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3 442 (0,119s) •

Project

Genetic consequences of population decline in Eurasian otter (Lutra lutra) populations in the Czech and Slovak Republics (KJB600930804)

and past microsatellite DNA variability in Czech and Slovak otter populations will be based on analysis of DNA extracted from tissue samples from otter carcasses (contemporarypopulation) and DNA extracted from teeth from s...

EG - Zoologie

  • 2008 - 2011
    • •
  • 1 993 tis. Kč
    • •
  • 1 993 tis. Kč
    • •
  • AV ČR
Project

Nucleotide polymorphism of mitochondrial genes of common carp Implication for phylogeography, evolutionary and colonization history (KJB608030901)

variation across contemporary and historical time scales. Using the phylogeographic framework, we shall assessed the DNA sequence variation at the mitochondrial and nuclear......

GL - Rybářství

  • 2009 - 2011
    • •
  • 1 317 tis. Kč
    • •
  • 1 317 tis. Kč
    • •
  • AV ČR
Project

Genetic diversity and structure of populations of the hermit (Chazara briseis) implications for its conservation and repatriation (SS07010270)

The main objective is to develop a methodological guideline for the preparation and implementation of a rescue program for the hermit (Chazara briseis) based on 1) a comparison of the genetic diversity and structure of its source, reintroduced, and <...

Biodiversity conservation

  • 2024 - 2026
    • •
  • 8 761 tis. Kč
    • •
  • 7 323 tis. Kč
    • •
  • TA ČR
Project

Genetic diversity of the critically endangered steppe polecat in the Czech Republic (SS07010351)

and nuclear DNA, 2) validation of recent and historical records of the steppe polecat...

Zoology

  • 2024 - 2026
    • •
  • 4 109 tis. Kč
    • •
  • 3 493 tis. Kč
    • •
  • TA ČR
Project

Applications of chemical structural probes and electroanalytical methods in DNA damage detection. Development of DNA sensors. (KJB4004302)

In this project we propose to employ chemical probing of DNA structure, in connection with biochemical methods and electrochemical detection, in analysis of DNA damage. Monitoring of DNA-damaging pollutants in the environme...

CG - Elektrochemie

  • 2003 - 2005
    • •
  • 2 052 tis. Kč
    • •
  • 1 212 tis. Kč
    • •
  • AV ČR
Project

Translesion DNA synthesis across lesions induced by agents of biological significance. An insight into energetics, kinetics and mechanism (GA17-09436S)

The biological effects of DNA-damaging physical and chemical agents are associated with their ability to affect DNA replication. The main objective of DNA due to its damage by DNA-damaging agents is an important fa...

BO - Biofyzika

  • 2017 - 2019
    • •
  • 5 627 tis. Kč
    • •
  • 5 006 tis. Kč
    • •
  • GA ČR
Project

Interactions of wild type and mutant p53 proteins with damaged DNA and their roles in cellular response to anticancer chemotherapy (IAA500040701)

Interactions of tumor suppressor protein p53 with DNA are crucial for its-specific DNA binding, but also ability of both wt and mutant (mut) p53 to recognize DNA and mut p53 interactions with damaged DNA, particula...

EB - Genetika a molekulární biologie

  • 2007 - 2010
    • •
  • 4 824 tis. Kč
    • •
  • 4 824 tis. Kč
    • •
  • AV ČR
Project

Development of electrochemical biodetectors for DNA damage (IAA4004108)

electrochemical biodetector (biosensor) for DNA damage (both in vitro and in cells) and DNA damaging agents. A procedure developed in our laboratory which allows to detect DNA strand breaks using mercury electrodes modifie...

CG - Elektrochemie

  • 2001 - 2003
    • •
  • 1 758 tis. Kč
    • •
  • 804 tis. Kč
    • •
  • AV ČR
Project

Extrachromosomal circular DNA and its impact on the evolution of plant satellite DNA (GP204/06/P360)

Satellite DNA formed by long arrays of repetitive tandemly arranged nucleotide recombination between repetitive units leading to formation of circular satellite DNA could extrachromosomal circular DNA with special impact on...

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 947 tis. Kč
    • •
  • 947 tis. Kč
    • •
  • GA ČR
Project

Triplex-forming DNA and its interactions with p53 proteins (GP204/06/P369)

Structure-selective DNA recognition is an important characteristic of not only). It is supposed that, besides its sequence, DNA conformation is crucial for p53-DNA and mutp53 with DNA containing sequences that adop...

EB - Genetika a molekulární biologie

  • 2006 - 2008
    • •
  • 1 197 tis. Kč
    • •
  • 1 197 tis. Kč
    • •
  • GA ČR
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