All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”
EN
ČeštinaEnglish

Filters

34 (0,074s) •

Project

NSF-GACR An Optical Biosensing Platform for Simultaneous Detection and Quantification of Exosomes and Exosomal Cargo Biomarkers (GF23-09170L)

Circulating exosomes have emerged as promising biomarkers for a variety of diseases. Exosomes offer two types of features that may be targeted: membrane proteins expressed at the exosome surface and cargo molecules (most of...

Optics (including laser optics and quantum optics)

  • 2023 - 2026
    • •
  • 7 554 tis. Kč
    • •
  • 7 263 tis. Kč
    • •
  • GA ČR
Project

Subcellular Biogenesis and Trafficking of Exosomes in the Context of Alzheimer´s Disease with a Specific Focus on SORL1 (GA25-16481S)

Exosomes are extracellular vesicles that play a critical role. Although implicated in Alzheimer’s disease (AD), little is known about the exosome's biogenesis in response to neuropathological conditions. We will investigate the ...

Neurosciences (including psychophysiology)

  • 2025 - 2027
    • •
  • 12 670 tis. Kč
    • •
  • 10 735 tis. Kč
    • •
  • GA ČR
Project

Molecular and functional characterization of colorectal cancer derived-exosomes and exosomal long non-coding RNAs (GA20-18889S)

Exosomes play a critical role in cell-to-cell communication locally in circulating exosomes in blood, exosomal lncRNAs can potentially serve as biomarkers but also targets for novel therapeutic approaches. During the study,...

Cell biology

  • 2020 - 2022
    • •
  • 9 311 tis. Kč
    • •
  • 9 311 tis. Kč
    • •
  • GA ČR
Project

The proteome of extracellular vesicles – the unexplored area of intercellular communication in the tumor microenvironment of head and neck cancer (NU22-03-00202)

resistance by secreting factors contained in exosomes. Exosomes are released from CAFs of cancer cells. Exosomal proteins are promising non-invasive biomarkers for many types of cancer as exosomes with tumour-spec...

Otorhinolaryngology

  • 2022 - 2025
    • •
  • 10 468 tis. Kč
    • •
  • 10 468 tis. Kč
    • •
  • MZ
Project

Exosomal RNA produced by cancer-associated fibroblasts as a relevant marker in head and neck cancer prognosis (NU20J-08-00018)

in exosomes. Exosomes released from CAFs in the tumour microenvironment may increase of RNA within exosomes has been proven. We want to investigate the RNA cargo within CAFs-derived exosomes by using Next-Gen Sequ...

Oncology

  • 2020 - 2023
    • •
  • 12 657 tis. Kč
    • •
  • 12 657 tis. Kč
    • •
  • MZ
Project

Galectin-positive glioblastoma exosomes new biomarkers and targets for glycoanotherapeutics (NU23-08-00307)

fundamentally affects the course of the disease. Extracellular vesicles/ exosomes play and anti-tumor immune response. The composition of exosomes can reflects pathological by exosomes and the associated modulation of tumo...

Oncology

  • 2023 - 2026
    • •
  • 15 509 tis. Kč
    • •
  • 15 509 tis. Kč
    • •
  • MZ
Project

Modulation of exosomal cargo by T. vaginalis endosymbionts (GC19-18773J)

, production of various surface and secreted factors, and production of exosomes of exosomes (proteome – Prague, RNA – Taipei group) derived from TVV and M. hominis the exosomal cargo. We will also test how exosomes

Microbiology

  • 2019 - 2022
    • •
  • 5 111 tis. Kč
    • •
  • 5 111 tis. Kč
    • •
  • GA ČR
Project

Role of exosomes in information transfer between cancer-associated fibroblasts and cancer cell, with emphasis on malignant melanoma (GA19-05048S)

-associated fibroblasts. Exosomes are known as important factor of cancer milieu but especially the data about the role of exosomes in cancer-associared fibroblast cancer......

Oncology

  • 2019 - 2021
    • •
  • 12 364 tis. Kč
    • •
  • 11 878 tis. Kč
    • •
  • GA ČR
Project

Treatment of spinal cord injury via targeted inhibition of the inflammasome with gene therapy stimulation of motor pathway axon regeneration (LUAUS25141)

1. Surface modification and content enrichment of exosomes derived from neural and inhibition of inflammatory signaling. 2. Validation of modified exosomes in a rat spinal cord injury model 3. Combination of modified exosomes

Neurosciences (including psychophysiology)

  • 2025 - 2028
    • •
  • 8 502 tis. Kč
    • •
  • 8 502 tis. Kč
    • •
  • MŠMT
Project

Human urinary exosomes - the source of new biomarkers for the diagnosis and follow-up of kidney diseases (NV15-31662A)

The project will study new diagnostic and predictive biomarkers in urinary exosomes in patients with immune-based kidney diseases (lupus nephrititis and ANCA-associated vasculitis) and IgA nephropathy, Urinary exosomes contain prote...

FE - Ostatní obory vnitřního lékařství

  • 2015 - 2019
    • •
  • 7 500 tis. Kč
    • •
  • 7 441 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 34