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3 502 (0,079s) •

Project

Screening of mutations in the PKD2 gene from families with autosomal dominant polycystic kidney disease. (NE5996)

Analysis of mutations in PKD2 gene in selected families with ADPKD by screening methods (SSCP,HA,DGGE) and following sequenation of positive fragments. Analysis of mutations in PKD2 gene is the only temporary available meth...

FE - Ostatní obory vnitřního lékařství

  • 2000 - 2002
    • •
  • 3 422 tis. Kč
    • •
  • 3 420 tis. Kč
    • •
  • MZ
Project

Screening of mutations in the non-duplicated region of the PKD1 gene from families with autosomal dominant polycystic kidney disease (NE7633)

Analysis of mutations in non-duplicated region of the PKD1 gene in selected families with ADPKD by screening methods (SSCP,HA,DGGE) and following sequencing of positive fragments.......

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 3 439 tis. Kč
    • •
  • 3 364 tis. Kč
    • •
  • MZ
Project

Screening of mutations in the duplicated region of the PKD1 gene from families with autosomal dominant polycystic kidney disease (NR9427)

Analysis of mutations in duplicated region of the PKD1 gene in selected families with ADPKD by LR-PCR , screening methods (SSCP,HA,DGGE) and following sequencing of positive fragments.......

EB - Genetika a molekulární biologie

  • 2007 - 2010
    • •
  • 4 789 tis. Kč
    • •
  • 4 669 tis. Kč
    • •
  • MZ
Project

Mutational analysis of BRCA1 and BRCA2 genes in hereditary forms of breast and ovarian cancer. Clinical application in the South Moravian region. (NC5561)

Molecular-genetic testing of mutations in BRCA1 and BRCA2 genes by some of the screening methods (SSCP,HA,CDCE,PTT) Sequencing analysis of PCR fragments with detected mutations by screening methods.......

FD - Onkologie a hematologie

  • 1999 - 2001
    • •
  • 3 675 tis. Kč
    • •
  • 3 675 tis. Kč
    • •
  • MZ
Project

Screening of the eucaryoitic genes activated by the presence of heavy metals in environment (GA204/95/0946)

9H - 9

  • 1995 - 1996
    • •
  • 160 tis. Kč
    • •
  • 160 tis. Kč
    • •
  • GA ČR
Project

Role of dominant susceptibility genes in breast tumorigenesis - RNA-based analyses (NR9051)

The role of missense variants in BRCA1 and BRCA2 genes will be analyzed in brest cancer tumorigenesis. BRCA1 a BRCA2 genes will be screened for rearrangements and splice variants. Mutational analysis of ATM gene wi...

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 2 936 tis. Kč
    • •
  • 2 808 tis. Kč
    • •
  • MZ
Project

Gene screening of actinomycetes producing new substances with potential therapeutic applications to modulate immune mechanisms. (IAA600660607)

in treatment of inflammation. Based on our knowledge on the function of gene essential for their biosynthesis, we have designed a method of the specific genetic screening to identify new metabolites will be selected by genetic ...

EE - Mikrobiologie, virologie

  • 2006 - 2008
    • •
  • 4 337 tis. Kč
    • •
  • 4 337 tis. Kč
    • •
  • AV ČR
Project

Study of in vivo expression of genes involved in the cytokinin degradation in the plants with agricultural significance (GP204/03/P103)

- cytokinin dehydrogenases/oxidases. Recently we have started screening of genes also know partial information of several other genes active in different developmental stages. Cytokinin dehydrogenase/oxidase is probably en...

EB - Genetika a molekulární biologie

  • 2003 - 2005
    • •
  • 1 350 tis. Kč
    • •
  • 696 tis. Kč
    • •
  • GA ČR
Project

The effect of manumycin-related compounds on innate immunity cells and their interactions (NT13012)

. For a screening of potential effect of tested compounds on pro-inflammatory cytokines screening will be used for identification of streptomycete strains producing manumycine of manumycins (length, branching, saturation) including ...

EC - Imunologie

  • 2012 - 2015
    • •
  • 7 827 tis. Kč
    • •
  • 7 827 tis. Kč
    • •
  • MZ
Project

Optimalization of newborn screening of cystic fibrosis (NS9986)

Newborn screening for cystic fibrosis (NSCF) is based on examination of concentration of imunoreactive trypsinogen (IRT) and DNA analysis of CFTR gene in blood spots on screening cards. DNA analysis could be replaced with p...

FG - Pediatrie

  • 2008 - 2011
    • •
  • 10 604 tis. Kč
    • •
  • 10 597 tis. Kč
    • •
  • MZ
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