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6 013 (0,254s) •

Project

Molecular mechanisms of regulation and function of autophagy in adaptation and longevity of U cell subpopulation of differentiated yeast colonies (LD15129)

and regulation of autophagy in cells of differentiated yeast colonies, namely i) new findings about the importance of active autophagy in rebuilding metabolism of subpopulation of colonial U cells and in vitality ...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 1 593 tis. Kč
    • •
  • 1 593 tis. Kč
    • •
  • MŠMT
Project

3D yeast colony genomics A model for cancer progression and development of drug resistance in biofilms (7F14083)

molecular mechanisms involved in development of yeast cells within differentiated colony) Quantitative analysis of transcriptomes of different types of differentiated cells of yeast colonies by RNA Seq; ii) identi...

EB - Genetika a molekulární biologie

  • 2014 - 2017
    • •
  • 25 076 tis. Kč
    • •
  • 25 076 tis. Kč
    • •
  • MŠMT
Project

Role of mitochondria in yeast colony differentiation and cell viability (GA19-09381S)

discovery of specific colony cell subpopulations and three distinct mitochondrial or determine target gene specificity in cell subpopulations. As mammalian mitochondrial in yeast and humans. Changes in mi...

Microbiology

  • 2019 - 2022
    • •
  • 9 879 tis. Kč
    • •
  • 9 624 tis. Kč
    • •
  • GA ČR
Project

Biofilm colonies of wild yeast Development, defense strategies and regulatory pathways (GA13-08605S)

cell subpopulations and function of protection mechanisms such as low-permeableDuring last years it has became evident that yeast (like other microorganisms) do not exist as individual cells in natural settings bu...

EB - Genetika a molekulární biologie

  • 2013 - 2017
    • •
  • 13 574 tis. Kč
    • •
  • 13 574 tis. Kč
    • •
  • GA ČR
Project

Metabolic pathways and regulatory mechanisms responsible for vitality and longevity of cells specifically localized within yeast colonies (GA15-08225S)

of the specific cell subpopulation localized at the particular position within ageing colonies. This subpopulation with metabolic features similar to mammalian tumor cells preserves vitalityDuring the past decade,...

EB - Genetika a molekulární biologie

  • 2015 - 2017
    • •
  • 10 430 tis. Kč
    • •
  • 10 430 tis. Kč
    • •
  • GA ČR
Project

Vital role of plasma membrane in cell interaction with exogenous proteins interaction of yeast plasma membrane with zymocines (GA204/00/0629)

Cell-to-cell communication is a crucial cell function. Some cells secrete hormones, mitogens, etc., that cause target cells to change their gene transcription. Among thereceptors that promote the entry of ...

EE - Mikrobiologie, virologie

  • 2000 - 2002
    • •
  • 3 101 tis. Kč
    • •
  • 1 996 tis. Kč
    • •
  • GA ČR
Project

Regulated cell death in multicellular spatially structured yeast populations Mechanisms and significance (LUAUS24055)

Programmed/regulated cell death (PCD/RCD) is integral to the development and aging of multicellular organisms, whether through the elimination of redundant cells during tissue differentiation, the elimination of damaged cells

Microbiology

  • 2024 - 2028
    • •
  • 9 882 tis. Kč
    • •
  • 9 882 tis. Kč
    • •
  • MŠMT
Project

The role of transposable elements in the dynamics of plant genomes (GA18-00258S)

whether retrotransposons can spread satellite DNA in the yeast genome. Our resultsTransposable elements (TEs) are a significant part of the plant genomes but their evolutionary dynamics and influence on cell funct...

Genetics and heredity (medical genetics to be 3)

  • 2018 - 2022
    • •
  • 8 731 tis. Kč
    • •
  • 7 844 tis. Kč
    • •
  • GA ČR
Project

The role of NK and NKT cells in the pathogenesis of primary idiopathic polymyositis and dermatomyositis (NR9106)

Characterization and differentiation of subpopulations of NK and NKT cells NK/NKT cell subpopulations in peripheral blood of PM/DM patients and healthy, effect of a therapy on distribution of NK and NKT cell

FP - Ostatní lékařské obory

  • 2006 - 2008
    • •
  • 4 797 tis. Kč
    • •
  • 4 539 tis. Kč
    • •
  • MZ
Project

Fission yeast CSL proteins in the maintenance of genome integrity (GPP305/12/P040)

in the maintenance of genome stability in fission yeast, a favourite model for DNA repairCells need to maintain the integrity of their DNA in order to transfer genetic interactions of CSL factors with DNA checkpoint/repair...

EB - Genetika a molekulární biologie

  • 2012 - 2014
    • •
  • 3 426 tis. Kč
    • •
  • 3 426 tis. Kč
    • •
  • GA ČR
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