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12 (0,069s) •

Project

Detection of the dynamic of gadolinium retention in the brain after application of MR contrast agents using alteration of T1 and T2 relaxation times. Prospective study. (NV18-04-00457)

Gadolinium retention in various organs including the brain after application of MR contrast agents is a important phenomenon. Its pathophysiology and clinical relevance have not yet been reliably evaluated. Gadolinium retention in t...

Clinical neurology

  • 2018 - 2022
    • •
  • 2 891 tis. Kč
    • •
  • 2 891 tis. Kč
    • •
  • MZ
Project

Single crystals of yttrium-iron and bismuth gadolinium-iron garnet for magneto-optical applications (IAA210438)

9N - 9

  • 1994 - 1995
    • •
  • 215 tis. Kč
    • •
  • 430 tis. Kč
    • •
  • AV ČR
Project

Combined contrast agents for molecular MR imaging (KAN201110651)

on gadolinium(III), will be tested (tuning parameters on a molecular level). Combination of simple gadolinium(III) complexes and oxidic nanoparticles as well as their conjugates......

CA - Anorganická chemie

  • 2006 - 2010
    • •
  • 38 361 tis. Kč
    • •
  • 32 126 tis. Kč
    • •
  • AV ČR
Project

Synthesis and screening of selective probes for magnetic resonance imaging (GJ17-22834Y)

Project is focused on preparation of responsive contrast agents based on gadolinium(III) chelates. These compounds can serve as molecular sensors for whole-body mapping of biomolecules with magnetic resonance imaging (MRI). New amino acid bu...

CC - Organická chemie

  • 2017 - 2021
    • •
  • 5 331 tis. Kč
    • •
  • 5 331 tis. Kč
    • •
  • GA ČR
Project

Microstructure investigation of thin metal films (MEB101102)

Application of positron spectroscopies to structural characterization and behaviour of defects in selected epitaxial and polycrystalline metallic films prepared under different conditions and deposited on appropriate substrates is the main goal of th...

BM - Fyzika pevných látek a magnetismus

  • 2011 - 2012
    • •
  • 145 tis. Kč
    • •
  • 145 tis. Kč
    • •
  • MŠMT
Project

Advanced magnetic resonance imaging of pediatric brain tumors /PediTuMRI/ (NU23-08-00460)

on the injection of a gadolinium-based contrast agent to produce post-contrast images, which is subject to growing concerns about gadolinium accumulation in the body. Second......

Other clinical medicine subjects

  • 2023 - 2026
    • •
  • 14 598 tis. Kč
    • •
  • 14 598 tis. Kč
    • •
  • MZ
Project

Novel classes of contrast agents for magnetic resonance imaging (GAP207/11/1437)

Magnetic resonance imaging (MRI) is one of the most important medicinal diagnostic methods. For a better resolution of the images, the substances called contrast agents (CAs) are often administered. They are mostly Gd3+-complexes, which contain one c...

CA - Anorganická chemie

  • 2011 - 2015
    • •
  • 11 714 tis. Kč
    • •
  • 11 714 tis. Kč
    • •
  • GA ČR
Project

Nanoliposomal systems for rapid diagnosis of thrombi by MRI (NV16-30299A)

are based on nanoliposomes labelled with gadolinium complexes for rapid and sensitive...

FH - Neurologie, neurochirurgie, neurovědy

  • 2016 - 2020
    • •
  • 11 908 tis. Kč
    • •
  • 11 132 tis. Kč
    • •
  • MZ
Project

Novel cancer diagnostics based on glycogen as body´s own nanosized carrier (NV15-25781A)

The ultimate goal of this project is to improve care about the patients with cancer by developing new noninvasive diagnostic and possibly also theranostic imaging tools based on polysaccharide materials. They may serve as customizable toolbox-like ca...

FR - Farmakologie a lékárnická chemie

  • 2015 - 2018
    • •
  • 11 525 tis. Kč
    • •
  • 10 601 tis. Kč
    • •
  • MZ
Project

Novel Metal-Free Contrast Agents for 1H Magnetic Resonance and Optical Imaging (NW24-08-00144)

This research proposal aims to design and evaluate novel, metal-free contrast agents for Magnetic Resonance Imaging (MRI). The objective is to overcome the limitations of conventional metal-based contrast agents, such as gadolinium chelates ...

Medicinal chemistry

  • 2024 - 2027
    • •
  • 13 318 tis. Kč
    • •
  • 13 318 tis. Kč
    • •
  • MZ
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