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9 590 (0,093s) •

Project

Plasma activities of intracellular enzymes in selected inborn errors of metabolism - suitability for diagnosis and for predicting responsiveness to therapy. (NT14159)

of plasma activity of selected intracellular enzymes involved in metabolism of amino acids, purines and fatty acids and verify the basic hypothesis that the enzymes the methods of determining the plasma activity o...

FG - Pediatrie

  • 2013 - 2015
    • •
  • 4 738 tis. Kč
    • •
  • 4 738 tis. Kč
    • •
  • MZ
Project

Functional role of oxysterols in plant photosynnthesis (GAP501/11/1650)

Small molecule enzyme activators enable us to better understand the endogenous principles of enzyme activation and their allosteric mechanisms. To activate an enzyme, they often bind to an alloste...

CE - Biochemie

  • 2011 - 2014
    • •
  • 5 850 tis. Kč
    • •
  • 5 850 tis. Kč
    • •
  • GA ČR
Project

Occurrence and properties of ligninolytic laccases and peroxidases in forest soils (KJB600200516)

of methods for estimation of enzyme activities and presence in soils. 2)Study of differentage, temporal and spatial variation of activity). 3) Purification of enzymes from of a ligninolytic fungus, relationships b...

EE - Mikrobiologie, virologie

  • 2005 - 2007
    • •
  • 1 652 tis. Kč
    • •
  • 1 652 tis. Kč
    • •
  • AV ČR
Project

Enzymes as aymmetric catalysts in transformations of organic molecules and biomolecules (OC D10.10)

The investigation of enzymic reactions will be provided under the non-classic). Its main goal will be focused on developing ways of enzymic synthesis of chiral compounds, both biologically active ones and their precursors. ...

CC - Organická chemie

  • 1998 - 2002
    • •
  • 4 195 tis. Kč
    • •
  • 2 095 tis. Kč
    • •
  • MŠMT
Project

Ferritin as a tool for enzymes-directed prodrug activation (NU21J-08-00043)

of enzymes for a catalytic activation of nontoxic prodrugs. In the project, advanced bio-nano delivery vehicles - ferritins for active transport of enzymes protective masking moieties will be investigated. Act...

Nano-materials (production and properties)

  • 2021 - 2024
    • •
  • 6 120 tis. Kč
    • •
  • 6 120 tis. Kč
    • •
  • MZ
Project

Development of methods for the simultaneous measurement of extracellular enzyme activities in soils and their use for the evaluation of soil function (QH72216)

The aim of the project is the standardisation and automatisation of enzyme activities in soils and their use for the evaluation of nonproductionn functions of soil in the interaction with soil productivity - the detection of functio...

DF - Pedologie

  • 2007 - 2011
    • •
  • 5 215 tis. Kč
    • •
  • 5 179 tis. Kč
    • •
  • MZe
Project

Synthesis of compounds affecting mitochondrial enzymes as potential drugs for Alzheimer disease (LD14009)

studying the modulator-enzyme interactions and structure-activity relationship modelling and structure-activity relationship determination of novel modulators of mitochondrial enzymes. These compounds have potenti...

CC - Organická chemie

  • 2014 - 2015
    • •
  • 1 364 tis. Kč
    • •
  • 1 364 tis. Kč
    • •
  • MŠMT
Project

Oriented immobilization of enzymes and antibodies using biospecific interactions (GA203/98/1231)

sterical accessibility of active site and enhanced stability of enzymes anantibodies immobilized in such a way. Enzyme reactors for activation of glycoprotein carbohydrate and their utilization forimmobilization o...

CC - Organická chemie

  • 1998 - 2000
    • •
  • 2 999 tis. Kč
    • •
  • 2 304 tis. Kč
    • •
  • GA ČR
Project

Complex cold adaptation study of enzymes on molecular level and their application in biotechnology (GA204/02/0843)

their genetic outfit and developed enzymes with relatively high activity at low temperatures. Detailed comparison of three-dimensional structures of cold-active ß-galactosidase of enzyme activity of ß-gal...

EB - Genetika a molekulární biologie

  • 2002 - 2004
    • •
  • 5 746 tis. Kč
    • •
  • 3 043 tis. Kč
    • •
  • GA ČR
Project

Digestive enzymes of Schistosoma_ New target for the treatment of parasitic (KJB400550516)

will be prepared by microseparation from the parasite and by expression as recombinant enzymes. The activation process will be analyzed for the protease zymogens processed to the mature enzymes. The activation pep...

CE - Biochemie

  • 2005 - 2007
    • •
  • 888 tis. Kč
    • •
  • 888 tis. Kč
    • •
  • AV ČR
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