All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

72 (0,128s) •

Project

Construction of recombinant mimotopes for induction of neutralizing antibodies against HIV-1 gp120 glycoprotein using high-affinity binders approach (NV15-32198A)

(bn-mAbs) recognizing Env glycans as a part of their epitopes provides the new opportunity for vaccine design. As the composite glycans-containing epitopes are less effective immunogens than protein epitopes, we propose to...

EC - Imunologie

  • 2015 - 2018
    • •
  • 6 200 tis. Kč
    • •
  • 6 200 tis. Kč
    • •
  • MZ
Project

Development of bioaffinity reactors for on-chip determination and analysis of epitopes with immunogenic or allergogenic potencial (GA203/05/0241)

for epitope screening of autoantigens and alergens and for estimation of epitope-antibody...

CB - Analytická chemie, separace

  • 2005 - 2007
    • •
  • 2 334 tis. Kč
    • •
  • 2 294 tis. Kč
    • •
  • GA ČR
Project

Monoclonal antibodies to COMP epitope mapping and use in diagnosis and prognosis of rheumatoid arthritis and osteoathritis (NK4887)

We will map the epitopes of four anti-COMP mAbs,characterize fragments of COMP in synovial fluid,develop two-antibody sandwich ELISA for COMP,and test prognostic value of developed assay on patients with OA and RA that will be followed for 3...

FP - Ostatní lékařské obory

  • 1998 - 2000
    • •
  • 3 744 tis. Kč
    • •
  • 3 296 tis. Kč
    • •
  • MZ
Project

The control of viremia by neutralizing antibodies and localization of neutralization epitopes of porcine circovirus 2 (GA524/06/1640)

epitopes. We plan to generate scFv antibodies against recombinant capsid protein in thecase of PCV-2 virus, the exact localization of neutralizing epitope(s) was never......

GJ - Choroby a škůdci zvířat, veterinární medicina

  • 2006 - 2008
    • •
  • 1 825 tis. Kč
    • •
  • 1 825 tis. Kč
    • •
  • GA ČR
Project

Impact of different topology of heterologous antigenic determinants in PVX-based plant viral vector on their expression level and immunogenicity (GAP501/12/1761)

the stability of heterologous epitopes produced in plants using a viral vector based. The ability of the PVX-based vector to support the expression of an epitope protein (CP) will be studied. We propose the production of the immuno...

EE - Mikrobiologie, virologie

  • 2012 - 2014
    • •
  • 6 967 tis. Kč
    • •
  • 6 793 tis. Kč
    • •
  • GA ČR
Project

Immunomodulation as a functional proteomics tool for cytokinin signaling study in Arabidopsis thaliana (GA521/09/1699)

tunedapproach to modulate protein activity and clarify its function. Monospecific epitopes or polyspecific epitope in same family of proteins instead of the whole proteins, could that blocking a single epitope may leave ot...

EB - Genetika a molekulární biologie

  • 2009 - 2012
    • •
  • 4 702 tis. Kč
    • •
  • 4 702 tis. Kč
    • •
  • GA ČR
Project

Mapping the surface epitopes of the gp135 glycoprotein of the Maedi- Visna virus (GA524/97/0312)

neutralising epitopes, rabbits will be immunised with aforementioned fusion proteins on tissue culture system. Mapping the epitopes of the envelope glycoprotein of the Maedi......

EE - Mikrobiologie, virologie

  • 1997 - 1999
    • •
  • 1 906 tis. Kč
    • •
  • 1 706 tis. Kč
    • •
  • GA ČR
Project

Non-replicative vectors for induction of specific cellular immune responses (GA310/98/0432)

Bordetella pertussis expressing foreign vaccinally important epitopes. This new non-replicative vector for inducing epitope-specific systemic and mucosal cellular epitope......

EB - Genetika a molekulární biologie

  • 1998 - 2000
    • •
  • 3 642 tis. Kč
    • •
  • 3 250 tis. Kč
    • •
  • GA ČR
Project

Characteristic features of immune response to wheat proteins in allergic and celiac patients (GA310/05/2245)

and activation;.4) identity IgE binding epitopes of wheat allergens including gliadins and to compare them with IgA binding epitopes of celiac patients, using epitope analysis......

EC - Imunologie

  • 2005 - 2007
    • •
  • 2 273 tis. Kč
    • •
  • 2 273 tis. Kč
    • •
  • GA ČR
Project

Fluorinated carbohydrates A valuable tool to study glycan-protein interactions and remodel cell-surface glycome (LTC20052)

, and for NMR epitope mapping; 1b) The synthesis of systematically deoxofluorinated by ELISA and ELLA assays; 2b) Epitope mapping of LacNAc, LacdiNAc......

Organic chemistry

  • 2020 - 2023
    • •
  • 4 119 tis. Kč
    • •
  • 4 119 tis. Kč
    • •
  • MŠMT
  • 1 - 10 out of 72