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1 561 (0,078s)

Project

Significance of mitochondrial energetics for the phenotype of adipose cell in vitro study (IAA5011710)

Our previous studies indicated new possibilities for affecting the body fat mediates thermogenesis in brown fat) decreased body fat content, changed regional fat gene transfer into white fat

EB - Genetika a molekulární biologie

  • 1997 - 2001
  • 6 029 tis. Kč
  • 2 369 tis. Kč
  • AV ČR
Project

Environmental and hereditary factors in the pathogenesis of obesity and its complications (OC B17.40)

will be examined with regard to body composition, fat distribution, mean daily energyPositive energy balance due to a high fat consumption and sedentary life style yields an increasing prevalence of obesity. Susceptibility...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2004
  • 2 020 tis. Kč
  • 1 350 tis. Kč
  • MŠMT
Project

Pathogenesis and treatment of obesity - connection with body fat distribution in obese women. Effect of change in composition of dietary fat on weight loss and mitochondrial and lipid metabolism (NB7031)

composition in serum and adipose tissue lipids is changed in obesity. Relation of body fat in dietary fat composition will be examined. Higher content of n-3 PUFA in diet decreases......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2004
  • 3 677 tis. Kč
  • 3 511 tis. Kč
  • MZ
Project

New mechanism for the control of gene expression by fatty acids in adipocytes (KJB5011410)

tissuehas a great impact on the control of body fat. Our previous studies suggested adiposity than saturated fats. Recently, research is focused on identifying mechanisms on gene expression in white fat is mediate...

EB - Genetika a molekulární biologie

  • 2004 - 2006
  • 1 239 tis. Kč
  • 999 tis. Kč
  • AV ČR
Project

Regulation of intravascular triglyceride catabolism by acute hyperinsulinemia and hyperglycemia. (NB6368)

Effect of acute hyperinsulinemia and/or hyperglycemia on total lipoprotein lipase activity in the body determined in vivo using intravenous fat tolerance test will be analyzed.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
  • 2 216 tis. Kč
  • 2 187 tis. Kč
  • MZ
Project

Endocrine regulation of circadian clock genes in relation to aging in an insect model (GAP502/10/1612)

will be compared between two peripheral tissues, the fat body and the gut. These tissues show are associated with changes in the expression levels of two circadian clock genes in the fat body. These results sugges...

ED - Fyziologie

  • 2010 - 2014
  • 6 038 tis. Kč
  • 6 038 tis. Kč
  • GA ČR
Project

Body fat distribution in obese subjects and metabolic syndrome, pathogenesis, possibilities of change by obesity treatment. Single gene mutation assessment in grossly obese patients. (NR7782)

Goal of the project is to clarify relationships of the markers of inflammation and thrombosis with adipose tissue distribution after the short term in-patient weight reducing regimen and after a long-term weight loss. Next goal is to identify the eff...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2007
  • 5 876 tis. Kč
  • 5 822 tis. Kč
  • MZ
Project

Role of mitochondria in control of adiposity and regional fat distribution (GA311/96/0681)

not only the degreeof obesity but also on the site of the body where adipose tissue and regional fat distribution may be influenced by the efficiency of energy conversion is stimulated by a high-fat diet. Continuation of t...

ED - Fyziologie

  • 1996 - 1998
  • 2 701 tis. Kč
  • 1 718 tis. Kč
  • GA ČR
Project

Reduced accumulation of fat due to omega-3 polyunsaturated fatty acid and leptin involvement of mitochondrial and lipid metabolism in adipocytes (GA303/02/1220)

It is becoming evident that accumulation of body fat depends in large on the metabolic properties of adipose tissue itself. Many genes that predispose to obesity that ectopicexpression of mitochondrial uncoupling protein 1 (UCP1) in...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2002 - 2004
  • 4 640 tis. Kč
  • 2 939 tis. Kč
  • GA ČR
Project

Leptin in patiens with nephrotic syndrome (NB5989)

The aim of the study is to evaluate plasma leptin concentrations in 30 patiens with nephrotic syndrome and changes of these concentrations due to steroid treatment,protein metabolism,glucose tolerance and body fat content.......

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
  • 1 142 tis. Kč
  • 977 tis. Kč
  • MZ
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