All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

43 (0,142s) •

Project

Structural and functional determinants of NMDA receptor trafficking (GP14-09220P)

the endoplasmic reticulum. The results of this proposal will bring new findings about...

EB - Genetika a molekulární biologie

  • 2014 - 2016
    • •
  • 2 218 tis. Kč
    • •
  • 2 218 tis. Kč
    • •
  • GA ČR
Project

Role of membrane domains of NR1 and NR2 subunits in the assembly and trafficking of the NMDA receptor to the cell surface (GAP303/11/0075)

to the formation of functional NMDA receptors and to the masking of endoplasmic reticulum...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2013
    • •
  • 4 160 tis. Kč
    • •
  • 4 160 tis. Kč
    • •
  • GA ČR
Project

Pulmonary stress and regeneration (GA23-06675S)

, and elucidation of molecular mechanisms coupled with endoplasmic reticulum regulating cell...

Cell biology

  • 2023 - 2025
    • •
  • 6 996 tis. Kč
    • •
  • 6 935 tis. Kč
    • •
  • GA ČR
Project

The role of endoplasmic reticulum stress in the pathogenesis of obesity-related inflammation in human adipose tissue (GAP301/11/0748)

effects of endoplasmic reticulum stress (ERS) on the pro-inflammatory activation...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2011 - 2014
    • •
  • 6 444 tis. Kč
    • •
  • 6 444 tis. Kč
    • •
  • GA ČR
Project

Cellular and organismal roles of the intramembrane rhomboid protease RHBDL4 (GA20-25331S)

Rhomboid intramembrane proteases regulate epidermal growth factor receptor signalling in Drosophila, but their main functions in mice and humans are probably different and remain poorly understood. The endoplasmic reticulum (ER) loc...

Cell biology

  • 2020 - 2022
    • •
  • 9 570 tis. Kč
    • •
  • 9 390 tis. Kč
    • •
  • GA ČR
Project

ORMDL family proteins in mast cell signaling (GA14-00703S)

Proteins of the ORMDL (orosomucoid-like) family are transmembrane proteins, which are located in membranes of endoplasmic reticulum (ER). Genetic association studies showed strong link of ORMDL3 with asthma and inflammatory diseases...

EC - Imunologie

  • 2014 - 2016
    • •
  • 7 485 tis. Kč
    • •
  • 7 485 tis. Kč
    • •
  • GA ČR
Project

The effect of endoplasmic reticulum stress on the immune status of tumors and the efficiency of immunotherapy in the treatment of ovarian and renal cell carcinoma (NU21-03-00539)

to as “endoplasmic reticulum (ER) stress” is a crucial inducer of inflammation, including tumor...

Oncology

  • 2021 - 2025
    • •
  • 11 789 tis. Kč
    • •
  • 11 789 tis. Kč
    • •
  • MZ
Project

Three-dimensional analysis of endoplasmic reticulum structure based on processing of images captured by 2-photon and confocal microscopy (KJB6011309)

We will test the applicability and efficiency of methods for estimating the length of ER tubules, their length density in cell, proportion of lamellar sheets in ER, mean size and size distribution of meshes in the ER net, characteristics of ER organi...

EA - Morfologické obory a cytologie

  • 2003 - 2005
    • •
  • 1 767 tis. Kč
    • •
  • 1 186 tis. Kč
    • •
  • AV ČR
Project

Intramembrane proteases of the rhomboid family in the secretory pathway of mammalian cells substrate repertoire, specificity, biological roles and their inhibition (LK11206)

to endoplasmic reticulum (ER) stress induced apoptosis. ER stress response is an important...

EB - Genetika a molekulární biologie

  • 2012 - 2016
    • •
  • 20 171 tis. Kč
    • •
  • 20 171 tis. Kč
    • •
  • MŠMT
Project

Study of the endocytotic machinery via modification of viral-based nanoparticles (GA17-11397S)

in order to enhance a release of particles from endosomes/ lysosomes or endoplasmic reticulum and restrict the decoy pathway. The effect of these modifications......

EA - Morfologické obory a cytologie

  • 2017 - 2021
    • •
  • 8 082 tis. Kč
    • •
  • 7 950 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 43