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4 995 (0,165s) •

Project

Gene expression profiling-based prediction of treatment response for patient with locally advanced rectal cancer treated by chemotherapy and radiotherapy (NR9076)

and the aim is to identify gene expression profile of these tumors (in vivo). It is clearly demonstrated that biological correlates of gene expression are identifiable to identify gene expres...

FD - Onkologie a hematologie

  • 2006 - 2010
    • •
  • 10 983 tis. Kč
    • •
  • 10 373 tis. Kč
    • •
  • MZ
Project

Gene expression profiling during mouse spermatogenesis Implications for meiotic sex chromosome inactivation and gene retroduplication (GA301/07/1383)

) will be dissected by genome wide expression profiles acquired using DNA microarrays. We will determine gene expression profiles of two strains C57BL/6J and PWD/Ph for three distinct of gene retr...

EB - Genetika a molekulární biologie

  • 2007 - 2009
    • •
  • 2 472 tis. Kč
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  • 2 472 tis. Kč
    • •
  • GA ČR
Project

MitoChip microarray for mitochindrial gene expression analysis and its application for study of nuclear defects of oxidative phosphorylation (NR8069)

. Gene expression profiling represents a new method which has a potential microarray for expression profiling of all of human mitochondrial genes and gene expression profilin...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 6 198 tis. Kč
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  • 6 060 tis. Kč
    • •
  • MZ
Project

INVESTIGATION OF GENE EXPRESSION PROFILING IN PATIENTS WITH MYELODYSPLASTIC SYNDROME (NR9235)

1. Analysis of gene expression profile in MDS patients using cDNA microarray assay . Investigation of mutation status of proliferation genes and by determination of methylation status of differentiation genes

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 9 504 tis. Kč
    • •
  • 9 117 tis. Kč
    • •
  • MZ
Project

Genetic profile of biotransformation and DNA repair genes in cancer patients from the Czech Republic. (NR8563)

Evaluation of links between individual genetic background - evaluation of polymorphisms in both DNA repair and XME genes and expression levels in lymphocytes in cancer patients and healthy controls in Czech Republic. Determination o...

EB - Genetika a molekulární biologie

  • 2005 - 2009
    • •
  • 9 468 tis. Kč
    • •
  • 6 102 tis. Kč
    • •
  • MZ
Project

Integrated microRNA, mRNA expression profiling, linkage and correlation analyses for identification of genes underlying complex traits (GAP301/10/0290)

that control gene expression and could be pivotal regulators in normal physiology as well as in disease development. In the current project, we will determine miRNA expression profiles in mutliple tissues relevant...

EB - Genetika a molekulární biologie

  • 2010 - 2014
    • •
  • 6 393 tis. Kč
    • •
  • 6 393 tis. Kč
    • •
  • GA ČR
Project

Molecular signature of centrosome abnormalities and their clinical impact for patients with multiple myeloma (NT13190)

on expression profile of genes known to be involved in regulating centrosome duplication that expression of these genes can stratify MM patients into groups with divergent prognosis. Main objectives of pl...

EB - Genetika a molekulární biologie

  • 2012 - 2014
    • •
  • 8 515 tis. Kč
    • •
  • 8 515 tis. Kč
    • •
  • MZ
Project

Cyclooxygenases down-regulation and the influence on the gene expression (NR8760)

or retrovirus mediated shRNA expression, respectively. The gene expression profile will be determined by DNA microarrays comparing the gene expression with parental cell-lineThe aim of this study...

EB - Genetika a molekulární biologie

  • 2006 - 2009
    • •
  • 6 423 tis. Kč
    • •
  • 6 370 tis. Kč
    • •
  • MZ
Project

Pathogenesis of spontaneous hypertension integrated analysis of intermediary phenotypes of autonomic/sympathetic system and gene expression profiles in rat recombinant inbred strains (IAA500110604)

of RI strains is covered by more than 1000 gene markers and the strains are characterized in multiple hemodynamic and metabolic traits and in gene expression profiles traits and regulatory gene networks. ...

EB - Genetika a molekulární biologie

  • 2006 - 2009
    • •
  • 2 872 tis. Kč
    • •
  • 2 872 tis. Kč
    • •
  • AV ČR
Project

Expression-profiling of chemokine ligands and receptors in pulmonary sarcoidosis (GA310/05/2614)

patients, mRNA expression of genes, relevant for chemokine-driven migration processes, will be quantitated using real time-PCR methodology, and compared to gene expression in cellsfrom control, healthy subjects. S...

EC - Imunologie

  • 2005 - 2007
    • •
  • 3 297 tis. Kč
    • •
  • 3 297 tis. Kč
    • •
  • GA ČR
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