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97 (0,065s) •

Project

Primary progressive aphasia – clinical, MRI and structural correlations. A prospective multicenter study (NV18-04-00346)

with frontotemporal dementia, 20-30 Alzheimer’s disease patients and 20-30 patients with vascularPrimary progressive aphasias (PPA) are neurodegenerative disorders with an initial isolated language impairment progressing into d...

Clinical neurology

  • 2018 - 2022
    • •
  • 14 247 tis. Kč
    • •
  • 13 667 tis. Kč
    • •
  • MZ
Project

Investigating the effects of tau mutations on the activity of VQIVYK-targeting agents on tau seeding in neurodegenerative diseases (GC23-06301J)

Tauopathies, including Alzheimer's disease and frontotemporal dementia, are a group of neurological disorders characterised by intracellular deposits of tau aggregates. Evidence suggests that pathogenic tau develops early in patient...

Cell biology

  • 2023 - 2025
    • •
  • 7 776 tis. Kč
    • •
  • 7 776 tis. Kč
    • •
  • GA ČR
Project

Multidisciplinary approach in the diagnosis of frontotemporal lobar degenerations and tauopathies new insights into pathogenetic mechanisms (NT12094)

Genetic aspects of neurodegenerative diseases and a multidisciplinary approach are of increasing importance. In this study we will enroll patients fulfilling clinical diagnostic criteria of different forms of frontotemporal lobar degeneratio...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2015
    • •
  • 10 440 tis. Kč
    • •
  • 10 440 tis. Kč
    • •
  • MZ
Project

Telemedicine self-examination of speech and memory for rapid detection of cognitive impairments using machine learning methods (TQ01000332)

Early cognitive disorders diagnosis is becoming increasingly important due to population aging. The most common causes include Alzheimer's disease and frontotemporal dementia. These diseases are also manifested by changes in speech....

Psychology, special (including therapy for learning, speech, hearing, visual and other physical and mental disabilities);

  • 2023 - 2026
    • •
  • 12 782 tis. Kč
    • •
  • 10 206 tis. Kč
    • •
  • TA ČR
Project

Role of frontotemporal crosstalk in cognitive coordination and flexibility deficits in schizophrenia A translational study (NV17-30833A)

of frontotemporal theta coherence and synchrony will be revealed by controlling PV+ interneuron activity in freely-moving rats. The human part will test relations of frontotemporal will unequivocally show the constituents of fr...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2020
    • •
  • 12 693 tis. Kč
    • •
  • 12 693 tis. Kč
    • •
  • MZ
Project

Disruption of spatiotemporal coordination as an early marker of schizophrenia A translational study of a role of frontotemporal interaction (NU22-04-00526)

of frontotemporal disconnection and schizophrenia, which can serve as a more reliable predictor behavioral testing, and relate disrupted frontotemporal crosstalk to the dysfunctioning......

Neurosciences (including psychophysiology)

  • 2022 - 2025
    • •
  • 12 309 tis. Kč
    • •
  • 12 309 tis. Kč
    • •
  • MZ
Project

Possible influence of atherosclerosis on dementia development (NU20-09-00119)

Atherosclerosis and dementia or mild cognitive impairment may have similar risk factors. Atherosclerosis is believed to be involved in development of dementia and its major subtypes, vascular dementia and Alzheimer’s diseas...

Epidemiology

  • 2020 - 2023
    • •
  • 12 600 tis. Kč
    • •
  • 12 600 tis. Kč
    • •
  • MZ
Project

Social life of dementia cultural representations and subjective attitudes (GA21-16738S)

The project focuses on the social representations of dementia, both in media analyses how dementia is represented in Czech media and social and healthcare policy to explore how the idea of what dementia means is constructed...

Sociology

  • 2021 - 2023
    • •
  • 2 510 tis. Kč
    • •
  • 2 510 tis. Kč
    • •
  • GA ČR
Project

TACKLing the challenges of PREsymptomatic sporadic Dementia (8F2205)

To leverage large, multimodal datasets from patients representing the full spectrum of neurodegenerative dementia as well as those at risk and apply well-informed data-driven analytic approaches to identify neurodegenerative dementia

Neurosciences (including psychophysiology)

  • 2022 - 2024
    • •
  • 9 786 tis. Kč
    • •
  • 9 786 tis. Kč
    • •
  • MŠMT
Project

TACKLing the challenges of PREsymptomatic sporadic Dementia (8F22005)

To leverage large, multimodal datasets from patients representing the full spectrum of neurodegenerative dementia as well as those at risk and apply well-informed data-driven analytic approaches to identify neurodegenerative dementia

Neurosciences (including psychophysiology)

  • 2022 - 2025
    • •
  • 9 786 tis. Kč
    • •
  • 9 786 tis. Kč
    • •
  • MŠMT
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