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3 504 (0,107s) •

Project

Spatiotemporal transcriptome and proteome analysis of α-Synuclein pathology in Parkinson’s disease Identification of cell type-specific vulnerability and tolerance mechanisms (9F24003)

and integration with clinical, neuropathological, and genomic (e.g., GBA and HLA-R genetic...

Other medical science

  • 2024 - 2027
    • •
  • 6 633 tis. Kč
    • •
  • 6 633 tis. Kč
    • •
  • MŠMT
Project

Environmental constraints on the evolution of plant genome architecture – regional and community scales perspectives (GA14-30313S)

In the project we aim to produce simple genomic data (monoploid genome size, genomic GC content and ploidy level) for complete vascular plant flora of the Czech effect of species interactions and of different spatial sc...

EF - Botanika

  • 2014 - 2018
    • •
  • 7 889 tis. Kč
    • •
  • 7 889 tis. Kč
    • •
  • GA ČR
Project

Genomic substrates of chromosome rearrangements and dysploidy during plant evolutionary diversification (GF21-07748L)

small- vs. large-scale restructuring events affecting coding vs. non-coding genomeGenome divergence is usually associated with restructuring events, such as gene dysploidy). Mechanisms, molecular features and evolutionary ...

Plant sciences, botany

  • 2021 - 2023
    • •
  • 12 160 tis. Kč
    • •
  • 11 821 tis. Kč
    • •
  • GA ČR
Project

Ecological genomic approaches to uncovering the adaptive significance of seed dormancy in legumes. (GA16-21053S)

Current advances in genomics allow genome-wide studies, and similarly information systems provide information at continental scale. The proposal aims to provide insight into evolutionary and genomic consequences of...

EF - Botanika

  • 2016 - 2020
    • •
  • 5 661 tis. Kč
    • •
  • 5 661 tis. Kč
    • •
  • GA ČR
Project

Large scale organization of chromatin (GA304/01/0729)

The cell nucleus represents the place where genomic DNA is accommodated. As the linear DNA length of a mammalian genome may be several meters and the diameter of the nucleus is only 10-15 um several levels of chromatin condensation ...

EA - Morfologické obory a cytologie

  • 2001 - 2003
    • •
  • 5 749 tis. Kč
    • •
  • 4 671 tis. Kč
    • •
  • GA ČR
Project

Pan-European Lake Sampling - Microbial Eco-genomics (PELAGICS) (GX20-12496X)

isolation we aim for stable cultivation and whole-genome sequencing of 500 prokaryotes and 50 unicellular eukaryotes. Moreover, terabyte scale deep-metagenomic sequencing (ca. 18 TB) will allow recovery of thousands of metagenome-a...

Microbiology

  • 2020 - 2025
    • •
  • 49 748 tis. Kč
    • •
  • 49 748 tis. Kč
    • •
  • GA ČR
Project

Center of Integrated Genomics (LN00A079)

of genomics.Large-scale DNA sequencing (of eg. bacterial genomes) is well establishedand basicThe proposed Center of Genomics is created to enable collaboration of top laboratories in various aspects of genomics w...

EB - Genetika a molekulární biologie

  • 2000 - 2004
    • •
  • 132 608 tis. Kč
    • •
  • 106 170 tis. Kč
    • •
  • MŠMT
Project

European large-scale functional genomics in the rat for translational research (7E10067)

Genetic studies in model organisms and humans, including human genome-wide association studies, have pinpointed genomic regions that contribute susceptibility project in which we will use state-of-the-art and emerging large-scal...

EB - Genetika a molekulární biologie

  • 2010 - 2014
    • •
  • 2 707 tis. Kč
    • •
  • 2 707 tis. Kč
    • •
  • MŠMT
Project

High resolution genomic analysis of introgression across a species barrier (GA15-13265S)

and Neanderthals have provoked strong interest in fine scale patterns of introgression within genomes. Recently we have constructed a survey of precisely these fine scale patterns in the only mammalian admixture system wit...

EG - Zoologie

  • 2015 - 2019
    • •
  • 9 999 tis. Kč
    • •
  • 9 999 tis. Kč
    • •
  • GA ČR
Project

Post-polyploid genome evolution in Microlepidieae (Brassicaceae) (GJ20-03419Y)

) elucidate dynamics of transposable elements and small-scale genomic variations, and (v shaped genome evolution, speciation and cladogenesis in plants. Yet, little is known into the subgenome evolution in MICR and evolutio...

Plant sciences, botany

  • 2020 - 2022
    • •
  • 6 567 tis. Kč
    • •
  • 6 567 tis. Kč
    • •
  • GA ČR
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