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1 539 (0,1s) •

Project

The study on causes of early embryo mortality by comparative genome hybridization (QH81068)

Although the chromosome aberrations are a considerable factor influencing applications. The aim of this project is to describe numerical chromosomal aberrations of the concern. We will use the whole genome amplification and...

EB - Genetika a molekulární biologie

  • 2008 - 2010
    • •
  • 3 024 tis. Kč
    • •
  • 2 871 tis. Kč
    • •
  • MZe
Project

MOLECULAR CYTOGENETIC ANALYSIS OF BRAIN TUMOUR CELLS AND ITS CONTRIBUTION TO DIAGNOSIS AND TREATMENT. (1A8237)

Molecular cytogenetic study of large cohort of patients with brain tumours. Identification of the most frequent chromosomal changes and evaluation of significance of single and cumulative cytogenetic aberrations for course and prognosis of t...

EB - Genetika a molekulární biologie

  • 2004 - 2006
    • •
  • 2 206 tis. Kč
    • •
  • 1 903 tis. Kč
    • •
  • MZ
Project

Comparative genomic hybridization (CGH) - new method of the detection of chromosomal aberrations in chronic B-cell leukemias (GA312/97/0125)

Comparative genomic hybridization is a new method in which complete or partial genomes with unknown rearrangement can be analysed and only DNA is required for the procedure. Differentially labeled tumor and genomic control ...

FD - Onkologie a hematologie

  • 1997 - 1999
    • •
  • 4 101 tis. Kč
    • •
  • 4 101 tis. Kč
    • •
  • GA ČR
Project

Anaerobic ciliates as a model group to study alternative nuclear genetic codes (GA25-17400S)

spot for the emergence of various nuclear genetic code aberrations. All these aberrations involve reassignments of stop codons. The most frequent is the reassignment for studying evolutionary changes from standard genetic code to i...

Biology (theoretical, mathematical, thermal, cryobiology, biological rhythm), Evolutionary biology

  • 2025 - 2027
    • •
  • 11 532 tis. Kč
    • •
  • 11 532 tis. Kč
    • •
  • GA ČR
Project

Study of the role of genetic and chromosomal aberrations as part of malignant transformation of MGUS and in the course of multiple myeloma – use of the findings for diagnosis and stratification (NT14400)

for a study of genetic and chromosomal changes in the cancer genome of individuals and aberrations in progression/relapse and treatment failure: a) cytogenetic study of the genome of patients using FISH and high-resolution...

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 7 993 tis. Kč
    • •
  • 7 830 tis. Kč
    • •
  • MZ
Project

Genomic instability of leukemic cells at chromosomal level (GA301/04/0407)

Genomic instability is in the most tumors manifested by chromosomal), multicolor banding (mBAND) and comparative genomic hybridization (CHG) was found complex chromosomal aberrations in bone marrow cells of adult patients a...

FD - Onkologie a hematologie

  • 2004 - 2006
    • •
  • 2 710 tis. Kč
    • •
  • 2 710 tis. Kč
    • •
  • GA ČR
Project

High throughput detection of genetic alterations in chronic lymphocytic leukemia using array comparative genomic hybridization (NR9484)

I. The utilization of array comparative genomic hybridization (array-CGH) for determination of DNA copy number changes in patients with chronic B lymphocytic leukemia (B) and FISHto map new cryptic aberrations. III. By using molecul...

FD - Onkologie a hematologie

  • 2007 - 2009
    • •
  • 8 360 tis. Kč
    • •
  • 7 861 tis. Kč
    • •
  • MZ
Project

The implication of genomic changes in pathogenesis of low grade brain gliomas and their correlation with H-MRSI spectroscopy and histological analysis (NT13212)

Prospective a retrospective molecular cytogenetic analysis of the tumor cell genome in patients with low-grade gliomas. Detection of specific chromosomal aberrations using I-FISH and MLPA, identification of recurrent changes in DNA ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2012 - 2015
    • •
  • 5 647 tis. Kč
    • •
  • 5 647 tis. Kč
    • •
  • MZ
Project

Methodical centre for the application of molecular methods io cytogenesis (GA523/99/M030)

structural aberrations using the multicolour FISH. (2) Construction of region-specific genomic DNA libraries to obtain chromosome-specific probes for the studies of genomic regions containing genes relevant to performance ...

GI - Šlechtění a plemenářství hospodářských zvířat

  • 1999 - 1999
    • •
  • 5 657 tis. Kč
    • •
  • 5 657 tis. Kč
    • •
  • GA ČR
Project

The idtroduction of comparative genomic hybridization in chidhood ALL to detection and study of clinical importance of genetic changes. (IZ4026)

The introducing of the method of CGH,used in the detect. of chromosom. aberrations in childhood ALL.The differentially labeled tumor and control DNA are cohybridized to normal chromosomes under suppress. conditions and detected using deffere...

FG - Pediatrie

  • 1997 - 1999
    • •
  • 1 904 tis. Kč
    • •
  • 1 904 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 1 539