoral) rejection is complicated as detected by the Luminex method for the diagnosis of antibody mediated

EC - Imunologie

  • 2016 - 2019
    • •
  • 8 138 tis. Kč
    • •
  • 8 138 tis. Kč
    • •
  • MZ
Project

Imunohistochemistry in graft biopses of transplanted kedney in children (NE6442)

Immunohistochemistry of the rejection nefropathy in transplanted kidney of children.Immunohistochemical proof of surface cell antigens of activated rejection infiltrate.Correlation of the results between adults and children patients...

FG - Pediatrie

  • 2001 - 2003
    • •
  • 883 tis. Kč
    • •
  • 876 tis. Kč
    • •
  • MZ
Project

Correlation of intrarenal pro-inflammatory genes with early subclinical rejection of transplanted kidney and long-term graft function (NR8897)

Detection of subclinical rejections in transplanted kidneys by the method of protocol biopsy at 3 months posttransplant and anti-rejection treatment Evaluation of detectedand successfully treated subclinical rejections and ...

FJ - Chirurgie včetně transplantologie

  • 2006 - 2009
    • •
  • 4 351 tis. Kč
    • •
  • 3 851 tis. Kč
    • •
  • MZ
Project

The role of nonspecific immunity in the process of corneal graft rejection, tolerance and failure (NI7531)

The kinetics of the phenotypic markers-expression of the cells of nonspecific immunity, as the effector cells of corneal graft rejection will be investigated. The emphasis will be paid to the role of macrophages, eosinophils and NK cells in ...

EC - Imunologie

  • 2003 - 2005
    • •
  • 1 908 tis. Kč
    • •
  • 1 908 tis. Kč
    • •
  • MZ
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