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Projects

64 projects (0,139s) •

Project

The hippocampus size in first-episode schizophrenia. (NF7028)

We are going to study relationship between hippocampus size and clinical. biochemical and cognitive parameters focused on frontal lobe function. These relations will be followed up longitudinaly.Their importance for the illness ourcome will ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2002 - 2004
    • •
  • 1 910 tis. Kč
    • •
  • 1 766 tis. Kč
    • •
  • MZ
Project

Correlation of MR spectroscopy image of hippocampus region and impairment of cognitive functions in patients after brain irradiation (NT14600)

to protect the hippocampus region during palliative radiation. Especially radiation with negative impact on their quality of life. In order to put the hippocampus-protecting in hippocampus (on metabolic level using spectro...

FD - Onkologie a hematologie

  • 2013 - 2015
    • •
  • 3 685 tis. Kč
    • •
  • 3 685 tis. Kč
    • •
  • MZ
Project

Can administration of corticosteroids lead to structural changes in hippocampus? Prospective MRI study in human patients treated with high doses of corticosteroids. (NF6489)

Using the MRI volumetry, neuropsychological assessment and endocrinological screening, we will elucidate the relationship between long term treatment with corticosteroids and structural and functional changes of hippocampus. 20 subjects (pow...

FH - Neurologie, neurochirurgie, neurovědy

  • 2001 - 2003
    • •
  • 2 185 tis. Kč
    • •
  • 2 172 tis. Kč
    • •
  • MZ
Project

Role of sleep in consolidation of associations between objects, positions and a time sequence – single unit activity in the hippocampus and neocortex (GJ17-26002Y)

A defining aspect of hippocampus-dependent episodic memory is remembering events within their spatial and temporal context. The overall goal of the proposed and neuronal ensembles of the hippocampus and neocortex. We designed a task...

FH - Neurologie, neurochirurgie, neurovědy

  • 2017 - 2021
    • •
  • 4 185 tis. Kč
    • •
  • 4 185 tis. Kč
    • •
  • GA ČR
Project

Role of glutamate in neurodegenerative changes induce by stress (NR9180)

Animals models show that exposure to high and/or long-term elevated levels of corticoids leads to structural changes in hippocampu. Similarly, humans afflicted and neurodegenerative changes in the hippocampus, the critical responsib...

FH - Neurologie, neurochirurgie, neurovědy

  • 2007 - 2009
    • •
  • 8 978 tis. Kč
    • •
  • 8 814 tis. Kč
    • •
  • MZ
Project

What is the unique contribution of the hippocampus in humans? (GA309/95/0730)

ED - Fyziologie

  • 1995 - 1995
    • •
  • 0 tis. Kč
    • •
  • 0 tis. Kč
    • •
  • GA ČR
Project

The role and the mechanism of segregation of information in the rat hippocampus in behavioural discrimination and in animal model of schizophrenia. (GPP303/10/P191)

The hippocampus is critical for memory of own experience. For this memory to be adaptive, its components need to be segregated into coherent representations so that they can be used in changed conditions. Infusion of tetrodotoxin (TTX) into ...

FH - Neurologie, neurochirurgie, neurovědy

  • 2010 - 2014
    • •
  • 1 587 tis. Kč
    • •
  • 1 587 tis. Kč
    • •
  • GA ČR
Project

In vitro effect of Ginkgo biloba extract on the activity of presynaptic cholinergic nerve terminals in rat hippocampus (GA307/95/1082)

FR - Farmakologie a lékárnická chemie

  • 1995 - 1996
    • •
  • 65 tis. Kč
    • •
  • 65 tis. Kč
    • •
  • GA ČR
Project

Role of astrocyte gap junctions in neurotransmission. (MEB021140)

The goal of this proposal is to identify novel mechanisms of interactions between neuroglial networks in the hippocampus. To test the hypothesis that the connectivity and Ca2+ signaling of astrocytic networks contribute to neuronal transmiss...

FH - Neurologie, neurochirurgie, neurovědy

  • 2011 - 2012
    • •
  • 128 tis. Kč
    • •
  • 128 tis. Kč
    • •
  • MŠMT
Project

Evaluation of lateralisation of nitric oxide mediator system in the hippocampus of people with schizophrenia and Alzheimer disease (NF7576)

Expression and activity of nitric oxide synthases and concentrations of L-glutamate, L-arginine, L-citrulline, nitrites/nitrates will be determined in both hippocampi of people with schizophrenia, Alzheimer disease amd multi-infarct dementia Laterali...

ED - Fyziologie

  • 2003 - 2005
    • •
  • 5 364 tis. Kč
    • •
  • 5 257 tis. Kč
    • •
  • MZ
  • 1 - 10 out of 64