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5 (0,119s)

Project

Regulation of translation during pig oocyte maturation (GA301/00/0781)

of translation seems to be eIF-4E, which is a part of the protein complex which recognizes the levelsof expression and the phosphorylation state of initiation factor eIF-4E (also eIF-4alpha), as well as eIF-4E bin...

FP - Ostatní lékařské obory

  • 2000 - 2002
  • 1 683 tis. Kč
  • 1 410 tis. Kč
  • GA ČR
Project

The characterization of metabolic pathways invoved in translational initiation during meiotic maturation and early embryonic development in cattle and pig (GA524/04/0104)

of the most important factors for initiation of translation seems to be eIF-4E initiation form bind eIF-4E and prevent the formation of eIF-4F complex and in such a way......

GG - Chov hospodářských zvířat

  • 2004 - 2006
  • 2 811 tis. Kč
  • 2 155 tis. Kč
  • GA ČR
Project

Deciphering molecular details of the stringent decoding of the AUG start codon during eukaryotic translation initiation. (GAP305/10/0335)

ribosome and initiation factors (eIFs). This proposal aims to reveal how that the latter subunits comprise a self-operating eIF3 module that in cooperation with eIFs......

EB - Genetika a molekulární biologie

  • 2010 - 2014
  • 7 008 tis. Kč
  • 7 008 tis. Kč
  • GA ČR
Project

eIF3 at the Tip of the AUG Recognition Process in Humans (GA24-10013S)

initiation factors (eIFs), which orchestrate the TIS recognition. Despite the great multisubunit eIF3 and its associated eIFs contribute to stringent selection of the TIS......

Biochemistry and molecular biology

  • 2024 - 2026
  • 13 443 tis. Kč
  • 13 443 tis. Kč
  • GA ČR
Project

Structure and function of the human translation initiation factor 3 (eIF3) and its associated eIFs. (GA14-05394S)

Translation is a fundamental process critically contributing to regulation of gene expression. Because most regulation occurs during the initiation phase, its mechanism has being extensively studied. The multisubunit initiation factor eIF3 is undispu...

EB - Genetika a molekulární biologie

  • 2014 - 2016
  • 7 395 tis. Kč
  • 7 395 tis. Kč
  • GA ČR
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