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2 120 (0,334s) •

Project

Delivery of Polyomavirus genomes into the cell nucleus and interactions of their structural proteins in host cells (GA13-26115S)

and mechanism of uncoating and delivery of viral genomes into the cell nucleus are still and to contribute to understanding the mechanism of delivery of viral genomes into the cellPolyomaviruses, small ...

FN - Epidemiologie, infekční nemoci a klinická imunologie

  • 2013 - 2017
    • •
  • 7 539 tis. Kč
    • •
  • 7 539 tis. Kč
    • •
  • GA ČR
Project

Nuclear phase of polyomavirus infection virus restriction and infection establishment. (GA19-14445S)

) trafficking to the cell nucleus and sensing its genome by DNA sensors will be to reveal how viral proteins affect nuclear lamina and matrix. Early after PyV genomes enter the nucleus, they appear in the ...

Virology

  • 2019 - 2022
    • •
  • 10 275 tis. Kč
    • •
  • 10 271 tis. Kč
    • •
  • GA ČR
Project

Large scale organization of chromatin (GA304/01/0729)

The cell nucleus represents the place where genomic DNA is accommodated. As the linear DNA length of a mammalian genome may be several meters and the diameter of the nucleus is only 10-15 um several levels of chrom...

EA - Morfologické obory a cytologie

  • 2001 - 2003
    • •
  • 5 749 tis. Kč
    • •
  • 4 671 tis. Kč
    • •
  • GA ČR
Project

How plant transposable elements contribute to the genomic landscape and organization of interphase nucleus (GA21-00580S)

Transposable elements (TEs) are a significant part of the plant genome aspects of TE life in plant genomes, including age, waves of amplification, structural as the effect of these processes on the genome. We will analyze t...

Genetics and heredity (medical genetics to be 3)

  • 2021 - 2023
    • •
  • 10 014 tis. Kč
    • •
  • 9 852 tis. Kč
    • •
  • GA ČR
Project

Identification of novel antiviral targets in the nucleus of hepatitis B virus infected cells (GN24-11554O)

Chronic hepatitis B virus (HBV) infection is a major public health problem affecting approximately 250 million people worldwide. HBV genome forms covalently closed circular DNA (cccDNA) and persists in the nucleus of hepatocytes in ...

Virology

  • 2024 - 2027
    • •
  • 5 273 tis. Kč
    • •
  • 5 273 tis. Kč
    • •
  • GA ČR
Project

Nuclear architecture in interspecific plant hybrids (GA17-13853S)

using 3D-FISH. We will evaluate the effect of parental genomes proportion on their positioning within the nucleus and track the dynamics in the genome organization duringThe plant cell nucleus is enclosed within t...

EB - Genetika a molekulární biologie

  • 2017 - 2019
    • •
  • 4 459 tis. Kč
    • •
  • 3 430 tis. Kč
    • •
  • GA ČR
Project

Mapping of the Viral Genomes of Pathogenic Bacteria Using Capillary Zone Electrophoresis for the Analysis of DNA Restriction Fragments (GA301/93/2138)

9H - 9

  • 1993 - 1995
    • •
  • 525 tis. Kč
    • •
  • 1 050 tis. Kč
    • •
  • GA ČR
Project

Identification of nuclear structures involved in gene expression (ME 279)

Different functions are spatially organized in cell nuclei and the genome in nuclei moves. However, what functions this movement has is not clear. The aim of this project is to define how the intranuclear movement relates to the principal bi...

EA - Morfologické obory a cytologie

  • 1998 - 2000
    • •
  • 429 tis. Kč
    • •
  • 278 tis. Kč
    • •
  • MŠMT
Project

Genetic sources of antiviral resistance in the domestic chicken (QL24010315)

to viral diseases (especially HPAI, IBV and IBDV). These variants will be sought by comparing the genomes of poultry breeds and related galliform birds. The antiviral effect of gene variants will be verified using pseudotyped v...

Husbandry

  • 2024 - 2028
    • •
  • 38 737 tis. Kč
    • •
  • 28 295 tis. Kč
    • •
  • MZe
Project

Genome reunions in plants from DNA to chromosomes and reverse (GAP501/10/0208)

when the diverged genomes become reunified in the nucleus. Large number of data of genomes are evolving rapidly and which remain constant. We will explore the fate of repeated DNA in cell nucleus. These directions...

GE - Šlechtění rostlin

  • 2010 - 2012
    • •
  • 2 973 tis. Kč
    • •
  • 2 973 tis. Kč
    • •
  • GA ČR
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