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8 (0,103s)

Project

Endophenotypes of psychotic disorders (NV15-28998A)

Endophenotypes are heritable markers associated with illness, state-independent and shared among patients and their healthy relatives. To identify individuals at risk investigated as a candidate endophenotype. In our research projec...

FL - Psychiatrie, sexuologie

  • 2015 - 2018
  • 9 404 tis. Kč
  • 9 404 tis. Kč
  • MZ
Project

GENETIC AND ENVIRONMENTAL FACTORS IN EATING DISORDERS. A NEW GENETIC APPROACHES AND ENDOPHENOTYPES (NT14094)

Genetic studies of eating disorders (AN, BN and BED), which have a multifactorial etiology, require a more precise phenotyping of various subtypes. Therefore, the authors propose to add refinement of characteristic endophenotypes (neurophysi...

FL - Psychiatrie, sexuologie

  • 2013 - 2015
  • 5 693 tis. Kč
  • 5 693 tis. Kč
  • MZ
Project

Microvascular abnormality as an endophenotype of schizophrenia (NV16-27243A)

fulfils the important criterion for an endophenotype - it should be found...

FL - Psychiatrie, sexuologie

  • 2016 - 2019
  • 5 704 tis. Kč
  • 5 704 tis. Kč
  • MZ
Project

THE ROLE OF PHOSPHOINOSITIDE PATHWAY IN SUSCEPTIBILITY TO BIPOLAR AFFECTIVE DISORDER (NR8564)

First, we will conduct association studies of identified mutations in PI pathway genes in a large sample of BD patients (N=250) and a corresponding number of population controls with similar Caucasian middle European ethnic background. Second, we wil...

FL - Psychiatrie, sexuologie

  • 2005 - 2009
  • 4 476 tis. Kč
  • 4 467 tis. Kč
  • MZ
Project

Early markers of bipolar disorder from genetic risk to first symptoms (NT13337)

Prospective observation of subjects at risk of developing bipolar disorder (the offspring of bipolar parents) The objective is to catch first psychopathology and stalk its development with purpose to identify clinical, neuropsychological and electrop...

FL - Psychiatrie, sexuologie

  • 2012 - 2015
  • 5 298 tis. Kč
  • 5 298 tis. Kč
  • MZ
Project

Neuroanatomical risk factor for bipolar disorder (NT13891)

The project follows up our previous magnetic resonance imaging (MRI) study with the affected, unaffected offspring of parents with bipolar disorder (BP) and healthy controls and consists of : 1) prospective study arm, in which we will aquire a second...

FL - Psychiatrie, sexuologie

  • 2012 - 2015
  • 4 769 tis. Kč
  • 4 769 tis. Kč
  • MZ
Project

Early-stage identification of schizophrenia subtypes using a multimodal biomarker fingerprints (NU22-04-00143)

, endophenotype in form of smooth pursuit eye movement (SPEM) dysfunction will allow us...

Psychiatry

  • 2022 - 2025
  • 13 169 tis. Kč
  • 13 169 tis. Kč
  • MZ
Project

Systems genetic approach for identifying genes predisposing to salt-sensitive hypertension in the rat (LUAUS25164)

system for genetic and correlation analyses of complex traits using endophenotypes...

Cardiac and Cardiovascular systems

  • 2025 - 2028
  • 5 172 tis. Kč
  • 5 172 tis. Kč
  • MŠMT
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