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2 701 (0,121s)

Project

The role of free fatty acids in the pathogenesis of insulin resistance and its complications. (NB6367)

for nutritional and pharmacological interventions decreasing free fatty acids release from hypertriglyceridemic rat line, the role of long-term increased circulating level of free fatty acids on ...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2000 - 2002
  • 3 474 tis. Kč
  • 3 474 tis. Kč
  • MZ
Project

Effect of insulin and free fatty acids on the production of selected cytokines in adipose tissue in type 2 diabetic patients and healthy subjects. (NB7517)

The aim of the study is to test the effect of in vivo induced hyperinsulinemia/ or elevation of free fatty acids on expression of adiponectin, resistin, leptin, TNFalfa and SREBP-1 in subcutaneous adipose tissue in patients...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2003 - 2005
  • 4 929 tis. Kč
  • 4 694 tis. Kč
  • MZ
Project

Fatty acids with antimicrobial activity as a nutraceutical alternative for in-feed antibiotics in farm animals nutrition (QF3134)

This project aims at using medium-chain fatty acids as the alternative for feed antibiotics in farm animals nutrition. These fatty acids and their derivatives have and calves. In most active fatty acid...

GH - Výživa hospodářských zvířat

  • 2003 - 2007
  • 6 570 tis. Kč
  • 6 570 tis. Kč
  • MZe
Project

Effect of medium-chain fatty acids on performance, mortality and digestibility of nutrients in young rabbits (GA523/02/0460)

project is aimed at testing medium-chain fatty acids, primarily free or bound caprylic and capric acid, as supplements of rabbit post-weaning diets. These acids are natural bacteria to fatty ...

GH - Výživa hospodářských zvířat

  • 2002 - 2004
  • 1 743 tis. Kč
  • 1 263 tis. Kč
  • GA ČR
Project

Fatty acid cycling by phosphate carrier and uncoupling protein 2. (ME 389)

Kinetic studies of fatty acid cycling and fatty acid interaction inhibitors. Location of the fatty acid binding site in their sequences after photoaffinity labeling with radiolabeled azido-fat...

EB - Genetika a molekulární biologie

  • 2000 - 2003
  • 1 780 tis. Kč
  • 1 100 tis. Kč
  • MŠMT
Project

New electrochemical approaches for the study of modified fatty acids and their biomolecular interactions (GJ19-21237Y)

The proposed project deals with the analysis of modified fatty acids fatty acid modifications occur under oxidative conditions and thus affect mainly to develop new methods for the analysis of modified fatty

Biophysics

  • 2019 - 2022
  • 5 843 tis. Kč
  • 5 843 tis. Kč
  • GA ČR
Project

Metabolic factors involved in progression of chronic heart failure (NS10497)

Abnormalities of substrate metabolism in chronic heart failure (CHF) may contribute to the progression of contractile dysfunction. Important role may have stimulation of adipose tissue lipolysis by catecholamines and perhaps also by natriuretic pepti...

FA - Kardiovaskulární nemoci včetně kardiochirurgie

  • 2009 - 2011
  • 4 375 tis. Kč
  • 4 375 tis. Kč
  • MZ
Project

Development of environmentally friendly hydrogenation catalysts (FV40158)

The aim of the project is to develop a new chromium-free hydrogenation catalyst of comparable stability, activity as well as life expectancy to the currently used copper-chromium based catalyst.......

Chemical engineering (plants, products)

  • 2019 - 2022
  • 12 993 tis. Kč
  • 8 318 tis. Kč
  • MPO
Project

Impaired Free Fatty Acids Metabolism in Obstructive Sleep Apnea Syndrome (NV15-30155A)

hypothesize that elevated levels of free fatty acids (FFA), as detected in OSA patients...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2015 - 2018
  • 16 128 tis. Kč
  • 16 077 tis. Kč
  • MZ
Project

Role of fatty acid binding proteins in pathophysiology of insulin resistance in humans (NR7880)

To measure the expression s of fatty acid-bunding proteins in monocytes and adipose tissue in relation to metabolism of fatty acids and selected clinical and biochemical manifestations of insulin resistance in pati...

FB - Endokrinologie, diabetologie, metabolismus, výživa

  • 2004 - 2006
  • 5 882 tis. Kč
  • 5 560 tis. Kč
  • MZ
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