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Projects

9 projects (0,142s) •

Project

Structural study of enterovirus replication in situ (GX19-25982X)

enteroviruses deliver their genomes into the cell cytoplasm; (2) whether enterovirusViruses from the genus Enterovirus, including coxsackieviruses and rhinoviruses, cause billions of infections every year. However, no anti...

Virology

  • 2019 - 2023
    • •
  • 49 410 tis. Kč
    • •
  • 49 410 tis. Kč
    • •
  • GA ČR
Project

Longitudinal observation of enterovirus RNA quantity in stools of infants with the highest genetic risk of Type 1 diabetes mellitus (GP301/02/D080)

the first year of life and tested for enteroviruses. Exposure to enterovirus infectionEnterovirus infection is one of the most suspected environmental triggers for developing a new method for detection and quantification o...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2004
    • •
  • 596 tis. Kč
    • •
  • 596 tis. Kč
    • •
  • GA ČR
Project

Childhood-onset diabetes in sub-Saharan Africa genetic and virological findings in Nigeria, and their comparison to European populations (NV15-31426A)

Enterovirus is suspected from participation in the type 1 diabetes aetiology, yet available studies are mostly limited to Caucasian populations living in the temperate climate. Nothing is known on populations living in the sub-Saharan tropic...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015 - 2018
    • •
  • 7 040 tis. Kč
    • •
  • 7 040 tis. Kč
    • •
  • MZ
Project

Detection and characterization of porcine teschoviruses and enteroviruses in pig breeding in the Czech Republic (GP524/09/P195)

The principle of the project is detection, isolation and genotyping of porcine picornaviruses in pig breeding in the Czech Republic.  Genus Porcine enterovirus (PEV) was reclassified according to genetic analyses as follows: Teschovirus (PTV...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2009 - 2011
    • •
  • 1 280 tis. Kč
    • •
  • 1 280 tis. Kč
    • •
  • GA ČR
Project

Selected picornaviruses in the pathogenesis of islet autoimmunity and type 1 diabetes (NT11465)

Type 1 diabetes arises from autoimmune insulitis that is initiated in genetically predisposed individuals by yet unknown environmental triggers. Enteroviruses belong to the suspected agents. The project utilizes samples from the Norwegian wi...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2010 - 2014
    • •
  • 7 121 tis. Kč
    • •
  • 7 121 tis. Kč
    • •
  • MZ
Project

Structural determinants of hijacking of the host ACBD3 protein by bovine and porcine picornaviruses (GJ17-07058Y)

picornaviruses from the Enterovirus and Kobuvirus genera. Particularly, we aim to perform...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2017 - 2019
    • •
  • 4 518 tis. Kč
    • •
  • 4 518 tis. Kč
    • •
  • GA ČR
Project

*Research and development of diagnostic kits for laboratory medical usage (FR-TI1/478)

*Molecular biology penetrated health service by innovations of diagnostic methods. Above all, it is DNA diagnostics that is used for the analysis of infectious microorganisms in clinical material. The aim of proposed project is the research, developm...

EE - Mikrobiologie, virologie

  • 2009 - 2012
    • •
  • 5 886 tis. Kč
    • •
  • 2 644 tis. Kč
    • •
  • MPO
Project

Protein tyrosine phosphatases in regulation of the immune system of diabetic patients (GAP301/12/1686)

Aberrant activation of immune cells is repeatedly recorded in patients with both, type I. and II. diabetes mellitus. Despite of the recent findings, above all on the role of enterovirus infections in the onset of type I. diabetes, the mechan...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2012 - 2014
    • •
  • 4 983 tis. Kč
    • •
  • 4 983 tis. Kč
    • •
  • GA ČR
Project

Infections in the pathogenesis of type 1 diabetes The MIDIA study (7F09015)

Type 1 diabetes is caused by organ specific autoimmunity resulting from gene-environmental interactions. The main goal of the pediatric diabetes research, including our project, is to improve the quality of life of children with diabetes or their fam...

EB - Genetika a molekulární biologie

  • 2009 - 2009
    • •
  • 253 tis. Kč
    • •
  • 253 tis. Kč
    • •
  • MŠMT
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