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11 (0,082s) •

Project

Evaluation of the distribution of dopamine D2 receptors with use of 123I - IBZM SPECT in lateralized and unilateral dystonias. (NF6355)

(A) symmetry of density of dopamine D2 receptors is investigated in patients with unilateral/lateralized dystonia (cervical dystonia) in relation to (a) symmetry of clinical and electrophysiologic values.......

FH - Neurologie, neurochirurgie, neurovědy

  • 2000 - 2002
    • •
  • 1 606 tis. Kč
    • •
  • 1 057 tis. Kč
    • •
  • MZ
Project

Pathophysiology of dystonia – role of gene-environment interaction and common pathophysiological pathways (8F20001)

and phenotypically relevant mouse models of genetically divergent dystonias (DYT1, DYT6, DYT25 dystonia in patients by identification of clinical biomarkers; c) support the current clinical diagnosis of dystonia by molecu...

Other medical science

  • 2020 - 2024
    • •
  • 5 217 tis. Kč
    • •
  • 5 217 tis. Kč
    • •
  • MŠMT
Project

Mechanism of focal dystonias (IZ3571)

FL - Psychiatrie, sexuologie

  • 1996 - 1998
    • •
  • 1 720 tis. Kč
    • •
  • 1 646 tis. Kč
    • •
  • MZ
Project

Cerebellum, cognitive dysfunction, and motor control and time estimation mechanisms in dystonia and schizophrenia. (NT13437)

response. Dystonia is caused by a failure of multiple functional circuits of basal...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
    • •
  • 7 088 tis. Kč
    • •
  • 7 088 tis. Kč
    • •
  • MZ
Project

Molecular pathology and pathophysiology of neurodegenerative diseases accompanied by movement disorders (NR9215)

I. The project is focused on the genetic analysis of selected neurological movement disorders - Parkinson`s disease, torsion dystonia, essential tremor, and spinal muscular atrophy. The molecular genetic analyses will provide insight into pa...

FH - Neurologie, neurochirurgie, neurovědy

  • 2007 - 2009
    • •
  • 7 099 tis. Kč
    • •
  • 7 093 tis. Kč
    • •
  • MZ
Project

Pathophysiological mechanisms of neuromodulation therapy in dystonia (NT12282)

The project is aimed at the study of the pathophysiological mechanisms of deep brain stimulation of the globus pallidus interna (GPi DBS) in dystonic patients. Using functional imaging (resting-state fMRI) and electrophysiological testing (single-pul...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2015
    • •
  • 6 385 tis. Kč
    • •
  • 6 385 tis. Kč
    • •
  • MZ
Project

Changes of sensorimotor system organization and activation following botulinum toxin injection in cervical dystonia patients (NV16-30210A)

Patients suffering from cervical dystonia (CD) are very often notably limited in working and social activities. Botulinum toxin (BoNT-A) is currently considered to be the one of the most effective therapeutic options. However, the complete m...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2019
    • •
  • 6 726 tis. Kč
    • •
  • 6 726 tis. Kč
    • •
  • MZ
Project

The use of deep-brain stimulation in treatment of Parkinson's disease and movement disorders (1A8629)

The projects aims to develop methods and indications of deep-brain stimulation (DBS) in Parkinson's disease and other movement disorders that cannot be controlled by classical pharmacotherapy. The effects of DBS on on motor and non-motor brain functi...

FH - Neurologie, neurochirurgie, neurovědy

  • 2005 - 2009
    • •
  • 12 956 tis. Kč
    • •
  • 12 582 tis. Kč
    • •
  • MZ
Project

Motor regulation and its therapeutical influencing (GA309/98/0490)

investigations of dystonia by treatment will be also studied....

FH - Neurologie, neurochirurgie, neurovědy

  • 1998 - 2000
    • •
  • 2 153 tis. Kč
    • •
  • 2 153 tis. Kč
    • •
  • GA ČR
Project

Extrapyramidal Diseases - Correlation of Morphological, Functional and Clinical findings (NR8937)

Selected patients with Parinson´s disease, progressive supranuclear palsy, multiple system atrophy, dystonia and age-matched controls will be examined by neurologist, neuropsychologist, and with magnetic resonance imaging (MRI). Examinations...

FH - Neurologie, neurochirurgie, neurovědy

  • 2006 - 2009
    • •
  • 5 837 tis. Kč
    • •
  • 5 400 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 11