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2 187 (0,118s) •

Project

Be The Cure (7H12093)

The development of new therapeutic agents against RA and RA-like diseases; (2) the heterogeneous nature of human RA and RA-like diseases; (3) the need for new alignments between several animal models and the varian...

FE - Ostatní obory vnitřního lékařství

  • 2012 - 2016
    • •
  • 9 375 tis. Kč
    • •
  • 2 296 tis. Kč
    • •
  • MŠMT
Project

Role of a novel cytokine IL-40 in the pathogenesis of rheumatoid arthritis (NU21-05-00276)

in the early phases of RA development. Therefore, our objective is to analyse the levels), in patients with early RA and established RA and to assess the predictive value of IL-40 in the pathogenesis of <...

Rheumatology

  • 2021 - 2024
    • •
  • 9 430 tis. Kč
    • •
  • 9 430 tis. Kč
    • •
  • MZ
Project

Detection of activated ras oncogenes in non-small-cell lung carcinoma and in premalignant changes of the respiratory epithelium Use in early diagnosis and prev (IZ2290)

9F - 9

  • 1994 - 1996
    • •
  • 1 570 tis. Kč
    • •
  • 2 260 tis. Kč
    • •
  • MZ
Project

Early interactions of porcine immune systém with Salmonella (GA524/01/0917)

Early interactions of the bacterium Salmonella typhimurium with the immune system will be studied in vivo in germ-free piglets orally infected in sterile isolators. A virulent LT2 strain, a protective rough Ra mutant with modified l...

EC - Imunologie

  • 2001 - 2003
    • •
  • 2 964 tis. Kč
    • •
  • 1 560 tis. Kč
    • •
  • GA ČR
Project

Role of S100A11 (calgizzarin) in the pathogenesis of rheumatoid arthritis (NV15-34065A)

relation to inflammation and disease activity in RA. Our aim is to analyze the levels of S100A11 in patients with early and established RA and their relation to the laboratory and clinical markers and to the radiographic p...

FE - Ostatní obory vnitřního lékařství

  • 2015 - 2018
    • •
  • 7 320 tis. Kč
    • •
  • 7 320 tis. Kč
    • •
  • MZ
Project

The prediction of development of rheumatoid arthritis (NU22-05-00226)

individuals at RA-risk from healthy controls and patients with early RA. We hypothesizeRheumatoid arthritis (RA) is a chronic autoimmune disease considered (ACPA) and rheumatoid factors (RF) preceding the manifest...

Rheumatology

  • 2022 - 2025
    • •
  • 8 572 tis. Kč
    • •
  • 8 572 tis. Kč
    • •
  • MZ
Project

Predictive value of adipokines in rheuamtoid arthritis (NS10614)

Annotation I: Patients with early RA will be examined and regularly followed by physicians. Except routine laboratory parameters, x-rays will be performed at baseline molecules, matrix degrading enzymes and other molecules involved ...

FE - Ostatní obory vnitřního lékařství

  • 2009 - 2011
    • •
  • 6 816 tis. Kč
    • •
  • 6 816 tis. Kč
    • •
  • MZ
Project

Clinically suspect arhralgia characteristics of the preclinical phase of rheumatoid arthritis (NV17-32612A)

, are considered to be at high risk of progressing to rheumatoid arthritis (RA), usually within relate to subclinical joint inflammation as measured by MRI or ultrasound. Early therapeutic interventions in RA improve clinic...

FE - Ostatní obory vnitřního lékařství

  • 2017 - 2020
    • •
  • 7 324 tis. Kč
    • •
  • 7 324 tis. Kč
    • •
  • MZ
Project

The study of relation between the activity of type - V collagenase and level of s-ICAM1 and s-VCAM1 in sera and synovial fluids to the prognosis of rheumatoid arthritis (NK6332)

A study will be made of the content and activity of gelatinase B and the levels of the soluble forms of immunoglobulins ICAM-1 and VCAM-1 in the blood serum and in the synovial fluid of patients with early rheumatoid arthritis. In the materi...

FE - Ostatní obory vnitřního lékařství

  • 2000 - 2002
    • •
  • 1 831 tis. Kč
    • •
  • 1 831 tis. Kč
    • •
  • MZ
Project

Mutual interactions of various vasoactive systems, reactive oxygen species and G proteins in experimental hypertension (GAP304/12/0259)

It is evident that renin-angiotensin system (RAS), sympathetic nervous system in the pathogenesis of both human and experimental hypertension. Because mutual RAS-SNS-NO-ROS abnormalities. We shall study the effects of peripheral vs....

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2012 - 2015
    • •
  • 8 308 tis. Kč
    • •
  • 8 308 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 2 187