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14 (0,142s) •

Project

Glycomic analysis of head and neck cancer - determination of prognostic relevance (NR9049)

beneficial glycobiologic prognostic factors will be determined. They will be finally...

FD - Onkologie a hematologie

  • 2006 - 2008
    • •
  • 2 657 tis. Kč
    • •
  • 2 657 tis. Kč
    • •
  • MZ
Project

Glycobiological characterization of head and neck tumors (GP304/03/P027)

will be investigated in this project. The assessment of glycobiological characterization...

EA - Morfologické obory a cytologie

  • 2003 - 2005
    • •
  • 738 tis. Kč
    • •
  • 738 tis. Kč
    • •
  • GA ČR
Project

Glycobiology of human epidermis in normal and pathologic conditions (GA304/04/0171)

The project is focussed on the glycobiological analysis of the epidermis in the selected skin diseases with defects in karatinocyte proliferation or differentiation. The aim is to characterize presence of selected lectins, their binding site...

EA - Morfologické obory a cytologie

  • 2004 - 2006
    • •
  • 1 692 tis. Kč
    • •
  • 1 692 tis. Kč
    • •
  • GA ČR
Project

Glycobiological investigations pertaining to biomolecular differentiation of mammary carcinomas (GA16-04496S)

Breast cancer is the most common cancer in women worldwide, with the incidence of mortality being particularly high in the Czech Republic. Progress in cancer biomarker discovery could have a substantial benefit to our society. New connections between...

FD - Onkologie a hematologie

  • 2016 - 2020
    • •
  • 3 512 tis. Kč
    • •
  • 3 005 tis. Kč
    • •
  • GA ČR
Project

Multifenotype profiling of head and neck squamous cell carcinomas - study of stem cell properties (GP304/08/P175)

glycobiological parameters (expression of endogenous lectins, e.g. galectins; lectin reactive...

EA - Morfologické obory a cytologie

  • 2008 - 2010
    • •
  • 1 842 tis. Kč
    • •
  • 1 842 tis. Kč
    • •
  • GA ČR
Project

Interdisciplinary approach to study biological systems at the molecular level (LTC17076)

Project is focused on innovative integrative biophysical approaches to study proteins involved in host-pathogen interaction. The topics is in line of the COST Action CA15126 focusing on the development of novel methodologies and technologies and help...

CE - Biochemie

  • 2017 - 2020
    • •
  • 1 827 tis. Kč
    • •
  • 1 827 tis. Kč
    • •
  • MŠMT
Project

Advanced glycomimetics in neurodegeneration research (GlycoDrug) (8X25048)

GlycoDrug project aims to develop new compound(s), which could bring a breakthrough in the treatment of Alzheimer's disease. The overall goal of the Croatian-Czech-Austrian GlycoDrug project is to conduct complex biological testing of the experimenta...

Pharmacology and pharmacy

  • 2025 - 2027
    • •
  • 247 tis. Kč
    • •
  • 247 tis. Kč
    • •
  • MŠMT
Project

Chemoinformatics for glycosynthesis (LD13024)

The major drawback of enzymatic synthesis of oligosaccharides and glycoconjugates is a lack of understanding of factors determining which substrate is suitable for given enzyme and which products are preferred in a reaction with multiple products. Th...

CE - Biochemie

  • 2013 - 2015
    • •
  • 1 305 tis. Kč
    • •
  • 1 305 tis. Kč
    • •
  • MŠMT
Project

Lyme borreliosis spirochetes molecular factors of protein-carbohydrate interactions (GA206/03/1323)

Selected glycobiological aspects of the Lyme borreliosis (LB) spirochetes are in a focus of the project with the emphasis on borrelia lectin (LEC), glycosylated stuctural components/antigens of the LB spirochtes, polysialic acid as a potenti...

EE - Mikrobiologie, virologie

  • 2003 - 2005
    • •
  • 1 560 tis. Kč
    • •
  • 1 560 tis. Kč
    • •
  • GA ČR
Project

a-N-Acetylgalactosaminidase and a-galactosidase-structural and functional characterisation, use in synthesis of biologically important glycoconjugates (GA203/05/0172)

The screening in fungal strains originating from public collections will create an enzyme library of a-N-acetylgalactosaminidases and a-galactosidases. a-Galactosidase from Talaromyces flavus identified as to be suitable for synthesis of glycosides o...

CE - Biochemie

  • 2005 - 2007
    • •
  • 3 586 tis. Kč
    • •
  • 3 586 tis. Kč
    • •
  • GA ČR
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