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Inborn skeletal disorders caused by mutations in fibroblast growth factor receptors/FGFR/ (NM25)
Mutations of the genes coding for fibroblast growth factor receptors(FGFR)and their phenotypic expression will be studied in patients with selected inborn skeletal disorders in order to improve diagnostics and classificatio...
EB - Genetika a molekulární biologie
- 1998 - 2000 •
- 2 185 tis. Kč •
- 2 185 tis. Kč •
- MZ
Řešení projektu: 1. 1. 1998 - 1. 1. 2000
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Production of stable fibroblast growth factors for research, therapeutic and cosmetic applications (TH02010219)
The aim of the project is to remove low stability of fibroblast growth factors (FGFs) that prevents their practical use. FGFs are proteins that promote cell proliferation and differentiation in the human body and, thus, fac...
EI - Biotechnologie a bionika
- 2017 - 2020 •
- 20 364 tis. Kč •
- 12 186 tis. Kč •
- TA ČR
Řešení projektu: 1. 1. 2017 - 31. 12. 2020
Uznané náklady
Podpora ze státního rozpočtu (60%)
Poskytovatel: Technologická agentura ČR
Fibroblast growth factor signaling pathways in human embryonic stem cells (GA305/05/0434)
exists regarding growth factor signaling in this particular cell type. It has been demonstrated that hES cells require exogenous basic fibroblast growth factor (FGF-2 forundifferentiated growth. ...
ED - Fyziologie
- 2005 - 2007 •
- 4 602 tis. Kč •
- 4 602 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2005 - 31. 12. 2007
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Structure-function relationship in fibroblast growth factors signaling (GF21-26400K)
Fibroblast growth factors (FGFs) interact with four types of cell surface receptors (FGFRs) to deliver signals critical for development and functioning of mammalian organs. FGFs trigger proliferative, migrational, anti-apop...
Cell biology
- 2021 - 2023 •
- 10 068 tis. Kč •
- 10 068 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2021 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Exploiting the regenerative potential of the stable fibroblast growth factor 2 in cosmeceutics (EG20_321/0023865)
fibroblast growth factor with a positive effect on skin regeneration and repair. HoweverThe aim of the presented project is to develop a prototype of an innovative cosmetic product with a bioactive substance, which will be...
Chemical process engineering
- 2021 - 2023 •
- 6 715 tis. Kč •
- 0 tis. Kč •
- MPO
Řešení projektu: 1. 1. 2021 - 1. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (0%)
Poskytovatel: Ministerstvo průmyslu a obchodu
Role of exosomes in information transfer between cancer-associated fibroblasts and cancer cell, with emphasis on malignant melanoma (GA19-05048S)
microenvironment on growth and spreading of malignant tumors with important role of cancer-associated fibroblasts. Exosomes are known as important factor of cancer milieu but especially the data about the role of exosomes ...
Oncology
- 2019 - 2021 •
- 12 364 tis. Kč •
- 11 878 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2019 - 31. 12. 2021
Uznané náklady
Podpora ze státního rozpočtu (96%)
Poskytovatel: Grantová agentura České republiky
Precise targeting of the FGF signaling system by DNA aptamers (GF25-15902K)
The fibroblast growth factor (FGF) family comprises 18 morphogens, growth factors and metabolic hormones that signal via four transmembrane receptors (FGFR1-4). Experimental studies confirm more than 62 FG...
Biochemistry and molecular biology
- 2025 - 2027 •
- 13 356 tis. Kč •
- 13 356 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2025 - 31. 12. 2027
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
Tumor microenvironment of head and neck carcinoma Prognostic significance of extracellular matrix produced by tumor-associated fibroblasts (NV15-28933A)
, in addition to cytokines/chemokines/growth factors, the main product of cancer-associated fibroblasts as important representatives of cancer stromal cells. Our previous study of local fibroblasts on cancer-associ...
FF - ORL, oftalmologie, stomatologie
- 2015 - 2018 •
- 11 720 tis. Kč •
- 11 720 tis. Kč •
- MZ
Řešení projektu: 1. 5. 2015 - 31. 12. 2018
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Ministerstvo zdravotnictví
Integrating Sprouty function with FGF and primary cilia during development (GA21-04178S)
Sprouty proteins provide a control mechanism for appropriate receptor tyrosine kinase signaling, including the fibroblast growth factor (FGF) signaling pathway. Knockout of Sproutys cause a range of developmental abnormali...
Developmental biology
- 2021 - 2023 •
- 11 452 tis. Kč •
- 11 452 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2021 - 31. 12. 2023
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
FGF signalling in mammary fibroblasts and its role in mammary gland development and cancer (GJ16-20031Y)
. Fibroblast growth factor (FGF) signalling mediates epithelial-stromal interactions during to examine how FGF signalling in mammary stromal fibroblasts regulates mammary gland that regulation of mammary fibrob...
EB - Genetika a molekulární biologie
- 2016 - 2020 •
- 5 121 tis. Kč •
- 5 121 tis. Kč •
- GA ČR
Řešení projektu: 1. 1. 2016 - 22. 7. 2020
Uznané náklady
Podpora ze státního rozpočtu (100%)
Poskytovatel: Grantová agentura České republiky
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