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349 (0,089s) •

Project

Role of virus-associated host-derived proteins in virus induced T cell dysfunction (GAP304/10/1161)

Herpetic viruses, such as VZV, and lentiviruses, such as HIV or SIV, are enveloped viruses, which infect CD4 T cells and cause transient (VZV) or progressive larger cell population. These viruses incorporate host-d...

EC - Imunologie

  • 2010 - 2016
    • •
  • 4 685 tis. Kč
    • •
  • 4 685 tis. Kč
    • •
  • GA ČR
Project

Mechanisms of antiviral and cytostatic effects of novel carbocyclic nucleoside analogs (GAP303/11/1297)

Carbocyclic nucleoside analogs containing norbornane moiety that have been prepared at IOCB represent new potential chemotherapeutics with significant activity against Coxsackie viruses (enteroviruses). These small, non-enveloped RN...

FR - Farmakologie a lékárnická chemie

  • 2011 - 2013
    • •
  • 4 137 tis. Kč
    • •
  • 4 137 tis. Kč
    • •
  • GA ČR
Project

Pathogenic effects of avian leukosis virus (ALV) infection molecular and genetic aspects (GA523/04/0489)

viruses of subgroup C (ALV-C), and to locate its position on the chicken viruses that areessential for induction of the wasting disease in chickens that the study of interactions between the receptor molecule and the C-envelope...

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2004 - 2006
    • •
  • 3 981 tis. Kč
    • •
  • 3 981 tis. Kč
    • •
  • GA ČR
Project

Simultaneous gene transcription and translation (GJ20-16013Y)

transcription and translation which are physically separated by the nuclear envelope. Nevertheless, some double-strand DNA viruses replicate in cytoplasmic factories of infected. We aim to test the hypothesis that replication of cy...

Biochemical research methods

  • 2020 - 2022
    • •
  • 9 834 tis. Kč
    • •
  • 9 834 tis. Kč
    • •
  • GA ČR
Project

Characterization of the cellular receptor Tvc and its role in the pathogenesis of avian leukosis viruses subgroup C-induced diseases (GA523/07/1282)

The aim of this project is to provide detailed characterization of the newly discovered chicken cellular receptor (Tvc), a member of the butyrophilin superfamily, which is employed by avian sarcoma-leukosis viruses of subgroup C (ASLV-C) to ...

GG - Chov hospodářských zvířat

  • 2007 - 2009
    • •
  • 4 690 tis. Kč
    • •
  • 4 690 tis. Kč
    • •
  • GA ČR
Project

Antiviral action of avian tetherin/BST2 (GA20-22063S)

Interaction of viruses with host factors, and particularly the characterization of direct antiviral restriction factors, constitute one of the main directions in recent virological research. We plan to investigate the orthologue of key mamma...

Virology

  • 2020 - 2022
    • •
  • 10 185 tis. Kč
    • •
  • 10 185 tis. Kč
    • •
  • GA ČR
Project

Crosstalk between transcription and translation (LL2008)

are physically separated by the nuclear envelope. Nevertheless, some double-strand DNA viruses replicate in cytoplasmic factories of infected eukaryotic cells, raising of cytoplasmic viruses in eukaryotic cells requires co...

Genetics and heredity (medical genetics to be 3)

  • 2020 - 2025
    • •
  • 48 953 tis. Kč
    • •
  • 48 953 tis. Kč
    • •
  • MŠMT
Project

Structure of retroviral particle and intracellular transport of its components. (LH12011)

Vectors expressing fluorescently tagged envelope and structural protein mutants of M-PMV altering assembly, transport or capsid release will be prepared. ?Live imaging? established in US laboratory will be employed for analysis of proteins. ...

EE - Mikrobiologie, virologie

  • 2012 - 2015
    • •
  • 1 990 tis. Kč
    • •
  • 1 990 tis. Kč
    • •
  • MŠMT
Project

Multiple criteria decision making and data envelopment analysis models as a support for economic decisions (GA402/03/1360)

support tool for economic decisions based on the combination of data envelopment analysis and multicriteria decision making models. Data envelopment analysis models the efficient frontier. The real world applications of the data

AH - Ekonomie

  • 2003 - 2005
    • •
  • 1 500 tis. Kč
    • •
  • 1 250 tis. Kč
    • •
  • GA ČR
Project

Hygric, Thermal and Mechanical Analysis of Innovated AAC-Based Building Envelope Systems Aiming at Durability Challenges (GA103/09/0016)

envelope systems based on autoclaved aerated concrete (AAC) using theoretical building envelopes will be measured first. Then, computational analysis of hygrothermal conditions in innovated envelope systems using long-term...

JN - Stavebnictví

  • 2009 - 2011
    • •
  • 3 720 tis. Kč
    • •
  • 3 720 tis. Kč
    • •
  • GA ČR
  • 1 - 10 out of 349