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7 877 (0,104s)

Project

Capillary electrophoresis based high-throughput system for beta-secretase inhibitor screening as a therapeutic target of Alzheimer's disease (GA16-06106S)

Reactor. They are probably the best candidates for high throughput screening of newThe aim of the project is the development of the high-throughput system based on capillary electrophoresis for the purpos...

CB - Analytická chemie, separace

  • 2016 - 2018
  • 6 006 tis. Kč
  • 5 613 tis. Kč
  • GA ČR
Project

System for searching for new biologically active compounds. Foccused combinatorial libraries. (FT-TA5/136)

IMG AS CR owns a unique technology for high-throughput screening for biological activity. RE&D VUFB company is experienced in medicinal chemistry and builds reach a new chemical entities and RE&D VUFB ability for screen...

CC - Organická chemie

  • 2008 - 2010
  • 11 224 tis. Kč
  • 7 127 tis. Kč
  • MPO
Project

Coupling of microchip with mass spectrometry for high throughput population and selective screening of inborn metabolic disorders (IBS4031209)

A large number of biochemical and clinical applications requires analytical procedures with positive identification of the analyzed substances by mass spectrometry. Such applications include analyses of protein digests, high throughput

CB - Analytická chemie, separace

  • 2002 - 2005
  • 4 263 tis. Kč
  • 4 133 tis. Kč
  • AV ČR
Project

ReceptorX Integrated platform for drug discovery and development (TA02010212)

Within the ReceptorX project the technological and informatics platform for nuclear receptor profiling will be established. The project is based on the collaboration of experts in research areas of nuclear receptors and high-throughput

EB - Genetika a molekulární biologie

  • 2012 - 2015
  • 26 037 tis. Kč
  • 15 373 tis. Kč
  • TA ČR
Project

Generation of high throughput in vitro models based on reporter gene assays for toxicological and environmental application (GA16-07544S)

to have sensitive, high throughput tool allowing screening and assessment of compounds endogenous receptor with reporter plasmid that will allow high throughput screening......

DN - Vliv životního prostředí na zdraví

  • 2016 - 2018
  • 4 691 tis. Kč
  • 4 691 tis. Kč
  • GA ČR
Project

High-throughput screening for new anthelmintics (LTC19030)

is the identification of novel structural classes of anthelmintics by the means of high-throughput screening on model nematode C. elegans . C. elegans is sensitive to most......

Microbiology

  • 2019 - 2021
  • 2 543 tis. Kč
  • 2 543 tis. Kč
  • MŠMT
Project

In vitro toxicological comparison of extracts of stressed transgenic and non-transgenic crops (LTC20015)

The aims of this project are: i) High-throughput screening of plant extracts comparing transgenic plant and its counterpart in order to a) evaluate the approaches which were used for genetic manipulation/edition from the t...

Food and beverages

  • 2020 - 2023
  • 4 117 tis. Kč
  • 4 117 tis. Kč
  • MŠMT
Project

High entropy disulfides simulation-driven fabrication of a new class of 2D materials (GA25-17542S)

Two-dimensional high entropy disulfides represent a new class of materials with unique properties. We will employ high-throughput atomistic simulations supported by machine learning to identify thermally stable materials by...

Materials engineering

  • 2025 - 2027
  • 10 941 tis. Kč
  • 9 791 tis. Kč
  • GA ČR
Project

DIANA - the analytical method for the determination of enzyme inhibition (GA19-10280S)

We propose to develop an advanced high-throughput screening (HTS) pipeline for identification of potent inhibitors of medicinally relevant enzymes, such as carbonic anhydrase IX (CAIX), glutamate carboxypeptidase II (GCPII)...

Biochemical research methods

  • 2019 - 2021
  • 5 295 tis. Kč
  • 4 944 tis. Kč
  • GA ČR
Project

Compound Stability in the Pharmaceutical and Agrochemical Industries (OE101)

Pharmaceutical and agrochemical companies store thousands of compounds for high throughput screening. Some of these are unstable and decompose. The project examines the causes of instability and develops predictive software...

CC - Organická chemie

  • 2002 - 2004
  • 9 220 tis. Kč
  • 2 784 tis. Kč
  • MŠMT
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