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2 083 (0,182s) •

Project

Enzymatic synthesis of bioactive glycosides (OC 170)

development of methodoly of application of glykosylazides as donors for transglykosilation reactions with glykosidazes....

CE - Biochemie

  • 2007 - 2007
    • •
  • 132 tis. Kč
    • •
  • 132 tis. Kč
    • •
  • MŠMT
Project

New enzymes and methods for chemoenzymatic synthesis of bioactive glycosides (GA203/01/1018)

Novel methods for enzymatic synthesis of bioactive glycosides based on aminosugars will be developed. New reaction conditions will be tested in enzymatic glycosylation to improve effectiveness of these reactions. New enzyme...

CE - Biochemie

  • 2001 - 2003
    • •
  • 6 664 tis. Kč
    • •
  • 3 794 tis. Kč
    • •
  • GA ČR
Project

New Enzymes and Selective Methods for Glycosidase-Catalysed Synthesis of Bioactive Glycosides and Glycomimetics (OC D25.002)

will be created. Novel methods for enzymatic synthesis of bioactive glycosidesNew enzymes for synthesis of oligoglycosides will be screened and characterized liquids, high salt concentrations. New reaction conditions will ...

CE - Biochemie

  • 2002 - 2006
    • •
  • 2 636 tis. Kč
    • •
  • 1 726 tis. Kč
    • •
  • MŠMT
Project

Combined chemical and enzymatic synthesis of complex multivalent glycoconjungates - ways to new materials and glycodrugs (OC 136)

preparation of glykomimetics, mainly based on polyaminoamidodendrimers (PAMAM) and kalixarens and elaborate procedure of enzyme modification...

CE - Biochemie

  • 2006 - 2010
    • •
  • 2 244 tis. Kč
    • •
  • 1 633 tis. Kč
    • •
  • MŠMT
Project

Enzymatic Peptide Synthesis in Nonconventional Media (GA203/95/0014)

CE - Biochemie

  • 1995 - 1997
    • •
  • 660 tis. Kč
    • •
  • 660 tis. Kč
    • •
  • GA ČR
Project

Chemoinformatics for glycosynthesis (LD13024)

The major drawback of enzymatic synthesis of oligosaccharides and glycoconjugates is a lack of understanding of factors determining which substrate is suitable for given enzyme and which products are preferred in a reaction with mul...

CE - Biochemie

  • 2013 - 2015
    • •
  • 1 305 tis. Kč
    • •
  • 1 305 tis. Kč
    • •
  • MŠMT
Project

Separation of N-acetylhexosamine-containing carbohydrates using physico-chemical and enzymatic methods (KJB400200601)

glycosylation)will be developed and optimised. Futhermore, complementary enzymatic methods for discrimination or selective synthesis of desired regioisomers will be investigated. Selective methods for regioselective synthesis

CE - Biochemie

  • 2006 - 2006
    • •
  • 398 tis. Kč
    • •
  • 398 tis. Kč
    • •
  • AV ČR
Project

Synthesis of novel derivatives and metabolites of quercetin-3-O-glucoside (GP14-14373P)

prohibitively high price. Our proprietary enzymatic procedure enables its preparation glucuronidation, sulfation and acylation chemical and enzymatic methods will be used. Since......

CC - Organická chemie

  • 2014 - 2016
    • •
  • 2 970 tis. Kč
    • •
  • 2 970 tis. Kč
    • •
  • GA ČR
Project

Synthetic oligofuranosides, their enzymatic preparation and the mode of cellular signalling (GP14-17194P)

of pathogen contamination and tedious low-yielding chemical synthesis. Using the glycosidase Araf51, we have recently demonstrated effectiveness of enzymatic approach......

EC - Imunologie

  • 2014 - 2018
    • •
  • 3 339 tis. Kč
    • •
  • 2 980 tis. Kč
    • •
  • GA ČR
Project

Enzymatic synthesis of multivalent glycoconjugates of natural and biologically active compounds. (LD13042)

The aim of the project is an elaboration of the methods of selective enzymatic glycosylation of multivalent glycomimetics (based on the thiourea-linked glycosides) and methodics of enzymatic glycosylation of the phenolic compounds. ...

CE - Biochemie

  • 2013 - 2015
    • •
  • 1 442 tis. Kč
    • •
  • 1 442 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 2 083