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Functions and interactions of the proteinkinase StkP substrates involved in cell division of Streptococcus pneumoniae (GA19-03269S)
remain poorly characterized. Our prior studies have demonstrated that eukaryotic-like Ser/Thr proteinkinase StkP of S. pneumoniae is plays an important role......
Microbiology
- 2019 - 2022 •
- 5 953 tis. Kč •
- 5 953 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2019 - 30. 6. 2022
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Analysis of substrates of Ser/Thr protein kinase StkP in Streptococcus pneumoniae and impact of phosphorylation on their function (GP204/07/P082)
systems anda single eukaryotic-type serine/threonin protein kinase StkP. Gene...
EE - Mikrobiologie, virologie
- 2007 - 2009 •
- 1 452 tis. Kč •
- 1 452 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2007 - 31. 12. 2009
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Bacterial signalling systems and regulation of the cell wall biosynthesis (IAA600200801)
Signal transduction pathways in both prokaryotes and eukaryotes utilize protein phosphorylation as a key regulatory mechanism. In bacteria, the two-component signal transduction system is predominant. Recent studies have proven that euka...
EE - Mikrobiologie, virologie
- 2008 - 2012 •
- 3 081 tis. Kč •
- 3 081 tis. Kč •
- AV ČR
Řešení projektu: 1. 1. 2008 - 31. 12. 2012
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Akademie věd České republiky
Eukaryotic-type regulatory proteins in streptomycetes Roles of WD-40 repeat proteins and protein Ser/Thr kinases (GP204/02/D120)
WD-40 repetitive proteins and protein Ser/Thr kinases represent crucial components of eukaryotic regulatory circuits, though their occurrence in prokaryotes an extra protein Ser/Thr kinase catalytic domain...
EB - Genetika a molekulární biologie
- 2002 - 2005 •
- 696 tis. Kč •
- 696 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2002 - 1. 1. 2005
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Relationship between the virulence of pathogenic bacteria and the presence of eukaryotic-type Ser/Thr protein kinases (GA204/08/0783)
Signal transduction pathways in both prokaryotes and eukaryotes utilize protein phosphorylation as a key regulatory mechanism. In bacteria, the two-component signal transduction system is predominant. Recent studies have proven that euka...
EB - Genetika a molekulární biologie
- 2008 - 2010 •
- 3 834 tis. Kč •
- 3 834 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2008 - 31. 12. 2010
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Relationship between activity of protein Ser/Thr kinases and inter- and intracellular signalling in differentiating and pathogenical bacterial species (GA204/02/1423)
in eukaryotes. To date, protein Ser/Thr kinases have been shown to be involved in three were unidentified. In the previous years we have characterized three protein Ser/Thr kinases from Streptomyces grana...
EB - Genetika a molekulární biologie
- 2002 - 2004 •
- 5 046 tis. Kč •
- 3 795 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2002 - 1. 1. 2004
Uznané náklady
Podpora ze státního rozpočtu (75%)
Poskytovatel: Grantová agentura České republiky
The role of Ser/Thr protein kinase StkP in regulation of cell division in Streptococcus penumoniae (GAP302/12/0256)
The human pathogen Streptococcus pneumoniae is an excellent model to study eukaryotic-like protein kinases in bacteria since its genome only encodes for a single Ser/Thr protein kinase StkP. Prior studies demonstrated that ...
EE - Mikrobiologie, virologie
- 2012 - 2016 •
- 7 895 tis. Kč •
- 7 895 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2012 - 31. 12. 2016
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Occurence of WD repeat proteins in prokaryotic cells and their possible role in a new type of regulation of gene expression in prokaryotes (GA204/96/1262)
conserved domains of consensus sequence of Ser/Thr protein kinases indicating been found to be regulatory proteins in eukaryotes. None is an enzyme. The WD were thought to be confined only to eukaryotes. We have r...
EE - Mikrobiologie, virologie
- 1996 - 1998 •
- 2 038 tis. Kč •
- 1 624 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1996 - 1. 1. 1998
Uznané náklady
Podpora ze státního rozpočtu (80%)
Poskytovatel: Grantová agentura České republiky
Eukaryotic-like protein kinases in Streptomyces and their function during differentiation and development (GA204/99/1534)
the previuos work on the subject we have characteized threee protein Ser/Thr kinases fromStreptomycetes are characterized by their complex life cycle and multicellular differentiation. This process undoubtedly requires various leve...
EB - Genetika a molekulární biologie
- 1999 - 2001 •
- 3 455 tis. Kč •
- 2 829 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1999 - 1. 1. 2001
Uznané náklady
Podpora ze státního rozpočtu (82%)
Poskytovatel: Grantová agentura České republiky
Eukaryotic-like protein kinases in streptomyces and their function during differentiation and development (GA204/96/1263)
for protein Ser/Thr kinases in S. granaticolor and two of them were cloned by eukaryotic-like protein kinases in the regulation of secondary metabolism in Streptomyces......
CE - Biochemie
- 1996 - 1998 •
- 1 527 tis. Kč •
- 1 190 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 1996 - 1. 1. 1998
Uznané náklady
Podpora ze státního rozpočtu (78%)
Poskytovatel: Grantová agentura České republiky
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