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53 (0,06s)

Project

Functionalization of piperidine moiety of ergoline skeleton of ergot alkaloids and their oligomerization - ways to better drug targetting (1P05OC073)

new attitudes to modification of ergot alkaloids (EA) mainly by functionalization of D-circle of ergoline skeleton...

CC - Organická chemie

  • 2005 - 2007
  • 1 283 tis. Kč
  • 893 tis. Kč
  • MŠMT
Project

Production of ergot alkaloids by parasitic and endophytic fungi (OC 835.30)

Screening for endophyte infected Czech ecotypes of agriculturally important grasses and analysis of toxic compounds produced by these endophytes. Analysis of ergot alkaloids in parasitic isolates of Claviceps. Molecular taxonomy of ...

EE - Mikrobiologie, virologie

  • 1999 - 2002
  • 3 625 tis. Kč
  • 1 250 tis. Kč
  • MŠMT
Project

Production of ergot alkaloid during the interaction of rye plant (Secale cereale) with fungus Claviceps purpurea (GAP501/12/0597)

. Infection of flowers initiates fungal sexual life cycle and synthesis of ergot alkaloids. Ergot alkaloids are used for preparation of various kind of therapeutics or change spectra of produced alkaloids ...

EI - Biotechnologie a bionika

  • 2012 - 2015
  • 7 140 tis. Kč
  • 6 840 tis. Kč
  • GA ČR
Project

Polymorphism of peptide ergot alkaloids (GA203/00/D095)

The presented grant project is focused on relationship between structural and physical properties of various crystal forms of ergot alkaloids. Suitable conditions (influence of the temperature and solvent used) for various polymorph...

CE - Biochemie

  • 2000 - 2003
  • 1 282 tis. Kč
  • 585 tis. Kč
  • GA ČR
Project

Modification of D-ring of ergot alkaloids and preparation of their oligomers (IAA4020901)

The project deals with modification of the D-ring of ergot alkaloids, namely, introduction of additional double bond(s) using Polonovski reaction and/or Potier reaction of rgot alkaloids will be prepared using appropriate s...

CC - Organická chemie

  • 1999 - 2002
  • 2 403 tis. Kč
  • 1 688 tis. Kč
  • AV ČR
Project

Biotransformation of ergot alkaloids by perosidases of plant and microbial origin (IAA455409)

9J - 9

  • 1994 - 1996
  • 657 tis. Kč
  • 996 tis. Kč
  • AV ČR
Project

X-Ray Structure Analysis and NMR of Natural and Semisynthetic Ergot Alkaloids. (GA203/94/0135)

9J - 9

  • 1994 - 1996
  • 428 tis. Kč
  • 557 tis. Kč
  • GA ČR
Project

Ergot Alkaloids as Neuroimmunomodulators of Effector-Target Cell Interaction in Antitumor Immunity (GA310/94/1542)

9H - 9

  • 1994 - 1996
  • 820 tis. Kč
  • 1 220 tis. Kč
  • GA ČR
Project

Biotransformation of natural substances (GA203/96/1267)

The aim of the project is to prepare glycosides of ergot alkaloids (galactosides, glucosides, mannosides, lactosides, glucoronides, and some N-acetylneuraminic acid derivatives of ergot alkaloid for spectral charac...

CE - Biochemie

  • 1996 - 1998
  • 2 068 tis. Kč
  • 1 358 tis. Kč
  • GA ČR
Project

Natural pseurotin alkaloids as significant immunotoxic contaminants (GA17-18858S)

characterized in number of other mycotoxins such as ergot-like alkaloids that include by pseurtoin alkaloids is not routinely screened. Thus the objective is to clarify effect of natural alkaloids structurally rel...

DN - Vliv životního prostředí na zdraví

  • 2017 - 2021
  • 4 479 tis. Kč
  • 4 479 tis. Kč
  • GA ČR
  • 1 - 10 out of 53